4 research outputs found
3D MHD Flux Emergence Experiments: Idealized models and coronal interactions
This paper reviews some of the many 3D numerical experiments of the emergence
of magnetic fields from the solar interior and the subsequent interaction with
the pre-existing coronal magnetic field. The models described here are
idealized, in the sense that the internal energy equation only involves the
adiabatic, Ohmic and viscous shock heating terms. However, provided the main
aim is to investigate the dynamical evolution, this is adequate. Many
interesting observational phenomena are explained by these models in a
self-consistent manner.Comment: Review article, accepted for publication in Solar Physic
Altered Cognitive Function in Men Treated for Prostate Cancer with LHRH Analogues and Cyproterone Acetate: A Randomised Controlled Trial
Objective. Luteinising hormone releasing hormone (LHRH) analogues have been associated with memory impairments in women using these drugs for gynaecological conditions. This is the first systematic investigation of the cognitive effects of LHRH analogues in male patients. Methods. 82 men with non-localised prostate cancer were randomly assigned to receive continuous leuprorelin (LHRH analogue), goserelin (LHRH analogue), cyproterone acetate (steroidal antiandrogen) or close clinical monitoring. These patients underwent cognitive assessments at baseline and before commencement of treatment (77) then 6 months later (65). Results. Compared with baseline assessments, men administered androgen suppression monotherapy performed worse in 2/12 tests of attention and memory. 24/50 men randomised to active treatment and assessed 6 months later demonstrated clinically significant decline in one or more cognitive tests but not one patient randomised to close monitoring showed a decline in any test performance. Conclusion. Pharmacological androgen suppression monotherapy for prostate cancer may be associated with impaired memory, attention and executive functions