Lamotrigine treatment of aggression in female borderline patients, Part II: an 18-month follow-up

Borderline patients often display pathological aggression. We previously tested lamotrigine, an anti-convulsant, in therapy for aggression in women with borderline personality disorder (BPD) (J Psychopharmacol 2005; 19: 287–291), and found significant changes on most scales of the State-Trait Anger Expression Inventory (STAXI) after eight weeks. To assess the longerterm efficacy of lamotrigine in therapy for aggression in women with BPD, this 18-month follow-up observation was carried out, in which patients (treated with lamotrigine: n = 18; former placebo group: n = 9) were tested every six months. According to the intent-to-treat principle, significant changes on all scales of the STAXI were observed in the lamotrigine-treated subjects. All subjects tolerated lamotrigine relatively well. Lamotrigine appears to be an effective and relatively safe agent in the longer-term treatment of aggression in women with BPD

Confirmatory factor analysis of the thought occurrence questionnaire for sport (TOQS) among adolescent athletes

There is an inherent link between theory and measurement suggesting that validation of measures should be the first stage of theory testing. The aim of the present study was to cross-validate the factorial validity of the Thought Occurrence Questionnaire for Sport for use among adolescent athletes. National standard young athletes (Individual N_/204; Team N_/360) completed the TOQS questionnaire. Single-sample and multisample confirmatory factor analysis provided support for the psychometric integrity of the hypothesized three-factor correlated model. Multisample results demonstrated invariance for factor loadings and correlations between individual and team athletes. Internal consistency coefficients were over the .70 criterion for acceptability. Findings lend support to previous validation studies conducted on samples of adult athletes and suggest that the TOQS provides an equally valid measure for use among adolescent athletes. It is suggested that the TOQS can be used to investigate theoretical issues related to cognitive interference during competition