Sagliker syndrome: Uglifying human face appearance in late and severe secondary hyperparathyroidism in chronic renal failure

PubMedID: 15490409Almost every patient with chronic renal failure (CRF) eventually develops secondary hyperparathyroidism (SH) unless they are treated with proper and novel medications in advanced medical centers by skilled medical personnel. Every kind of bone abnormality including skull deformities has been described in detail by almost every concerned researcher and textbook, but descriptions of this phenomenon are limited in the medical literature to the years from 1973 to 1977. To our knowledge, extensive data regarding uglifying human face appearances have not been defined so far in the literature. We are therefore making this addition to the clinical nephrology field by accumulating such data. After we found 2 consecutive peculiar and unique patients with uglifying human face appearances in 2000, we attempted to inform and draw attention to this new entity to all hemodialysis (HD) centers in Turkey, as well as in other developing countries around the world to collect data on this phenomenon. Accordingly, we visited dialysis centers and patients' houses to collect detailed information, including medical clinical histories, physical examinations, laboratory data, biographies, current medications, and so forth. We found 25 patients who had CRF, SH, short stature, extremely severe skull changes, maxillary and mandibular bone changes, teeth/dental abnormalities, and soft and innocuous tumoral tissues in the mouth (hence, uglifying the appearance of the face), fingertip changes, severe psychologic problems, and depression. It appears that patients with CRF may have a new syndrome of bone deformities that have long been neglected, ignored, and forgotten since the mid-1970s when they were first described. This is vital and critical information for the clinical status of patients who suffered from the syndrome that we have named Sagliker syndrome (SS), and we believe there are many more patients in the world who are suffering from it. © 2004 Elsevier Inc. All rights reserved

Hypertensionologist' hypertension. Multiple-salvo manual BP recordings-medical harakiri procedures must be banned by legistlations via ESH, ISH and WHO. This phenomenon may be named Sagliker Effect (SE)

18th Scientific Meeting of the European-Society-of-Hypertension/22nd Scientific Meeting of the International-Society-of-Hypertension -- JUN 14-19, 2008 -- Berlin, GERMANYWOS: 000257197003419…Euorpean Soc Hyperten, Deutsch Hochdrucklig

TRANSCUTANEOUS ELECTRICAL NERVE STIMULATION (TENS) IN PERIPHERAL POLYNEUROPATHY IN DIABETES MELLITUS, CHRONIC KIDNEY DISEASE AND PRIMARY HYPERTENSION

WOS: 000456877501043

FIRST MEDICAL WARNING. A REAL HARAKIRI. HYPERTENSIONOLOGIST'S HYPERTENSION. SAGLIKER EFFECT. CLASSICAL MANUAL BP MEASUREMENTS MUST BE BANNED BY LEGISLATIONS AND ESH AND WHO

WOS: 000440355102109

PRIMAR HYPERTENSION. EARLY NEPHROSCLEROSIS BEGINS FIRST WITHIN THE LEFT KIDNEY. ERGUN'S SIGN

WOS: 000456877501148

STRIKING EFFICACY OF TRANSCUTANEOUS ELECTRICAL NERVE STIMULATIONS IN PERIPHERAL POLYNEUROPATHIES IN DIABETES MELLITUS II-I, CKD IV-V AND PRIMARY HYPERTENSION

WOS: 000440355102045

Sagliker effect (SE) and hypertensionologist hypertension in medical doctors and nurses. Multiple-salvo manual BP recordings which are medical harakiri procedures must be banned

16th European Meeting on Hypertension -- JUN 12-15, 2006 -- Madrid, SPAINWOS: 000240281002466…European Soc Hyperten

IS IT A PROMISING MIRACLEOUS THERAPY ?HIGH-TONE EXTERNAL MUSCLE STIMULATION ELECTROTHERAPHY IN THE TREATMENTS OF RESISTANT AND IRREVERSIBLE SYMPTOMATIC PERIPHERIC POLYNEUROPATHY WITH DIABETES MELLITUS, CHRONIC KIDNEY DISEASE AND PRIMARY HYPERTENSIVES

49th Congress of the European-Renal-Association/European-Dialysis-and-Transplant-Association (ERA-EDTA) -- MAY 24-27, 2012 -- Paris, FRANCEWOS: 000311494700216…European Renal Assoc (ERA), European Dialysis & Transplant Assoc (EDTA