22,489 research outputs found
High voltage characteristics of the electrodynamic tether and the generation of power and propulsion
The Tethered Satellite System (TSS) will deploy and retrieve a satellite from the Space Shuttle orbiter with a tether of up to 100 km in length attached between the satellite and the orbiter. The characteristics of the TSS which are related to high voltages, electrical currents, energy storage, power, and the generation of plasma waves are described. A number of specific features of the tether system of importance in assessing the operational characteristics of the electrodynamic TSS are identified
Radio-wave propagation in the non-Gaussian interstellar medium
Radio waves propagating from distant pulsars in the interstellar medium
(ISM), are refracted by electron density inhomogeneities, so that the intensity
of observed pulses fluctuates with time. The theory relating the observed pulse
time-shapes to the electron-density correlation function has developed for 30
years, however, two puzzles have remained. First, observational scaling of
pulse broadening with the pulsar distance is anomalously strong; it is
consistent with the standard model only when non-uniform statistics of electron
fluctuations along the line of sight are assumed. Second, the observed pulse
shapes are consistent with the standard model only when the scattering material
is concentrated in a narrow slab between the pulsar and the Earth.
We propose that both paradoxes are resolved at once if one assumes stationary
and uniform, but non-Gaussian statistics of the electron-density distribution.
Such statistics must be of Levy type, and the propagating ray should exhibit a
Levy flight. We propose that a natural realization of such statistics may be
provided by the interstellar medium with random electron-density
discontinuities. We develop a theory of wave propagation in such a non-Gaussian
random medium, and demonstrate its good agreement with observations. The
qualitative introduction of the approach and the resolution of the
anomalous-scaling paradox was presented earlier in [PRL 91, 131101 (2003); ApJ
584, 791 (2003)].Comment: 27 pages, changes to match published versio
The motion of ascending and descending spheres
Measurements of self-induced motions of spheres ascending and descending in deep water tan
Anomalous Radio-Wave Scattering from Interstellar Plasma Structures
This paper considers scattering screens that have arbitrary spatial
variations of scattering strength transverse to the line of sight, including
screens that are spatially well confined, such as disks and filaments. We
calculate the scattered image of a point source and the observed pulse shape of
a scattered impulse. The consequences of screen confinement include: (1) Source
image shapes that are determined by the physical extent of the screen rather
than by the shapes of much-smaller diffracting microirregularities. These
include image elongations and orientations that are frequency dependent. (2)
Variation with frequency of angular broadening that is much weaker than the
trademark \nu^{-2} scaling law (for a cold, unmagnetized plasma), including
frequency-independent cases; and (3) Similar departure of the pulse broadening
time from the usually expected \nu^{-4} scaling law. We briefly discuss
applications that include scattering of pulses from the Crab pulsar by
filaments in the Crab Nebula; image asymmetries from Galactic scattering of the
sources Cyg X-3, Sgr A*, and NGC 6334B; and scattering of background active
galactic nuclei by intervening galaxies. We also address the consequences for
inferences about the shape of the wavenumber spectrum of electron density
irregularities, which depend on scaling laws for the image size and the pulse
broadening. Future low-frequency (< 100 MHz) array observations will also be
strongly affected by the Galactic structure of scattering material. Our
formalism is derived in the context of radio scattering by plasma density
fluctuations. It is also applicable to optical, UV and X-ray scattering by
grains in the interstellar medium.Comment: 21 pages, LaTeX2e with AASTeX-4.0, 6 PostScript figures, accepted by
ApJ, revised version has minor changes to respond to referee comments and
suggestion
What can GLAST say about the origin of cosmic rays in other galaxies ?
Gamma rays in the band from 20 MeV to 300 GeV, used in combination with data
from radio and X-ray bands, provide a powerful tool for studying the origin of
cosmic rays in our sister galaxies Andromeda and the Magellanic Clouds.
Gamma-ray Large Area Space Telescope (GLAST) will spatially resolve these
galaxies and measure the spectrum and intensity of diffuse gamma radiation from
the collisions of cosmic rays with gas and dust in them. Observations of
Andromeda will give an external perspective on a spiral galaxy like the Milky
Way. Observations of the Magellanic Clouds will permit a study of cosmic rays
in dwarf irregular galaxies, where the confinement is certainly different and
the massive star formation rate is much greater.Comment: 4 pages including 6 figures; to appear in Proc. ACE-2000 Symp. "The
Acceleration and Transport of Energetic Particles Observed in the
Heliosphere" (Jan. 5-8, 2000, Indian Wells, CA), AIP Conf. Proc. More details
can be found at the LHEA GLAST page at
http://lhea-glast.gsfc.nasa.gov/pub/science/index.htm
A CLEAN-based Method for Deconvolving Interstellar Pulse Broadening from Radio Pulses
Multipath propagation in the interstellar medium distorts radio pulses, an
effect predominant for distant pulsars observed at low frequencies. Typically,
broadened pulses are analyzed to determine the amount of propagation-induced
pulse broadening, but with little interest in determining the undistorted pulse
shapes. In this paper we develop and apply a method that recovers both the
intrinsic pulse shape and the pulse broadening function that describes the
scattering of an impulse. The method resembles the CLEAN algorithm used in
synthesis imaging applications, although we search for the best pulse
broadening function, and perform a true deconvolution to recover intrinsic
pulse structre. As figures of merit to optimize the deconvolution, we use the
positivity and symmetry of the deconvolved result along with the mean square
residual and the number of points below a given threshold. Our method makes no
prior assumptions about the intrinsic pulse shape and can be used for a range
of scattering functions for the interstellar medium. It can therefore be
applied to a wider variety of measured pulse shapes and degrees of scattering
than the previous approaches. We apply the technique to both simulated data and
data from Arecibo observations.Comment: 9 pages, 6 figures, Accepted for publication in the Astrophysical
Journa
Estimating Small Area Income Deprivation: An Iterative Proportional Fitting Approach
Small area estimation and in particular the estimation of small area income deprivation has
potential value in the development of new or alternative components of multiple deprivation
indices. These new approaches enable the development of income distribution threshold based
as opposed to benefit count based measures of income deprivation and so enable the
alignment of regional and national measures such as the Households Below Average Income
with small area measures. This paper briefly reviews a number of approaches to small area
estimation before describing in some detail an iterative proportional fitting based spatial
microsimulation approach. This approach is then applied to the estimation of small area HBAI
rates at the small area level in Wales in 2003-5. The paper discusses the results of this
approach, contrasts them with contemporary ‘official’ income deprivation measures for the
same areas and describes a range of ways to assess the robustness of the results
Equatorial X-rays and their effect on the lower mesosphere
On the night of May 23/24, 1975, a sequence of rocket and balloon experiments was launched from Chilca Base, Peru (12.5 deg S, 76.8 deg W, magnetic dip = - 0.7 deg). Detailed analysis and comparisons of the data yielded the first direct measurement of lower mesospheric response to a galactic X-ray source. This result could only have been determined at the equator, where cosmic ray background effects are minimal. The objective of the experiments was to seek out the equatorial energetic electron belt, sporadically reported to contain fluxes near auroral levels, measure the bremsstrahlung radiation produced by this particle belt, and determine the influence of this radiation on the middle atmosphere. High altitude rocket payloads (Nike Tomahawk 18.170 and 18.171) were launched to probe the thermosphere during and following the anticipated downward drift period. Each carried an on-axis X-ray scintillation detector and Geiger Mueller energetic electron detectors. Magnetometers and lunar sensors were used to determine payload aspect
Towards a killer app for the Semantic Web
Killer apps are highly transformative technologies that create new markets and widespread patterns of behaviour. IT generally, and the Web in particular, has benefited from killer apps to create new networks of users and increase its value. The Semantic Web community on the other hand is still awaiting a killer app that proves the superiority of its technologies. There are certain features that distinguish killer apps from other ordinary applications. This paper examines those features in the context of the Semantic Web, in the hope that a better understanding of the characteristics of killer apps might encourage their consideration when developing Semantic Web applications
Bleomycin increases neutrophil adhesion to human vascular endothelial cells independently of upregulation of ICAM-1 and E-selectin
© 2016 Taylor & Francis. Aim of the Study: Bleomycin-induced lung disease is a serious complication of therapy characterized by alveolar injury, cytokine release, inflammatory cell recruitment, and eventually pulmonary fibrosis. The mechanisms underlying bleomycin-induced pulmonary fibrosis may be relevant to other progressive scarring diseases of the lungs. Pulmonary vascular endothelial cells are critically involved in immune cell extravasation at sites of injury through adhesion molecule expression and cytokine release. We sought to determine the effects of bleomycin on adhesion molecule expression and cytokine release by pulmonary vascular endothelial cells, and their functional relevance to inflammatory cell recruitment. Materials and Methods: The effects of pharmacologically relevant concentrations of bleomycin on adhesion molecule expression and cytokine release by human vascular endothelial cells in vitro were studied by flow cytometry, quantitative polymerase chain reaction, and enzyme-linked immunosorbent assay. A flow chamber model was used to assess the functional consequences on adhesion of flowing human neutrophils to endothelial cell monolayers. Results: Bleomycin increased intercellular adhesion molecule 1 (ICAM-1; CD54), vascular cell adhesion molecule (VCAM-1; CD106), and E-selectin (CD62E) expression, and increased monocyte chemoattractant protein (MCP-1) and interleukin (IL-8) release by endothelial cells. Increases in protein expression were accompanied by increased mRNA transcription. In contrast, there was no direct effect of bleomycin on the profibrotic cytokines transforming growth factor-beta (TGF-β), platelet-derived growth factor-BB (PDGF-BB), or endothelin-1. Under flow conditions, endothelial cells exposed to bleomycin supported increased neutrophil adhesion which was independent of ICAM-1 or E-selectin. Conclusion: Our findings demonstrate that bleomycin promotes endothelial-mediated inflammation and neutrophil adhesion. These mechanisms may contribute to the development of pulmonary fibrosis by supporting immune cell recruitment in the lungs
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