19 research outputs found

    120 Π»Π΅Ρ‚ ΠΊΠ°Ρ„Π΅Π΄Ρ€Π΅ Π΄Π΅Ρ€ΠΌΠ°Ρ‚ΠΎΠ²Π΅Π½Π΅Ρ€ΠΎΠ»ΠΎΠ³ΠΈΠΈ Бибирского государствСнного мСдицинского унивСрситСта

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    A 120-years history of the Dermatovenerology Chair of SibirianStateMedicalUniversityis presented. The contribution of the scientists into the theory and practice in dermatovenerology and traning of specialists is described. The advances of the last 10 years are shown.ΠŸΡ€Π΅Π΄ΡΡ‚Π°Π²Π»Π΅Π½Π° история становлСния ΠΈ развития ΠΊΠ°Ρ„Π΅Π΄Ρ€Ρ‹ Π΄Π΅Ρ€ΠΌΠ°Ρ‚ΠΎΠ²Π΅Π½Π΅Ρ€ΠΎΠ»ΠΎΠ³ΠΈΠΈ Π»Π΅Ρ‡Π΅Π±Π½ΠΎΠ³ΠΎ Ρ„Π°ΠΊΡƒΠ»ΡŒΡ‚Π΅Ρ‚Π° Π‘ΠΈΠ±Π“ΠœΠ£ Π·Π° 120 Π»Π΅Ρ‚. Описан Π²ΠΊΠ»Π°Π΄ ΡƒΡ‡Π΅Π½Ρ‹Ρ… Π² Ρ‚Π΅ΠΎΡ€ΠΈΡŽ ΠΈ ΠΏΡ€Π°ΠΊΡ‚ΠΈΠΊΡƒ Π΄Π΅Ρ€ΠΌΠ°Ρ‚ΠΎΠ²Π΅Π½Π΅Ρ€ΠΎΠ»ΠΎΠ³ΠΈΠΈ, ΠΏΠΎΠ΄Π³ΠΎΡ‚ΠΎΠ²ΠΊΡƒ ΠΊΠ°Π΄Ρ€ΠΎΠ². ΠžΠ±ΠΎΠ·Π½Π°Ρ‡Π΅Π½Ρ‹ достиТСния послСднСго дСсятилСтия

    ΠžΠŸΠ’Π˜Π§Π•Π‘ΠšΠ˜Π™ Π‘ΠŸΠ•ΠšΠ’Π  ΠžΠ’Π ΠΠ–Π•ΠΠ˜Π― ΠšΠžΠ–Π˜ ПРИ Π’Π˜Π’Π˜Π›Π˜Π“Πž

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    Vitiligo is a disease with unknown etiology, which is characterized by skin depigmentation areas due to melanocyte death. Lack of clear understanding of pathogenic disease processes justifies the difficulty of choosing efficient treatment methods. Repigmentation is slow and not always complete. One of the key indicators in practical dermatology is objective assessment of skin cover condition for further diagnostics, definition of therapy and dynamics of the disease.The purpose of this study is to assess skin reflection spectrum in depigmentation areas, marginal layer and visible healthy skin before and after treatment of patients with vitiligo.21 patients having vitiligo were under observation; the patients were treated in the hospital of skin and venereal diseases of the Siberian State Medical University. The authors applied noninvasive method of spectrophotometry for the first time in order to study skin reflection spectrum of patients with vitiligo. Noninvasive medical spectrophotometry is based on dependence factor of integral optical properties of biological tissues and fluids in the conditions of homeostasis and in case of pathology. In order to assess the efficiency of skin disease treatment the patients were exposed to skin spectrophotometry before the beginning of the treatment and after the treatment itself with further measurements of the reflection spectrum integral criteria. The measurements were made in depigmentation area, on the boundary with healthy skin and in remote from depigmentation area of healthy skin.Obtained results indicate the difference of skin reflection spectra in the areas under investigation. Moreover, positive dynamics of the treatment associated with the decrease in the value of reflection spectrum integral criteria in the diseased area. There were no statistically important differences of the integral criteria, calculated based on measurement results of reflection spectra on the boundary of depigmentation area before and after treatment. Most likely this is related to active processes of repigmentation in the skin in the course of the treatment.For detailed study of identified phenomena there is a need for thorough study and expansion of the list of dermatologic diseases.Π’ΠΈΡ‚ΠΈΠ»ΠΈΠ³ΠΎ являСтся Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΠ΅ΠΌ с нСизвСстной этиологиСй, Ρ…Π°Ρ€Π°ΠΊΡ‚Π΅Ρ€ΠΈΠ·ΡƒΡŽΡ‰ΠΈΠΌΡΡ ΠΎΡ‡Π°Π³Π°ΠΌΠΈ Π΄Π΅ΠΏΠΈΠ³ΠΌΠ΅Π½Ρ‚Π°Ρ†ΠΈΠΈ ΠΊΠΎΠΆΠΈ Π² связи с гибСлью ΠΌΠ΅Π»Π°Π½ΠΎΡ†ΠΈΡ‚ΠΎΠ². ΠžΡ‚ΡΡƒΡ‚ΡΡ‚Π²ΠΈΠ΅ Ρ‡Π΅Ρ‚ΠΊΠΈΡ… прСдставлСний ΠΎ патогСнСтичСских ΠΌΠ΅Ρ…Π°Π½ΠΈΠ·ΠΌΠ°Ρ… заболСвания ΠΎΠ±ΡŠΡΡΠ½ΡΠ΅Ρ‚ затруднСния Π² ΠΏΠΎΠ΄Π±ΠΎΡ€Π΅ эффСктивных ΠΌΠ΅Ρ‚ΠΎΠ΄ΠΎΠ² лСчСния. РСпигмСнтация ΠΏΡ€ΠΎΡ‚Π΅ΠΊΠ°Π΅Ρ‚ ΠΌΠ΅Π΄Π»Π΅Π½Π½ΠΎ ΠΈ Π½Π΅ всСгда Π±Ρ‹Π²Π°Π΅Ρ‚ ΠΏΠΎΠ»Π½ΠΎΠΉ. Одним ΠΈΠ· Π²Π°ΠΆΠ½Ρ‹Ρ… ΠΏΠΎΠΊΠ°Π·Π°Ρ‚Π΅Π»Π΅ΠΉ Π² практичСской Π΄Π΅Ρ€ΠΌΠ°Ρ‚ΠΎΠ»ΠΎΠ³ΠΈΠΈ являСтся ΠΎΠ±ΡŠΠ΅ΠΊΡ‚ΠΈΠ²Π½Π°Ρ ΠΎΡ†Π΅Π½ΠΊΠ° состояния ΠΊΠΎΠΆΠ½Ρ‹Ρ… ΠΏΠΎΠΊΡ€ΠΎΠ²ΠΎΠ² для диагностики, ΠΎΠΏΡ€Π΅Π΄Π΅Π»Π΅Π½ΠΈΠ΅ эффСктивности ΠΏΡ€ΠΎΠ²ΠΎΠ΄ΠΈΠΌΠΎΠΉ Ρ‚Π΅Ρ€Π°ΠΏΠΈΠΈ ΠΈ Π΄ΠΈΠ½Π°ΠΌΠΈΠΊΠΈ заболСвания.ЦСлью настоящСго исслСдования Π±Ρ‹Π»Π° ΠΎΡ†Π΅Π½ΠΊΠ° спСктра отраТСния ΠΊΠΎΠΆΠΈ Π² ΠΎΡ‡Π°Π³Π°Ρ… Π΄Π΅ΠΏΠΈΠ³ΠΌΠ΅Π½Ρ‚Π°Ρ†ΠΈΠΈ, ΠΊΡ€Π°Π΅Π²ΠΎΠΉ Π·ΠΎΠ½Π΅ ΠΈ Π²ΠΈΠ΄ΠΈΠΌΠΎ Π·Π΄ΠΎΡ€ΠΎΠ²ΠΎΠΉ ΠΊΠΎΠΆΠΈ Π΄ΠΎ ΠΈ послС лСчСния Ρƒ ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ² с Π²ΠΈΡ‚ΠΈΠ»ΠΈΠ³ΠΎ.Под наблюдСниСм находился 21 ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ с Π²ΠΈΡ‚ΠΈΠ»ΠΈΠ³ΠΎ, ΠΏΠΎΠ»ΡƒΡ‡Π°Π²ΡˆΠΈΠΉ Π»Π΅Ρ‡Π΅Π½ΠΈΠ΅ ΠΏΠΎ Π΄Π°Π½Π½ΠΎΠΌΡƒ заболСванию Π² ΠΊΠ»ΠΈΠ½ΠΈΠΊΠ΅ ΠΊΠΎΠΆΠ½Ρ‹Ρ… ΠΈ вСнСричСских Π±ΠΎΠ»Π΅Π·Π½Π΅ΠΉ Бибирского государствСнного мСдицинского унивСрситСта (Π³. Вомск). Авторами Π²ΠΏΠ΅Ρ€Π²Ρ‹Π΅ Π±Ρ‹Π» ΠΏΡ€ΠΈΠΌΠ΅Π½Π΅Π½ Π½Π΅ΠΈΠ½Π²Π°Π·ΠΈΠ²Π½Ρ‹ΠΉ ΠΌΠ΅Ρ‚ΠΎΠ΄ спСктрофотомСтрии с Ρ†Π΅Π»ΡŒΡŽ изучСния спСктра отраТСния ΠΊΠΎΠΆΠΈ Ρƒ Π±ΠΎΠ»ΡŒΠ½Ρ‹Ρ… Π²ΠΈΡ‚ΠΈΠ»ΠΈΠ³ΠΎ. НСинвазивная мСдицинская спСктрофотомСтрия основываСтся Π½Π° Ρ„Π°ΠΊΡ‚Π΅ зависимости ΠΈΠ½Ρ‚Π΅Π³Ρ€Π°Π»ΡŒΠ½Ρ‹Ρ… оптичСских свойств биологичСских Ρ‚ΠΊΠ°Π½Π΅ΠΉ ΠΈ ТидкостСй Π² условиях гомСостаза ΠΈ ΠΏΡ€ΠΈ ΠΏΠ°Ρ‚ΠΎΠ»ΠΎΠ³ΠΈΠΈ. Для ΠΎΡ†Π΅Π½ΠΊΠΈ эффСктивности лСчСния ΠΊΠΎΠΆΠ½ΠΎΠ³ΠΎ процСсса ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚Π°ΠΌ ΠΏΠ΅Ρ€Π΅Π΄ Π½Π°Ρ‡Π°Π»ΠΎΠΌ курса Ρ‚Π΅Ρ€Π°ΠΏΠΈΠΈ ΠΈ послС окончания лСчСния ΠΏΡ€ΠΎΠ²ΠΎΠ΄ΠΈΠ»Π°ΡΡŒ спСктрофотомСрия ΠΊΠΎΠΆΠΈ с ΠΏΠΎΡΠ»Π΅Π΄ΡƒΡŽΡ‰ΠΈΠΌ вычислСниСм ΠΈΠ½Ρ‚Π΅Π³Ρ€Π°Π»ΡŒΠ½ΠΎΠ³ΠΎ критСрия спСктра отраТСния. Π˜Π·ΠΌΠ΅Ρ€Π΅Π½ΠΈΡ ΠΏΡ€ΠΎΠ²ΠΎΠ΄ΠΈΠ»ΠΈ Π² ΠΎΡ‡Π°Π³Π΅ Π΄Π΅ΠΏΠΈΠ³ΠΌΠ΅Π½Ρ‚Π°Ρ†ΠΈΠΈ, Π½Π° Π³Ρ€Π°Π½ΠΈΡ†Π΅ со Π·Π΄ΠΎΡ€ΠΎΠ²ΠΎΠΉ ΠΊΠΎΠΆΠ΅ΠΉ ΠΈ Π² ΠΎΡ‚Π΄Π°Π»Π΅Π½Π½ΠΎΠΌ ΠΎΡ‚ ΠΎΡ‡Π°Π³Π° Π΄Π΅ΠΏΠΈΠ³ΠΌΠ΅Π½Ρ‚Π°Ρ†ΠΈΠΈ Π·Π΄ΠΎΡ€ΠΎΠ²ΠΎΠΌ участкС ΠΊΠΎΠΆΠΈ.ΠŸΠΎΠ»ΡƒΡ‡Π΅Π½Π½Ρ‹Π΅ Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹ ΡΠ²ΠΈΠ΄Π΅Ρ‚Π΅Π»ΡŒΡΡ‚Π²ΡƒΡŽΡ‚ ΠΎ Ρ€Π°Π·Π»ΠΈΡ‡ΠΈΠΈ спСктров отраТСния ΠΊΠΎΠΆΠΈ Π² исслСдуСмых Π·ΠΎΠ½Π°Ρ…. ΠšΡ€ΠΎΠΌΠ΅ Ρ‚ΠΎΠ³ΠΎ, ΠΏΠΎΠ»ΠΎΠΆΠΈΡ‚Π΅Π»ΡŒΠ½Π°Ρ Π΄ΠΈΠ½Π°ΠΌΠΈΠΊΠ° лСчСния Π°ΡΡΠΎΡ†ΠΈΠΈΡ€ΠΎΠ²Π°Π»Π°ΡΡŒ с ΡƒΠΌΠ΅Π½ΡŒΡˆΠ΅Π½ΠΈΠ΅ΠΌ значСния ΠΈΠ½Ρ‚Π΅Π³Ρ€Π°Π»ΡŒΠ½ΠΎΠ³ΠΎ критСрия спСктра отраТСния Π² ΠΎΡ‡Π°Π³Π΅ пораТСния. БтатистичСски Π·Π½Π°Ρ‡ΠΈΠΌΡ‹Π΅ различия ΠΈΠ½Ρ‚Π΅Π³Ρ€Π°Π»ΡŒΠ½ΠΎΠ³ΠΎ критСрия, рассчитанного ΠΏΠΎ Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Π°ΠΌ измСрСния спСктров отраТСния Π½Π° Π³Ρ€Π°Π½ΠΈΡ†Π΅ ΠΎΡ‡Π°Π³Π° Π΄Π΅ΠΏΠΈΠ³ΠΌΠ΅Π½Ρ‚Π°Ρ†ΠΈΠΈ Π΄ΠΎ ΠΈ послС лСчСния, Π° Ρ‚Π°ΠΊΠΆΠ΅ Π½Π° Π³Ρ€Π°Π½ΠΈΡ†Π΅ Π²ΠΈΡ‚ΠΈΠ»ΠΈΠ³ΠΈΠ½ΠΎΠ·Π½ΠΎΠ³ΠΎ ΠΎΡ‡Π°Π³Π° ΠΈ Π·Π΄ΠΎΡ€ΠΎΠ²ΠΎΠΉ ΠΊΠΎΠΆΠΈ послС лСчСния отсутствовали. ВСроятно, это связано с Π°ΠΊΡ‚ΠΈΠ²Π½ΠΎ ΠΏΡ€ΠΎΡ‚Π΅ΠΊΠ°ΡŽΡ‰ΠΈΠΌΠΈ процСссами Ρ€Π΅ΠΏΠΈΠ³ΠΌΠ΅Π½Ρ‚Π°Ρ†ΠΈΠΈ Π² ΠΊΠΎΠΆΠ΅ Π½Π° Ρ„ΠΎΠ½Π΅ ΠΏΡ€ΠΎΠ²ΠΎΠ΄ΠΈΠΌΠΎΠ³ΠΎ лСчСния.Для Π΄Π΅Ρ‚Π°Π»ΡŒΠ½ΠΎΠ³ΠΎ изучСния ΠΎΠ±Π½Π°Ρ€ΡƒΠΆΠ΅Π½Π½Ρ‹Ρ… закономСрностСй Π½Π΅ΠΎΠ±Ρ…ΠΎΠ΄ΠΈΠΌΠΎ ΠΏΡ€ΠΎΠ²Π΅Π΄Π΅Π½ΠΈΠ΅ Ρ€Π°Π·Π²Π΅Ρ€Π½ΡƒΡ‚ΠΎΠ³ΠΎ исслСдования ΠΈ Ρ€Π°ΡΡˆΠΈΡ€Π΅Π½ΠΈΡ пСрСчня дСрматологичСских Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΠΉ

    ВозмоТности соврСмСнных ΠΌΠ΅Ρ‚ΠΎΠ΄ΠΎΠ² Π»ΡƒΡ‡Π΅Π²ΠΎΠΉ диагностики ΠΏΡ€ΠΈ псориатичСском Π°Ρ€Ρ‚Ρ€ΠΈΡ‚Π΅

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    The comparative evaluation of modern imaging methods gives evidence of great opportunities of both MRT and US in the detection of structural alterations of joints at psoriatic arthritis. The key role is assigned to ultrasonography which has proved to be highly sensitive in the disclosure of peripheral joint synovitis and allows the follow-up during the treatment course.Π‘Ρ€Π°Π²Π½ΠΈΡ‚Π΅Π»ΡŒΠ½Π°Ρ ΠΎΡ†Π΅Π½ΠΊΠ° соврСмСнных ΠΌΠ΅Ρ‚ΠΎΠ΄ΠΎΠ² Π²ΠΈΠ·ΡƒΠ°Π»ΠΈΠ·Π°Ρ†ΠΈΠΈ ΡΠ²ΠΈΠ΄Π΅Ρ‚Π΅Π»ΡŒΡΡ‚Π²ΡƒΠ΅Ρ‚ ΠΎ Π±ΠΎΠ»ΡŒΡˆΠΈΡ… возмоТностях ΠΊΠ°ΠΊ магнитнорСзонансной Ρ‚ΠΎΠΌΠΎΠ³Ρ€Π°Ρ„ΠΈΠΈ, Ρ‚Π°ΠΊ ΠΈ ΡƒΠ»ΡŒΡ‚Ρ€Π°Π·Π²ΡƒΠΊΠΎΠ²ΠΎΠ³ΠΎ исслСдования Π² ΠΎΠ±Π½Π°Ρ€ΡƒΠΆΠ΅Π½ΠΈΠΈ структурных ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΠΉ суставов ΠΏΡ€ΠΈ псориатичСском Π°Ρ€Ρ‚Ρ€ΠΈΡ‚Π΅. Особая Ρ€ΠΎΠ»ΡŒ отводится ΡƒΠ»ΡŒΡ‚Ρ€Π°Π·Π²ΡƒΠΊΠΎΠ²ΠΎΠΌΡƒ исслСдованию, ΠΊΠΎΡ‚ΠΎΡ€ΠΎΠ΅ ΠΎΠ±Π»Π°Π΄Π°Π΅Ρ‚ высокой Ρ‡ΡƒΠ²ΡΡ‚Π²ΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎΡΡ‚ΡŒΡŽ Π² выявлСнии синовитов Π² пСрифСричСских суставах, позволяСт ΠΎΡ†Π΅Π½ΠΈΠ²Π°Ρ‚ΡŒ Π΄ΠΈΠ½Π°ΠΌΠΈΠΊΡƒ заболСвания Π½Π° Ρ„ΠΎΠ½Π΅ лСчСния

    120 anniversary of the Dermatovenerology Chair of Sibirian State Medical University

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    A 120-years history of the Dermatovenerology Chair of SibirianStateMedicalUniversityis presented. The contribution of the scientists into the theory and practice in dermatovenerology and traning of specialists is described. The advances of the last 10 years are shown

    REFLECTION SPECTRA OF SKIN IN VITILIGO

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    Vitiligo is a disease with unknown etiology, which is characterized by skin depigmentation areas due to melanocyte death. Lack of clear understanding of pathogenic disease processes justifies the difficulty of choosing efficient treatment methods. Repigmentation is slow and not always complete. One of the key indicators in practical dermatology is objective assessment of skin cover condition for further diagnostics, definition of therapy and dynamics of the disease.The purpose of this study is to assess skin reflection spectrum in depigmentation areas, marginal layer and visible healthy skin before and after treatment of patients with vitiligo.21 patients having vitiligo were under observation; the patients were treated in the hospital of skin and venereal diseases of the Siberian State Medical University. The authors applied noninvasive method of spectrophotometry for the first time in order to study skin reflection spectrum of patients with vitiligo. Noninvasive medical spectrophotometry is based on dependence factor of integral optical properties of biological tissues and fluids in the conditions of homeostasis and in case of pathology. In order to assess the efficiency of skin disease treatment the patients were exposed to skin spectrophotometry before the beginning of the treatment and after the treatment itself with further measurements of the reflection spectrum integral criteria. The measurements were made in depigmentation area, on the boundary with healthy skin and in remote from depigmentation area of healthy skin.Obtained results indicate the difference of skin reflection spectra in the areas under investigation. Moreover, positive dynamics of the treatment associated with the decrease in the value of reflection spectrum integral criteria in the diseased area. There were no statistically important differences of the integral criteria, calculated based on measurement results of reflection spectra on the boundary of depigmentation area before and after treatment. Most likely this is related to active processes of repigmentation in the skin in the course of the treatment.For detailed study of identified phenomena there is a need for thorough study and expansion of the list of dermatologic diseases

    Opportunities of modern methods of radiodiagnosis for psoriatic arthritis

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    The comparative evaluation of modern imaging methods gives evidence of great opportunities of both MRT and US in the detection of structural alterations of joints at psoriatic arthritis. The key role is assigned to ultrasonography which has proved to be highly sensitive in the disclosure of peripheral joint synovitis and allows the follow-up during the treatment course
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