71 research outputs found
Phase imaging systems for measurement of plasma density contours
During recent years, there has been considerable interest in obtaining spatially localized time resolved density measurements in fusion plasmas. However, the study of such phenomena requires many channels of information on a scale much finer than available with current discrete chordal view multichannel interferometers. These problems can be overcome by imaging an expanded probe beam occupying the entire plasma port crosssection onto a linear detector array [1], thereby significantly reducing the number of optical components and hence the cost and complexity of the system compared with a comparable discrete chord multichannel interferometer. Other more fundamental advantages of the imaging technique include compensation for phase errors due to plasma refraction, whilst the diffraction limited system resolution (typically ≃ 1cm for FIR probe wavelengths) allows the use of many detector channels for high spatial sampling rates. and hence accurate reconstruction of the density profiles
Optical BVI Imaging and HI Synthesis Observations of the Dwarf Irregular Galaxy ESO 364-G 029
As part of an effort to enlarge the number of well-studied Magellanic-type
galaxies, we obtained broadband optical imaging and neutral hydrogen radio
synthesis observations of the dwarf irregular galaxy ESO 364-G 029. The optical
morphology characteristically shows a bar-like main body with a one-sided
spiral arm, an approximately exponential light distribution, and offset
photometric and kinematic centers. The HI distribution is mildly asymmetric
and, although slightly offset from the photometric center, roughly follows the
optical brightness distribution, extending to over 1.2 Holmberg radii (where
mu_B = 26.5 mag/arcsec^2). In particular, the highest HI column densities
closely follow the bar, one-arm spiral, and a third optical extension. The
rotation is solid-body in the inner parts but flattens outside of the optical
extent. The total HI flux F_HI = 23.1 pm 1.2 Jy km/s, yielding a total HI mass
M_HI= (6.4 pm 1.7) x 10^8 Msun (for a distance D = 10.8 pm 1.4 Mpc) and a total
HI mass-to-blue-luminosity ratio M_HI/L_B = (0.96 pm 0.14) Msun / Lsun,B
(distance independent). The HI data suggest a very complex small-scale HI
structure, with evidence of large shells and/or holes, but deeper observations
are required for a detailed study. Follow-up observations are also desirable
for a proper comparison with the Large Magellanic Cloud, where despite an
optical morphology very similar to ESO 364-G 029 the HI bears little
resemblance to the optical.Comment: 10 pages, 11 figures, accepted by A&
The DESiGN trial (DEtection of Small for Gestational age Neonate), evaluating the effect of the Growth Assessment Protocol (GAP): study protocol for a randomised controlled trial.
BACKGROUND: Stillbirth rates in the United Kingdom (UK) are amongst the highest of all developed nations. The association between small-for-gestational-age (SGA) foetuses and stillbirth is well established, and observational studies suggest that improved antenatal detection of SGA babies may halve the stillbirth rate. The Growth Assessment Protocol (GAP) describes a complex intervention that includes risk assessment for SGA and screening using customised fundal-height growth charts. Increased detection of SGA from the use of GAP has been implicated in the reduction of stillbirth rates by 22%, in observational studies of UK regions where GAP uptake was high. This study will be the first randomised controlled trial examining the clinical efficacy, health economics and implementation of the GAP programme in the antenatal detection of SGA. METHODS/DESIGN: In this randomised controlled trial, clusters comprising a maternity unit (or National Health Service Trust) were randomised to either implementation of the GAP programme, or standard care. The primary outcome is the rate of antenatal ultrasound detection of SGA in infants found to be SGA at birth by both population and customised standards, as this is recognised as being the group with highest risk for perinatal morbidity and mortality. Secondary outcomes include antenatal detection of SGA by population centiles, antenatal detection of SGA by customised centiles, short-term maternal and neonatal outcomes, resource use and economic consequences, and a process evaluation of GAP implementation. Qualitative interviews will be performed to assess facilitators and barriers to implementation of GAP. DISCUSSION: This study will be the first to provide data and outcomes from a randomised controlled trial investigating the potential difference between the GAP programme compared to standard care for antenatal ultrasound detection of SGA infants. Accurate information on the performance and service provision requirements of the GAP protocol has the potential to inform national policy decisions on methods to reduce the rate of stillbirth. TRIAL REGISTRATION: Primary registry and trial identifying number: ISRCTN 67698474 . Registered on 2 November 2016
Stochastic Gravity: Theory and Applications
Whereas semiclassical gravity is based on the semiclassical Einstein equation
with sources given by the expectation value of the stress-energy tensor of
quantum fields, stochastic semiclassical gravity is based on the
Einstein-Langevin equation, which has in addition sources due to the noise
kernel. In the first part, we describe the fundamentals of this new theory via
two approaches: the axiomatic and the functional. In the second part, we
describe three applications of stochastic gravity theory. First, we consider
metric perturbations in a Minkowski spacetime, compute the two-point
correlation functions of these perturbations and prove that Minkowski spacetime
is a stable solution of semiclassical gravity. Second, we discuss structure
formation from the stochastic gravity viewpoint. Third, we discuss the
backreaction of Hawking radiation in the gravitational background of a black
hole and describe the metric fluctuations near the event horizon of an
evaporating black holeComment: 100 pages, no figures; an update of the 2003 review in Living Reviews
in Relativity gr-qc/0307032 ; it includes new sections on the Validity of
Semiclassical Gravity, the Stability of Minkowski Spacetime, and the Metric
Fluctuations of an Evaporating Black Hol
Origin of Galactic and Extragalactic Magnetic Fields
A variety of observations suggest that magnetic fields are present in all
galaxies and galaxy clusters. These fields are characterized by a modest
strength (10^{-7}-10^{-5} G) and huge spatial scale (~Mpc). It is generally
assumed that magnetic fields in spiral galaxies arise from the combined action
of differential rotation and helical turbulence, a process known as the
alpha-omega dynamo. However fundamental questions concerning the nature of the
dynamo as well as the origin of the seed fields necessary to prime it remain
unclear. Moreover, the standard alpha-omega dynamo does not explain the
existence of magnetic fields in elliptical galaxies and clusters. The author
summarizes what is known observationally about magnetic fields in galaxies,
clusters, superclusters, and beyond. He then reviews the standard dynamo
paradigm, the challenges that have been leveled against it, and several
alternative scenarios. He concludes with a discussion of astrophysical and
early Universe candidates for seed fields.Comment: 67 pages, 17 figures, accepted for publication in Reviews of Modern
Physic
De novo formed satellite DNA-based mammalian artificial chromosomes and their possible applications
Impact of COVID-19 on cardiovascular testing in the United States versus the rest of the world
Objectives: This study sought to quantify and compare the decline in volumes of cardiovascular procedures between the United States and non-US institutions during the early phase of the coronavirus disease-2019 (COVID-19) pandemic.
Background: The COVID-19 pandemic has disrupted the care of many non-COVID-19 illnesses. Reductions in diagnostic cardiovascular testing around the world have led to concerns over the implications of reduced testing for cardiovascular disease (CVD) morbidity and mortality.
Methods: Data were submitted to the INCAPS-COVID (International Atomic Energy Agency Non-Invasive Cardiology Protocols Study of COVID-19), a multinational registry comprising 909 institutions in 108 countries (including 155 facilities in 40 U.S. states), assessing the impact of the COVID-19 pandemic on volumes of diagnostic cardiovascular procedures. Data were obtained for April 2020 and compared with volumes of baseline procedures from March 2019. We compared laboratory characteristics, practices, and procedure volumes between U.S. and non-U.S. facilities and between U.S. geographic regions and identified factors associated with volume reduction in the United States.
Results: Reductions in the volumes of procedures in the United States were similar to those in non-U.S. facilities (68% vs. 63%, respectively; p = 0.237), although U.S. facilities reported greater reductions in invasive coronary angiography (69% vs. 53%, respectively; p < 0.001). Significantly more U.S. facilities reported increased use of telehealth and patient screening measures than non-U.S. facilities, such as temperature checks, symptom screenings, and COVID-19 testing. Reductions in volumes of procedures differed between U.S. regions, with larger declines observed in the Northeast (76%) and Midwest (74%) than in the South (62%) and West (44%). Prevalence of COVID-19, staff redeployments, outpatient centers, and urban centers were associated with greater reductions in volume in U.S. facilities in a multivariable analysis.
Conclusions: We observed marked reductions in U.S. cardiovascular testing in the early phase of the pandemic and significant variability between U.S. regions. The association between reductions of volumes and COVID-19 prevalence in the United States highlighted the need for proactive efforts to maintain access to cardiovascular testing in areas most affected by outbreaks of COVID-19 infection
- …