6 research outputs found
PEG length of PLA-PEG nanoparticles modulates nanoparticle interactions with brain endothelial cells
Get PDFSynthesis of PLA-b-PEG Multiblock Copolymers for Stealth Drug Carrier Preparation
No full textAn efficient method of preparing biodegradable and biocompatible multiblock copolymers from lactic acid and polyethylene glycol is proposed
Effect of Polymer Architecture on Surface Properties, Plasma Protein Adsorption, and Cellular Interactions of Pegylated Nanoparticles
No full textAFM study of a New Carrier Based on PLA and Salen Copolymers for Gene Therapy
No full textThe aim of this study was to synthesize novel biodegradable charged polymers to be used in DNA complexation for genetic delivery in different diseases. A new copolymer of PLA and complexed Schiff bases was synthesized in a several steps. This copolymer will be used as a nanocarrier. Also, AFM comparative studies in tapping mode were performed; on cationic copolymer and on PLA-Schiff base copolymer, on non-oriented and oriented film and on the DNA-cationic complex. The results indicated a difference in the topology and on phase picture of AFM film with or without cationic charge
