537 research outputs found
Near‐infrared fluorescent image‐guided lymph node dissection compared with locoregional lymphadenectomies in dogs with mast cell tumours
Objectives: Near-infrared fluorescent imaging has been described for intraoperative mapping of the draining lymph nodes in human cancer and canine oral tumours. The aim of this study was to retrospectively describe the results of lymphadenectomies in dogs with mast cell tumours treated either by standard unguided locoregional lymph node dissection or near-infrared fluorescent image-guided lymph node dissection.
Methods: Medical records between 2012 and 2020 were reviewed for dogs that were presented for surgical resection of mast cell tumours with concurrent lymphadenectomy either with (near-infrared fluorescent image-guided lymph node dissection) or without near-infrared fluorescence image guidance (lymph node dissection). The number and location of lymph nodes planned for surgical dissection and actually dissected nodes, presence of metastases and perioperative complications were recorded.
Results: Thirty-five patients underwent near-infrared fluorescent image-guided lymph node dissection, and 43 lymph node dissections. The number of nodes preoperatively planned for resection were 70 and 68, respectively. Fifty-eight of those (83%) were identified during near-infrared fluorescent image-guided lymph node dissection procedures, compared with 50 (74%) during lymph node dissection. near-infrared fluorescent image-guided lymph node dissection resulted in resection of additional fluorescent nodes not corresponding to locoregional nodes in 15 of 35 dogs. Using near-infrared fluorescent image-guided lymph node dissection, we identified at least one metastatic node in 68% of dogs (24 of 35) compared with 33% (14 of 43) when lymph node dissection was used without imaging. No complications related to near-infrared fluorescent imaging were reported.
Clinical significance: The present study suggests that near-infrared imaging is a promising technique for intraoperative detection of the draining lymph nodes in dogs with mast cell tumours. Further validation of the technique is required to assess if near-infrared fluorescent imaging can detect the true sentinel lymph node
Recent Decisions
Comments on recent decisions by Frank J. Duda, J. Russell Bley, Lawrence J. Gallick, Louis P. Pfeiler, and Charles P. Sacher
Characterization of the glass transition in vitreous silica by temperature scanning small-angle X-ray scattering
The temperature dependence of the x-ray scattering in the region below the
first sharp diffraction peak was measured for silica glasses with low and high
OH content (GE-124 and Corning 7980). Data were obtained upon scanning the
temperature at 10, 40 and 80 K/min between 400 K and 1820 K. The measurements
resolve, for the first time, the hysteresis between heating and cooling through
the glass transition for silica glass, and the data have a better signal to
noise ratio than previous light scattering and differential thermal analysis
data. For the glass with the higher hydroxyl concentration the glass transition
is broader and at a lower temperature. Fits of the data to the
Adam-Gibbs-Fulcher equation provide updated kinetic parameters for this very
strong glass. The temperature derivative of the observed X-ray scattering
matches that of light scattering to within 14%.Comment: EurophysicsLetters, in pres
Experimentelle und theoretische Untersuchungen zur gasdynamischen Trennung von Uranhexafluorid und Helium in Trennduesenanlagen zur Anreicherung von Uran-235
Minimierung von Trennleistungsverlusten beim Betrieb einer Trennduesenanlage mit Doppelumlenksystemen zur Anreicherung von Uran-235
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