7 research outputs found
Double Injustice, Double Trauma: The Effects of Acquittal of Offenders Upon the Families of Victims of Homicide
Cancer prevention: a resource to support local action in delivering the NHS cancer plan
Aimed at people working in primary care trusts, cancer networks, strategic health authorities, local authorities and partner agencies, to assist them in their local strategic planning and delivery of initiatives to prevent cancer. Makes recommendations for action based on the evidence of what works best in tackling the key cancer risk factors highlighted in the NHS cancer plan
Exploratory Chemometric Analysis on Source of Origin and Cultivar of Chinese Wolfberries Using Liquid ChromatographâMass Spectrometric and Flow Injection Mass Spectrometric (FIMS) Fingerprints
Phenolic extracts from whole wheat biofortified bread dampen overwhelming inflammatory response in human endothelial cells and monocytes: major role of VCAM-1 and CXCL-10
Phenolic Compounds in Wheat Kernels: Genetic and Genomic Studies of Biosynthesis and Regulations
Whole wheat grains are an important source of bioactive components,
particularly of phenolic acids and flavonoids. Due to the health-promoting effects of
these phenolics, nowadays, the increase of their content in mature kernels is of great
interest and a potential target for wheat breeding programs. The biogenesis of phenolics
occurs through the general phenylpropanoid pathway, which is ubiquitous in
plant cell walls and leads to the synthesis of secondary metabolites that are involved
in plant defence and structural support. This chapter reviews the current knowledge
in phenylpropanoid chemistry, and the genetic and molecular basis for the biosynthesis
of phenolic acids and anthocyanins in wheat grains. Also, advances in assessing
genetic variation in the content and composition of these components in wheat
germplasm are reviewed, including the effects of different environmental conditions
on their accumulation in mature kernels. The recent, ongoing genomic studies are
reviewed providing updates on quantitative trait loci and genes involved in the synthesis
and accumulation of phenolics in wheat kernels. Finally, the promise and
limitations of breeding programs to potentially develop wheat cultivars rich in phenolic
components are discussed