COUROUPITA GUIANENSIS: THE RESERVOIR OF MEDICINAL COMPOUNDS OF HUMAN WELFARE

ABSTRACTMedicinal plants play a role in the traditional form of providing relief to several diseases. Couroupita guianensis is also a type of medicinal plantwhich has antibacterial, antimycobacterial, antimicrobial, antioxidant, antitumor, antiulcer, antinociceptive, anthelmintic, antifertility, and antifungalactivities. The chemical constituent of C. guianensis such as indirubin serves as an antibacterial and antifungal agent because it particularly curesfungal diseases. It is active for the treatment of chronic myelocytic leukemia. The extract of isatin from the flower of C. guianensis is also a chemicalcomponent that has been used as prophylactic agent, prevents free radial-induced cancer, acts as a chemotherapeutic agent to kill cancer cells, and ithas antioxidant (act as major defense) and anticancer activities against human promylocytic leukemia 60 cells. The extract of chloroform of fruit ofC. guianensis shows good antimicrobial activity but low antimycobacterial activity. The plant extract of C. guianensis is equipotent to standard drugssuch as paracetamol in its analgesic activity and indomethacin in its anti-inflammatory activity.Keywords: Couroupita quianensis, Antibacterial activity, Anti tumor activity, Antioxidant activity, Anti biofil

Flaxseed supplementation improved insulin resistance in obese glucose intolerant people: a randomized crossover design

<p>Abstract</p> <p>Background</p> <p>Obesity leads to an increase in inflammation and insulin resistance. This study determined antioxidant activity of flaxseed and its role in inflammation and insulin resistance in obese glucose intolerant people.</p> <p>Methods</p> <p>Using a randomized crossover design, nine obese glucose intolerant people consumed 40 g ground flaxseed or 40 g wheat bran daily for 12 weeks with a 4-week washout period. Plasma inflammation biomarkers (CRP, TNF-α, and IL-6), glucose, insulin, and thiobaribituric acid reactive substance (TBARS) were measured before and after of each supplementation.</p> <p>Results</p> <p>Flaxseed supplementation decreased TBARS (p = 0.0215) and HOMA-IR (p = 0.0382). Flaxseed or wheat bran supplementation did not change plasma inflammatory biomarkers. A positive relationship was found between TBARS and HOMA-IR (r = 0.62, p = 0.0003).</p> <p>Conclusions</p> <p>The results of the study weakly support that decreased insulin resistance might have been secondary to antioxidant activity of flaxseed. However, the mechanism(s) of decreased insulin resistance by flaxseed should be further determined using flaxseed lignan.</p

Aulacophora foveicollis, a natural diet to entomopathogenic fungus, Beauveria bassiana

The red pumpkin beetle (RPB), Aulacophora foveicollis, becomes a notable thread to cucurbitaceous family. The present investigation studied the efficiency of Beauveria bassiana (B8) isolate against RPB. The results revealed that, they secured lowest lethal concentration (9 × 103) besides stunning growth over treated adult RPB. The gradual increase and dispersal of hyphea from thoracic region of the insect to all over the body was studied clearly in the present investigation. From this study, it was strongly recommended that, the B. bassiana would be a promising biocontrol agent and suggested for the field RPB management