In vitro evaluation of anticancer property of anthocyanin extract from Musa acuminate bract

Anthocyanins are potent anticarcinogenic properties against several cancers thus demonstrating potential for cancer prevention. In the present study, we have investigated the chemopreventive effects of anthocyanin extracted from Musa acuminata bract against human breast cancer cell line (MCF-7). Acidified methanolic extracts from Musa acuminata bract has shown 12.24% inhibition at 1000µg/ml concentration against MCF-7 cell line. Results indicated that anthocyanin from Musa acuminata bract extracts had strong antiproliferative activity against MCF-7 cell lines at varying concentration. These results encourage the bioactive constituents as chemopreventive agents for human breast cancer

Evaluation of Antiproliferative Activity of Red Sorghum Bran Anthocyanin on a Human Breast Cancer Cell Line (MCF-7)

Breast cancer is a leading cause of death in women worldwide both in the developed and developing countries. Thus effective treatment of breast cancer with potential antitumour drugs is important. In this paper, human breast cancer cell line MCF-7 has been employed to evaluate the antiproliferative activity of red sorghum bran anthocyanin. The present investigation showed that red sorghum bran anthocyanin induced growth inhibition of MCF-7 cells at significant level. The growth inhibition is dose dependent and irreversible in nature. When MCF-7 cells were treated with red sorghum bran anthocyanins due to activity of anthocyanin morphological changes were observed. The morphological changes were identified through the formation of apoptopic bodies. The fragmentation by these anthocyanins on DNA to oligonuleosomal-sized fragments, is a characteristic of apoptosis, and it was observed as concentration-dependent. Thus, this paper clearly demonstrates that human breast cancer cell MCF-7 is highly responsive by red sorghum bran anthocyanins result from the induction of apoptosis in MCF-7 cells

The effect of light, temperature, ph on stability of anthocyanin pigments in Musa acuminata bract

The anthocyanin pigment was extracted from Musa acuminata bract using the acidified methanol. The extracted anthocyanin pigments then were exposed to number of environmental conditions, which could destabilize the anthocyanin molecules. These environmental conditions were included fourteen different pHs, various temperatures and presence or absence of light. The temperature stability of the anthocyanin extract was calculated by reaction velocity constants (k) as well as the half-life time (t1/2). The results of the study showed that increasing in pH, temperature or exposure to light is able to spoil the anthocyanin molecule. Copigmentation of anthocyanin resulting in increase in both hypochromic effects and bathochromic shifts. Musa acuminata bract anthocyanin extract was more stable at pH 5.1 and 6.0, temperature at 20° C and 30° C both in the presence and absence of light. This characteristic differs from other anthocyanins. This property could facilitate its application as a natural food colorant

Genetic Enhancement Perspectives and Prospects for Grain Nutrients Density

Diet-induced micronutrient malnutrition continues to be a major challenge globally, especially in the developing world. With the ever-increasing population, it becomes a daunting task to feed millions of mouths with nutritious food. It is time to reorient agricultural systems to produce quality food to supply the calorie and nutrient requirements needed by the human body. Biofortification is the process of improving micronutrients density by genetic means. It is cheaper and sustainable and complements well with the nutrient supplementation and fortification— the short-term strategies that are currently deployed to address the micronutrient malnutrition. Sorghum is one of the important food crops globally, adapted to semi-arid tropics, and there is increased awareness on its nutritional importance. Further, there is great opportunity to improve sorghum for nutritional quality. This chapter deals about the genetic enhancement perspectives and prospects for improving the nutritional quality with main emphasis on grain micronutrient density in sorghum

Secure E-Pay System Using Steganography and Visual Cryptography

Today’s internet world is highly prone to various online attacks, of which the most harmful attack is phishing. The attackers host the fake websites which are very similar and look alike. We propose an image based authentication using steganography and visual cryptography to prevent phishing. This paper presents a secure steganographic technique for true color (RGB) images and uses Discrete Cosine Transform to compress the images. The proposed method hides the secret data inside the cover image. The use of visual cryptography is to preserve the privacy of an image by decomposing the original image into two shares. Original image can be identified only when both qualified shares are simultaneously available. Individual share does not reveal the identity of the original image. Thus, the existence of the secret message is hard to be detected by the RS steganalysis