259 research outputs found
Mapping of the Influenza-A Hemagglutinin Serotypes Evolution by the ISSCOR Method
Analyses and visualizations by the ISSCOR method of influenza virus
hemagglutinin genes of different A-subtypes revealed some rather striking
temporal relationships between groups of individual gene subsets. Based on
these findings we consider application of the ISSCOR-PCA method for analyses of
large sets of homologous genes to be a worthwhile addition to a toolbox of
genomics - allowing for a rapid diagnostics of trends, and ultimately even
aiding an early warning of newly emerging epidemiological threats.Comment: 26 pages with figures (Figs. 1-4 in the main text, and Figs. S1-S5 in
supplementary materials
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