Vulnerability of public buildings subjected to earthquake by finite element modelling

Tremors in Peninsular Malaysia and East Malaysia due to Sumatra and Philippine earthquakes have been reported several times. Engineers are concerned of the seismic vulnerability of public buildings due to lack of earthquake consideration in Malaysia’s building design procedure. This study addresses the vulnerability of public buildings in Malaysia subjected to earthquakes from Sumatra and Philippines. A case study has been conducted on low rise to medium rise reinforced concrete buildings, which are mostly categorized as moment resisting frames. The buildings are analyzed using Finite Element Modeling (FEM) under different types of analyses including Free Vibration Analysis (FVA), and Time History Analysis (THA) considering low to medium earthquake intensities. The study indicates that more than 50% of the buildings produced dynamic amplification factors of slightly more than one indicating not much of a dynamic response to the buildings. The performances of the structure are shown by the yield point at beam-column connections where the internal forces at beam elements exceed the design capacity of the beams. In the non-linear analysis, the largest damage index is still under the intermediate level where no structural damage is indicated, but some non-structural damage are expected

1′′-Benzyl-1′-methyl-4′-(naphthalen-1-yl)naphthalene-2-spiro-3′-pyrrolidine-2′-spiro-3′′-indoline-1,2′′-dione

In the title compound, C38H32N2O2, the pyrrolidine ring adopts an envelope conformation, whereas the cyclo­hexa­none ring in the tetra­hydro­naphthalene fused-ring system adopts a half-chair conformation. The benzyl ring is oriented at an angle of 67.1 (1)° with respect to the naphthyl ring system. Four intra­molecular C—H⋯O close contacts and C—H⋯π inter­action are observed. In the crystal, mol­ecules associate via C—H⋯O hydrogen bonds, forming a C(12) chain motif along the ac plane

1′,1′′-Dimethyl-4′-(naphthalen-1-yl)-1,2,3,4-tetra­hydro­naphthalene-2-spiro-3′-pyrrolidine-2′-spiro-3′′-indoline-1,2′′-dione

In the title compound, C32H28N2O2, the pyrrolidine ring adopts an envelope conformation, whereas the cyclo­hexa­none ring in the tetra­hydro­naphthalene fused-ring system adopts a half-chair conformation. The oxindole ring system is oriented at an angle of 48.2 (1)° with respect to the naphthyl ring system. An intra­molecular C—H⋯O close contact is observed. In the crystal, mol­ecules associate via two C—H⋯O hydrogen bonds, forming R 2 2(14) and R 2 2(10) dimers

Wideband Josephson Parametric Isolator

The cryogenic hardware required to build a superconducting qubit based quantum computer demands a variety of microwave components. These elements include microwave couplers, filters, amplifiers, and circulators/isolators. Traditionally implemented as discrete components, integration of this peripheral hardware, in an effort to reduce overall footprint, thermal load, and added noise, is a key challenge to scaling modern quantum processors with qubit counts climbing over the 100+ mark. Ferrite--based microwave isolators, generally employed in the readout chain to decouple qubits and resonators from readout electronics, persist as one of the volumetrically largest devices still utilized as discrete components. Here we present an alternative two--port isolating integrated circuit derived from the DC Superconducting Quantum Interference Device (DC--SQUID). Non--reciprocal transmission is achieved using the three--wave microwave mixing properties of a flux-modulated DC--SQUID. We show that when multiple DC--SQUIDs are embedded in a multi--pole admittance inverting filter structure, the three--wave mixing derived from the flux pumping of the DC--SQUIDs can provide directional microwave power flow. For a three--pole filter device, we experimentally demonstrate a directionality greater than 15 dB over a 600 MHz bandwidth.Comment: 16 pages, 10 figure

1′-Methyl-4′-(1-naphth­yl)-1′′,2′′,3′′,4′′-tetra­hydro­indane-2-spiro-2′-pyrrolidine-3′-spiro-2′′-naphthalene-1,3,1′′-trione

In the title compound, C32H25NO3, the pyrrolidine ring adopts an envelope conformation, whereas the cyclo­hexa­none ring in the tetra­hydro­naphthalene fused-ring system adopts a half-chair conformation. The indanedione unit is oriented at an angle of 58.9 (1)° with respect to the naphthyl ring system. Three intra­molecular C—H⋯O close contacts and an intra­molecular C—H⋯π inter­action are observed. In the crystal, mol­ecules associate via C—H⋯O hydrogen bonds, forming a helical chain with a C(10) motif along the b axis

Non-invasive evaluation of myocardial fibrosis: implications for the clinician

The presence and extent of myocardial fibrosis are key determinants of response to treatment and prognosis in a number of cardiac conditions. Until recently, myocardial fibrosis could only be detected ante mortem by endomyocardial biopsy, which is associated with procedural risk and sampling error. The development of novel cardiac imaging techniques and serum assays now permits the accurate detection and quantification of myocardial fibrosis. These have yielded new insights into disease prognosis and response to treatment.Darryl P. Leong, Per Lav Madsen, Joseph B. Selvanayaga

(1,2,3,4-Tetra­hydro­isoquinoline-2-carbo­dithio­ato-κ2 S,S′)(thio­cyanato-κN)(tri­phenyl­phosphane)nickel(II)

The NiII atom in the mononuclear title compound, [Ni(C10H10NS2)(NCS)(C18H15P)], exists within a S2PN donor set that defines a distorted square-planar geometry. A significant asymmetry in the Ni—S bond lengths support the less effective trans effect of SCN− over PPh3

6′-Amino-3′-methyl-2-oxo-1′-phenyl-1′,3a′,4′,7a′-tetra­hydrospiro­[1H-indole-3(2H),4′-pyrano[2,3-d]pyrazole]-5′-carbonitrile

In the crystal structure of the title compound, C21H15N5O2, the planar indolone unit and the pyran ring are almost perpendicular to each other [dihedral angle = 89.41 (2)°], and the pyrazole and phenyl rings are oriented at an angle of 25.74 (1)°. The mol­ecular packing is stabilized by inter- and intra­molecular C—H⋯O, N—H⋯O and C—H⋯π hydrogen bonds