7 research outputs found
VLADINOL F, NEOLIGNAN COMPOUND FROM THE STEM BARK OF Dryobalanops oblongifolia (DIPTEROCARPACEAE) AND ANTIPLASMODIAL ACTIVITY
Get PDFDrybalanops oblongifolia known as kayu kapur is a plant member of Dipterocarpaceae family. A neolignan, vladinol F, was successfully isolated from the dissolved fraction in acetone-ether of Dryobalanops oblongifolia stem bark. The chemical structure's determination was done based on an analysis of UV-Vis, NMR, and MS spectra and a comparison with the reference. In vitro test of this compound against Plasmodium falciparum 3D7 showed that IC50 value was 3.51 μg/mL
RbAp48 is essential for viability of vertebrate cells and plays a role in chromosome stability
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