381 research outputs found
Parrot damage to bluegum tree crops : a review of the problem and possible solutions
Damage to Bluegum (Eucalyptus globulus) tree crops by the Twenty-eight Parrot (Barnardius zonarius) is emerging problem which could threaten the viability of the infant Bluegum industry in south-western Australia. The parrots strip bark from the lead shoot of the Bluegums causing the shoots to break off. Consequently lateral shoots develop resulting in deformed (bent or multi-stem) trees unsuited to harvest and utilisation.Indications that the reason Twenty-eight Parrots strip bark from Bluegum is to obta behaviour\u27 and hence the damage may also develop in areas where it is absent or uncommon now. Currently the zone of worst damage includes around 20% of the total area suitable for Bluegum planting in south-west Australia.There is a \u27critical period\u27 for controlling parrot damage. At monitoring sites this was found to start in March of the first year after planting and end around July of the second year after planting
The Basis of VCP-Mediated Degeneration: Insights From a Drosophila Model of Disease
Valosin-containing protein (VCP) is a highly conserved molecular chaperone that regulates a wide array of essential cellular processes. Mutations in VCP are causative of degenerative disease that can affect muscle, brain and bone. Despite VCP being implicated in many major pathways in the cell, the mechanism of disease pathogenesis is unknown. To gain insight into the degeneration associated with mutations in VCP, we developed and characterized a Drosophila model of disease that recapitulated VCP mutation-dependent toxicity. VCP is involved in a diverse array of activities, many of which we may not know. Therefore we employed an unbiased genetic screening method that has the potential to uncover unanticipated pathways affected in the disease. Using this approach, we identified four proteins that dominantly suppressed degeneration; one of which was Ube4b, one of the many known ancillary proteins that bind to VCP and determine its function. The three remaining dominant modifiers identified were all RNA-binding proteins including TBPH, the Drosophila orthologue of TAR (trans-activating response region) DNA-binding protein (TDP-43). TDP-43 has been identified as a major component of the ubiquitinated inclusions characteristic of an emerging spectrum of proteinopathies, including degeneration associated with VCP mutations. Redistribution of TDP-43 from the nucleus to the cytoplasm has been demonstrated in these proteinopathies but the significance of this was unknown. Here we demonstrated that TDP-43 and VCP interact genetically and disease-causing VCP mutations led to redistribution of TDP-43 to the cytoplasm in vitro and in vivo, replicating the major pathology observed in TDP-43 proteinopathies. Furthermore, we demonstrated that TDP-43 redistribution is sufficient to induce cytotoxicity. Together our results show that degeneration associated with VCP mutations is mediated, in part, by toxic gain of function of TDP-43 in the cytoplasm where its redistribution is possibly due to the altered binding repertoire of VCP. This work acts to further our understanding of the pathogenic mechanism of, not only VCP-related disease but also a broad array of TDP-43 proteinopathies that include frontotemporal dementia, inclusion body myopathies and amyotrophic lateral sclerosis
The use of historical accounts of species distribution to suggest restoration targets for UK upland mires within a ‘moorland’ landscape
Using contemporary accounts of vegetation in the South Pennine landscape of northern England from the late 18th Century to the present day, we describe the degradation and subsequent partial recovery of these upland mire systems in terms of their vegetation biodiversity. The historical sources highlight several species that were once common on these peatlands but which do not currently feature as positive indicator species in monitoring or restoration programmes. The use of archival sources may provide additional evidence that complements palaeoecological data when setting restoration targets. For example, the historical accounts support the palaeoecological timeline for the disappearance of Sphagnum from these landscapes. As a step toward a possible expanded set of targets for restoration works, we suggest an extended list of positive indicator species for the South Pennines which could also be applicable elsewhere in the UK. These include species such as lesser twayblade (Neottia cordata) and the club mosses (Lycopodiaceae), which were noted to be common in the 18th and 19th centuries, but which had become rare by the early 20th century. We highlight changes in land ownership and land use through the process of enclosure, as well as indirect effects from industrialisation, as the dominant interacting drivers of vegetation change
Determining consumer expectations, attitudes and buying behaviour towards “low input” and organic foods
This paper reviews the first results and achievements of the QLIF SP1 “Determining consumer expectations and attitudes towards organic/low input food quality and safety”. The paper aims to illustrate the array of methodologies used and to discuss the ongoing research in light of the first results
Tortious Necessity; The Privileged Defense
The similarities between the laws of torts in the United States of America and England enable one to make an interesting comparison between the two sets of rules applicable to the general defense of necessity. Although both tort systems are derivatives to a greater or lesser extent of the English common law, they have inevitably developed their own individual jurisprudence over the years. Concepts have been refined and extended to produce significant and curious differences which provide an interesting exercise in legal forensic. The similarities of the two tort systems make a comparative study possible, and the differences provide the justification for the analysis
Policy instruments in the Common Agricultural Policy
Policy changes in the Common Agricultural Policy (CAP) can be explained in terms of the exhaustion and long-term contradictions of policy instruments. Changes in policy instruments have reoriented the policy without any change in formal Treaty goals. The social and economic efficacy of instruments in terms of evidence-based policy analysis was a key factor in whether they were delegitimized. The original policy instruments were generally dysfunctional, but reframing the policy in terms of a multifunctionality paradigm permitted the development of more efficacious instruments. A dynamic interaction takes place between the instruments and policy informed by the predominant discourses
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The effect of drought on dissolved organic carbon (DOC) release from peatland soil and vegetation sources
Drought conditions are expected to increase in frequency and severity as the climate changes, representing a threat to carbon sequestered in peat soils. Downstream water treatment works are also at risk of regulatory compliance failures and higher treatment costs due to the increase in riverine dissolved organic carbon (DOC) often observed after droughts. More frequent droughts may also shift dominant vegetation in peatlands from Sphagnum moss to more drought tolerant species. This paper examines the impact of drought on the production and treatability of DOC from four vegetation litters (Calluna vulgaris, Juncus effusus, Molinia caerulea and Sphagnum spp.) and a peat soil. We found that mild droughts caused a 39.6 % increase in DOC production from peat and that this DOC was harder to remove by conventional water treatment processes (coagulation/flocculation). Drought had no effect on DOC production from vegetation litters, however large variation was observed between typical peatland species (Sphagnum and Calluna) and drought tolerant grassland species (Juncus and Molinia), with the latter producing more DOC per unit weight. This would therefore suggest the increase in riverine DOC often observed post-drought is due entirely to soil microbial processes and DOC solubility rather than litter-layer effects. Long term shifts in species diversity may, therefore, be the most important impact of drought on litter layer DOC flux, whereas more immediate effects are observed in peat soils. These results provide evidence in support of catchment management which increases the resilience of peat soils to drought, such as ditch-blocking to raise water-tables
Masculinity as Governance: police, public service and the embodiment of authority, c. 1700-1850
About the book: Public Men offers an introduction to an exciting new field: the history of masculinities in the political domain and will be essential reading for students and specialists alike with interests in gender or political culture. By building upon new work on gender and political culture, these new case studies explore the gendering of the political domain and the masculinities of the men who have historically dominated it. As such, Public Men is a major contribution to our understanding of the history of Britain between the Eighteenth and the Twentieth centuries
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Sensitivity of peatland litter decomposition to changes in temperature and rainfall
Changes to climate are projected over the next 50 years for many peatland areas. As decomposition of peatforming vegetation is likely to be intrinsically linked to these changes in climate, a clear understanding of climate-peat dynamics is required. There is concern that increased temperature and decreased precipitation could increase the rate of decomposition and put the carbon sink status of many peatlands at risk, yet few studies
have examined the impact of both climatic factors together. To better understand the sensitivity of peatland decomposition to changes in both temperature and precipitation and their interaction, we conducted a shortterm
laboratory experiment in which plant litters and peat soil were incubated, in isolation, in a factorial design.
Treatments simulated baseline and projected climate averages derived from the latest UK climate change projections (UKCP09) for Exmoor, a climatically marginal peatland in SW England. Regular carbon dioxide flux
measurements were made throughout the simulation, as well as total mass loss and total dissolved organic carbon (DOC) leached. The largest effect on carbon loss in this multifactor experiment was from substrate, with
Sphagnum/peat releasing significantly less C in total during the experiment than dwarf shrubs/graminoids.
Climate effects were substrate specific, with the drier rainfall treatment increasing the DOC leaching from
Calluna, but decreasing it from Sphagnum. Partitioning between CO2 and DOC was also affected by climate, but
only for the peat and Sphagnum samples, where the future climate scenarios (warmer and drier) resulted in a
greater proportion of C lost in gaseous form. These results suggest that indirect effects of climate through
changes in species composition in peatlands could ultimately turn out to be more important for litter decomposition
than direct effects of climate change from increased temperatures and decreased rainfall
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