A synoptic-scale overview of the TOGA COARE intensive observing period November 1992 to February 1993 based on analyses from US operational global data assimilation systems

The operational global analyses from the two major U.S. numerical weather prediction centers, the Navy's Fleet Numerical Oceanography Center and the National Meteorological Center, are used to describe the synoptic-scale features of the 1 Nov. 1992 to 28 Feb. 1993 TOGA COARE intensive observing period (IOP). TOGA COARE is an international field experiment in which a large number of research scientists from the Goddard Laboratory for Atmospheres (Code 910) and the Laboratory for Hydrospheres (Code 970) participated. Two high-amplitude intraseasonal (30-60 day) oscillations passed through the TOGA COARE observational network located in the equatorial western Pacific. Associated with the oscillations were two 6-10 day periods of persistent westerly surface winds at the equator or 'westerly wind bursts.' These events are depicted through time series and time-longitude cross sections of divergence/velocity potential, surface winds, precipitation, ocean mixed-layer depth, and sea surface temperature. The high and low frequency components of the flow in which the intraseasonal oscillations were embedded are shown using seasonal, monthly, and 5-day averages of the surface, 850 and 200 mb winds, precipitation, and sea-level pressure, and a time-longitude cross section of tropical cyclone activity. Independent verification of precipitation comes from near real-time satellite estimates, and a reference climatology is given based on 9 years of ECMWF analyses. Daily 00 UTC analyses of surface winds and sea-level pressure for the entire western Pacific and Indian Ocean are provided to trace the evolution of individual synoptic events

Introduction of oral vitamin D supplementation and the rise of the allergy pandemic

The history of the allergy pandemic is well documented, enabling us to put the vitamin D hypothesis into its historical context. The purpose of this study is to compare the prevalence of rickets, vitamin D supply, and allergy prevalence at 50-year intervals by means of a retrospective analysis of the literature since 1880

Periodontal manifestations of systemic diseases and developmental and acquired conditions:consensus report of workgroup 3 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions

BACKGROUND A variety of systemic diseases and conditions can affect the course of periodontitis or have a negative impact on the periodontal attachment apparatus. Gingival recessions are highly prevalent and often associated with hypersensitivity, the development of caries and non-carious cervical lesions on the exposed root surface and impaired esthetics. Occlusal forces can result in injury of teeth and periodontal attachment apparatus. Several developmental or acquired conditions associated with teeth or prostheses may predispose to diseases of the periodontium. The aim of this working group was to review and update the 1999 classification with regard to these diseases and conditions, and to develop case definitions and diagnostic considerations. METHODS Discussions were informed by four reviews on 1) periodontal manifestions of systemic diseases and conditions; 2) mucogingival conditions around natural teeth; 3) traumatic occlusal forces and occlusal trauma; and 4) dental prostheses and tooth related factors. This consensus report is based on the results of these reviews and on expert opinion of the participants. RESULTS Key findings included the following: 1) there are mainly rare systemic conditions (such as Papillon-Lefevre Syndrome, leucocyte adhesion deficiency, and others) with a major effect on the course of periodontitis and more common conditions (such as diabetes mellitus) with variable effects, as well as conditions affecting the periodontal apparatus independently of dental plaque biofilm-induced inflammation (such as neoplastic diseases); 2) diabetes-associated periodontitis should not be regarded as a distinct diagnosis, but diabetes should be recognized as an important modifying factor and included in a clinical diagnosis of periodontitis as a descriptor; 3) likewise, tobacco smoking - now considered a dependence to nicotine and a chronic relapsing medical disorder with major adverse effects on the periodontal supporting tissues - is an important modifier to be included in a clinical diagnosis of periodontitis as a descriptor; 4) the importance of the gingival phenotype, encompassing gingival thickness and width in the context of mucogingival conditions, is recognized and a novel classification for gingival recessions is introduced; 5) there is no evidence that traumatic occlusal forces lead to periodontal attachment loss, non-carious cervical lesions, or gingival recessions; 6) traumatic occlusal forces lead to adaptive mobility in teeth with normal support, whereas they lead to progressive mobility in teeth with reduced support, usually requiring splinting; 7) the term biologic width is replaced by supracrestal tissue attachment consisting of junctional epithelium and supracrestal connective tissue; 8) infringement of restorative margins within the supracrestal connective tissue attachment is associated with inflammation and/or loss of periodontal supporting tissue. However, it is not evident whether the negative effects on the periodontium are caused by dental plaque biofilm, trauma, toxicity of dental materials or a combination of these factors; 9) tooth anatomical factors are related to dental plaque biofilm-induced gingival inflammation and loss of periodontal supporting tissues. CONCLUSION An updated classification of the periodontal manifestations and conditions affecting the course of periodontitis and the periodontal attachment apparatus, as well as of developmental and acquired conditions, is introduced. Case definitions and diagnostic considerations are also presented

Nucleic acids,

Bibliographical foot-notes.Mode of access: Internet

The European rescue of the Washington Consensus? EU and IMF lending to Central and Eastern European countries

The latest global financial crisis has allowed the International Monetary Fund (IMF) a spectacular comeback. But despite its notorious reputation as a staunch advocate of restrictive economic policies, the Fund has displayed less preference for austerity in recent crisis lending. Though widely welcomed as overdue, the IMF’s shift away from what John Williamson coined the ‘Washington Consensus’ was met with resistance from the European Union (EU) where it concerned Central and Eastern European (CEE) countries. The situation of hard-hit Hungary, Latvia, and Romania propelled unprecedented cooperation between the IMF and the EU, in which the EU has very actively promoted orthodox measures in return for loans. We argue that this represents a European rescue of the Washington Consensus. The case of Latvia is paradigmatic for the profound disagreements between an austerity-demanding EU and a less austere IMF. The IMF’s stance contradicts conventional wisdom about the organization as the guardian of economic orthodoxy. To solve this puzzle, we shed light on three complementary factors of (non)learning that have shaped the EU’s relations vis-à-vis CEE borrowing countries in comparison to the IMF’s: (1) a disadvantageous institutional setting; (2) vociferous creditor coalitions; (3) the precarious eurozone project

Relationship of the level of knowledge regarding essential intrapartum and newborn care and utilization of healthcare facilities of mothers 18-35 years old living in Barangay Zone 1, Dasmarinas City, Cavite in 2013 : a cohort study

This study utilized a cohort research design. Sixty six (66) mothers ages 18-35 years old were selected using simple random sampling and asked to answere a questionnaire adapted from Saving Newborn Lives: Care of the Newborn Training Guide by the Save the Children Federation published in 2005. Data was analyzed through frequency, percentage and Chi-square test. Based on the results of the study, 45 mothers used public health care facilities (31.82%). Majority of the respondents were high school graduates with 1-2 children. More than half of the mothers included in the study where Philhealth non-members. The study concluded that the risk ratio or relative risk was 0.5 with p-value of 0.0001372071 (0.3389, 0.7378) indicating an association between the level of knowledge regarding essential intrapartum and newborn care and postnatal utilization of health care facilities. All of the respondents used health care facilities. All of the respondents used health care facilities for newborn care; they differed on whether they seek health care from public or private health care facilities. Adequate knowledge was deemed protective; mothers with adequate knowledge were more likely to utilize health care facilities postpartum than those with inadequate knowledge