The Evolution of Post-Starburst Galaxies from z∼1z\sim1 to the Present

Post-starburst galaxies are in the transitional stage between blue, star-forming galaxies and red, quiescent galaxies, and therefore hold important clues for our understanding of galaxy evolution. In this paper, we systematically searched for and identified a large sample of post-starburst galaxies from the spectroscopic dataset of the Sloan Digital Sky Survey (SDSS) Data Release 9. In total, we found more than 6000 objects with redshifts between $z\sim0.05$ and $z\sim1.3$, making this the largest sample of post-starburst galaxies in the literature. We calculated the luminosity function of the post-starburst galaxies using two uniformly selected subsamples: the SDSS Main Galaxy Sample and the Baryon Oscillation Spectroscopic Survey CMASS Sample. The luminosity functions are reasonably fit by half-Gaussian functions. The peak magnitudes shift as a function of redshift from $M\sim-23.5$ at $z\sim0.8$ to $M\sim-20.3$ at $z\sim0.1$. This is consistent with the downsizing trend, whereby more massive galaxies form earlier than low-mass galaxies. We compared the mass of the post-starburst stellar population found in our sample to the decline of the global star-formation rate and found that only a small amount ($\sim1\%$) of all star-formation quenching in the redshift range $z=0.2-0.7$ results in post-starburst galaxies in the luminosity range our sample is sensitive to. Therefore, luminous post-starburst galaxies are not the place where most of the decline in star-formation rate of the universe is happening.Comment: 26 pages, 24 figures, 8 tables. Accepted for publication in The Astrophysical Journa

Identification of a WNT5A-Responsive Degradation Domain in the Kinesin Superfamily Protein KIF26B.

Noncanonical WNT pathways function independently of the β-catenin transcriptional co-activator to regulate diverse morphogenetic and pathogenic processes. Recent studies showed that noncanonical WNTs, such as WNT5A, can signal the degradation of several downstream effectors, thereby modulating these effectors' cellular activities. The protein domain(s) that mediates the WNT5A-dependent degradation response, however, has not been identified. By coupling protein mutagenesis experiments with a flow cytometry-based degradation reporter assay, we have defined a protein domain in the kinesin superfamily protein KIF26B that is essential for WNT5A-dependent degradation. We found that a human disease-causing KIF26B mutation located at a conserved amino acid within this domain compromises the ability of WNT5A to induce KIF26B degradation. Using pharmacological perturbation, we further uncovered a role of glycogen synthase kinase 3 (GSK3) in WNT5A regulation of KIF26B degradation. Lastly, based on the identification of the WNT5A-responsive domain, we developed a new reporter system that allows for efficient profiling of WNT5A-KIF26B signaling activity in both somatic and stem cells. In conclusion, our study identifies a new protein domain that mediates WNT5A-dependent degradation of KIF26B and provides a new tool for functional characterization of noncanonical WNT5A signaling in cells

The Sloan Digital Sky Survey Reverberation Mapping Project: Post-Starburst Signatures in Quasar Host Galaxies at z < 1

Quasar host galaxies are key for understanding the relation between galaxies and the supermassive black holes (SMBHs) at their centers. We present a study of 191 broad-line quasars and their host galaxies at z < 1, using high signal-to-noise ratio (SNR) spectra produced by the Sloan Digital Sky Survey Reverberation Mapping project. Clear detection of stellar absorption lines allows a reliable decomposition of the observed spectra into nuclear and host components, using spectral models of quasar and stellar radiations as well as emission lines from the interstellar medium. We estimate age, mass (M*), and velocity dispersion (sigma*) of the host stars, the star formation rate (SFR), quasar luminosity, and SMBH mass (Mbh), for each object. The quasars are preferentially hosted by massive galaxies with M* ~ 10^{11} Msun characterized by stellar ages around a billion years, which coincides with the transition phase of normal galaxies from the blue cloud to the red sequence. The host galaxies have relatively low SFRs and fall below the main sequence of star-forming galaxies at similar redshifts. These facts suggest that the hosts have experienced an episode of major star formation sometime in the past billion years, which was subsequently quenched or suppressed. The derived Mbh - sigma* and Mbh - M* relations agree with our past measurements and are consistent with no evolution from the local Universe. The present analysis demonstrates that reliable measurements of stellar properties of quasar host galaxies are possible with high-SNR fiber spectra, which will be acquired in large numbers with future powerful instruments such as the Subaru Prime Focus Spectrograph.Comment: ApJ in pres

Deep Photometry in a Remote M31 Major Axis Field Near G1

We present photometry from Hubble Space Telescope (HST)/Wide Field Planetary Camera 2 parallel imagery of a remote M31 field at a projected distance of about 34 kpc from the nucleus near the SW major axis. This field is near the globular cluster G1, and near one of the candidate tidal plumes identified by Ferguson et al. (2002). The F606W (V) and F814W (I) images were obtained in parallel with Space Telescope Imaging Spectrograph spectroscopy of G1 (GO-9099) and total 7.11 hours of integration time -- the deepest HST field in the outer disk of M31 to date, reaching to V ~ 28. The color-magnitude diagram of the field shows a clearly-defined red clump at V = 25.25 and a red giant branch consistent with [Fe/H] ~ -0.7. The lack of a blue horizontal branch contrasts with other M31 halo fields, the Andromeda dwarf spheroidals, and with the nearby globular cluster G1. Comparing the observed luminosity function to the Padova models, we find that at least some of the stellar population must be younger than 6 - 8 Gyr. The outermost detected neutral hydrogen gas disk of M31 lies only 2 kpc in projection from our field. The finding that some giants in the field have radial velocities close to that of the neutral hydrogen gas (Reitzel, Guhathakurta, & Rich 2003) leads us to conclude that our field samples the old, low-surface-brightness disk rather than the true Population II spheroid.Comment: 15 pages, 3 figures. accepted for publication in the A

Mother-child histocompatibility and risk of rheumatoid arthritis and systemic lupus erythematosus among mothers.

The study objective was to test the hypothesis that having histocompatible children increases the risk of rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE), possibly by contributing to the persistence of fetal cells acquired during pregnancy. We conducted a case control study using data from the UC San Francisco Mother Child Immunogenetic Study and studies at the Inova Translational Medicine Institute. We imputed human leukocyte antigen (HLA) alleles and minor histocompatibility antigens (mHags). We created a variable of exposure to histocompatible children. We estimated an average sequence similarity matching (SSM) score for each mother based on discordant mother-child alleles as a measure of histocompatibility. We used logistic regression models to estimate odds ratios (ORs) and 95% confidence intervals. A total of 138 RA, 117 SLE, and 913 control mothers were analyzed. Increased risk of RA was associated with having any child compatible at HLA-B (OR 1.9; 1.2-3.1), DPB1 (OR 1.8; 1.2-2.6) or DQB1 (OR 1.8; 1.2-2.7). Compatibility at mHag ZAPHIR was associated with reduced risk of SLE among mothers carrying the HLA-restriction allele B*07:02 (n = 262; OR 0.4; 0.2-0.8). Our findings support the hypothesis that mother-child histocompatibility is associated with risk of RA and SLE

Double-Peaked Broad Emission Lines in NGC 4450 and Other LINERs

Spectra taken with HST reveal that NGC 4450 emits Balmer emission lines with displaced double peaks and extremely high-velocity wings. This characteristic line profile, previously seen in a few nearby LINERs and in a small fraction of broad-line radio galaxies, can be interpreted as a kinematic signature of a relativistic accretion disk. We can reproduce the observed profile with a model for a disk with a radial range of 1000-2000 gravitational radii and inclined by 27 degrees along the line of sight. The small-aperture HST data also allow us to detect, for the first time, the featureless continuum at optical wavelengths in NGC 4450; the nonstellar nucleus is intrinsically very faint, with M_B = -11.2 mag for D = 16.8 Mpc. We have examined the multiwavelength properties of NGC 4450 collectively with those of other low-luminosity active nuclei which possess double-peaked broad lines and find a number of common features. These objects are all classified spectroscopically as "type 1" LINERs or closely related objects. The nuclear luminosities are low, both in absolute terms and relative to the Eddington rates. All of them have compact radio cores, whose strength relative to the optical nuclear emission places them in the league of radio-loud active nuclei. The broad-band spectral energy distributions of these sources are most notable for their deficit of ultraviolet emission compared to those observed in luminous Seyfert 1 nuclei and quasars. The double-peaked broad-line radio galaxies Arp 102B and Pictor A have very similar attributes. We discuss how these characteristics can be understood in the context of advection-dominated accretion onto massive black holes.Comment: To appear in The Astrophysical Journal. Latex, 15 pages, embedded figures and tabl

Conformal Anomalies in Noncommutative Gauge Theories

We calculate conformal anomalies in noncommutative gauge theories by using the path integral method (Fujikawa's method). Along with the axial anomalies and chiral gauge anomalies, conformal anomalies take the form of the straightforward Moyal deformation in the corresponding conformal anomalies in ordinary gauge theories. However, the Moyal star product leads to the difference in the coefficient of the conformal anomalies between noncommutative gauge theories and ordinary gauge theories. The $\beta$ (Callan-Symanzik) functions which are evaluated from the coefficient of the conformal anomalies coincide with the result of perturbative analysis.Comment: 17 pages, Latex, no figures, minor corrections and references added; to appear in Phys. Rev.