Avaliação da tecnologia zoneamento de risco climático da cultura do sorgo no Estado de Pernambuco.

O zoneamento da área de risco climático do sorgo no Estado de Pernambuco veio atender a uma demanda do setor avícola que estava crescendo mas seus custos eram altos pela dependência do milho para a produção da ração das aves. O milho é muito sensível à estiagem enquanto o sorgo é cultivado em áreas muito secas e/ou muito quentes próprias da região do Semi-árido e Sertão, onde a produtividade de outros cereais é antieconômica. Este trabalho fez uma avaliação dos impactos da tecnologia do zoneamento do risco climático da cultura do sorgo nas áreas do semi-árido de Pernambuco, sob os aspectos econômicos, sociais e ambientais. O estudo abrangeu um período de três anos, empregando a Metodologia de Referência da Embrapa. Sob o ponto de vista econômico, o resultado encontrado foi de um grande aumento da área plantada, da quantidade produzida de sorgo e da renda gerada. No aspecto social houve aumento de emprego. Quanto ao aspecto ambiental não houve preocupação na conservação e recuperação dos recursos naturais.bitstream/CNPS-2010/14746/1/bpd139-2009-avaliacao-zoneamento-sorgo.pd

BMQ

BMQ: Boston Medical Quarterly was published from 1950-1966 by the Boston University School of Medicine and the Massachusetts Memorial Hospitals

Motion Sickness Lessons from the Southern Ocean

BACKGROUND: The objectives were to assess the prevalence, severity, and medication taken, and to look for predictive factors, in order to better identify characteristics of passengers at risk of motion sickness during transport from Hobart in Tasmania to the French polar stations in Antarctica. METHODS: There were 239 passengers who were surveyed over 4 yr with 4 round trips per year using the Motion Sickness Susceptibility Questionnaire (MSSQ), Simulator Sickness Questionnaire (SSQ), state-trait anxiety test (STAI -Trait and STAI -State), and general parameters (age, gender, number of trips, jet-lag, direction of the trip), medication, calculation of the distance of each passenger’s cabin to the Centre of Gravity (CoG.). RESULTS: While the passengers had a low intrinsic sensitivity to motion sickness (MSSQ), 94% reported at least one SSQ symptom of motion sickness, and 38% vomited. Five associated factors were discovered: greater initial sensitivity (MSSQ), anticipation of being ill, younger age, higher level of anxiety at midtrip, and greater distance from the CoG. Of the passengers, there were 54% who took anti-motion sickness medication at different times of the trip, however, these passengers experienced more nausea. This could be due to self-selection since they were more sensitive to motion sickness. CONCLUSION: We identified three predictive factors of motion sickness (greater intrinsic susceptibility, younger age, and greater cabin distance from the CoG). For preventive purposes, two associated factors of MS (anticipation of being ill, MSSQ score) were determined to classify three groups of risk of MS to improve passenger care during the trip

Increased aortic stiffness and blood pressure in non-classic Pompe disease

Vascular abnormalities and glycogen accumulation in vascular smooth muscle fibres have been described in Pompe disease. Using carotid-femoral pulse wave velocity (cfPWV), the gold standard methodology for determining aortic stiffness, we studied whether aortic stiffness is increased in patients with Pompe disease. Eighty-four adult Pompe patients and 179 age- and gender-matched volunteers participated in this cross-sectional case-controlled study. Intima media thickness and the distensibility of the right common carotid artery were measured using a Duplex scanner. Aortic augmentation index, central pulse pressure, aortic reflexion time and cfPWV were assessed using the SphygmoCor® system. CfPWV was higher in patients than in volunteers (8.8 versus 7.4 m/s, p < 0.001). This difference was still present after adjustment for age, gender, mean arterial blood pressure (MAP), heart rate and diabetes mellitus (p = 0.001), and was shown by subgroup analysis to apply to the 40-59 years age group (p = 0.004) and 60+ years age group (p = 0.01), but not to younger age groups (p = 0.99). Except for a shorter aortic reflexion time (p = 0.02), indirect indicators of arterial stiffness did not differ between patients and volunteers. Relative to volunteers (20 %), more Pompe patients had a history of hypertension (36 %, p = 0.005), and the MAP was higher than in volunteers (100 versus 92 mmHg, p < 0.001). This study shows that patients with non-classic Pompe disease have increased aortic stiffness and blood pressure. Whether this is due to glycogen accumulation requires further investigation. To reduce the potential risk of cardiovascular diseases, we recommend that blood pressure and other common cardiovascular risk factors are monitored regularly

Five areas to advance branding theory and practice

The paper suggests five areas to advance branding theory and practice based on the authors’ recent work in brand management. In this commentary, we aim to put forward suggestions and ideas for further research in brand management; ideas, which we believe will have an impact on the way branding is researched and practiced by both academics and practitioners alike. We will focus on the future of branding in the following areas, inspired by our own work in the field: (1) branding in higher education, (2) branding in Asia Pacific, (3) brand ambidexterity, (4) brand innovation on social media, and (5) brand likeability

Pga26 mediates filamentation and biofilm formation and is required for virulence in Candida albicans.

© 2011 Federation of European Microbiological Societies. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ This document is the Published version of a Published Work that appeared in final form in FEMS Yeast Research. To access the final edited and published work see https://doi.org/10.1111/j.1567-1364.2011.00727.xThe Candida albicans gene PGA26 encodes a small cell wall protein and is upregulated during de novo wall synthesis in protoplasts. Disruption of PGA26 caused hypersensitivity to cell wall-perturbing compounds (Calcofluor white and Congo red) and to zymolyase, which degrades the cell wall β-1,3-glucan network. However, susceptibility to caspofungin, an inhibitor of β-1,3-glucan synthesis, was decreased. In addition, pga26Δ mutants show increased susceptibility to antifungals (fluconazol, posaconazol or amphotericin B) that target the plasma membrane and have altered sensitivities to environmental (heat, osmotic and oxidative) stresses. Except for a threefold increase in β-1,6-glucan and a slightly widened outer mannoprotein layer, the cell wall composition and structure was largely unaltered. Therefore, Pga26 is important for proper cell wall integrity, but does not seem to be directly involved in the synthesis of cell wall components. Deletion of PGA26 further leads to hyperfilamentation, increased biofilm formation and reduced virulence in a mouse model of disseminated candidiasis. We propose that deletion of PGA26 may cause an imbalance in the morphological switching ability of Candida, leading to attenuated dissemination and infection

Determinants of the Digital Orientation of Small Businesses

A company oriented toward digitalization recognizes digital resources throughout the company and integrates them with value creation. Digital orientation, formed by a combination of market orientation, entrepreneurial orientation, relationship orientation, and technology orientation, is thus considered as a top strategic priority for companies to stay competitive. Prior studies call for further evidence on what determines the digital orientation of small businesses. We study the conditions under which small companies are likely to pursue different digital orientations, and which types of companies are most probably involved in embracing different digital orientations. The results show that the companies that have digitality well represented in their strategy embrace digital orientation more than the companies that do not have digitality well represented in their strategy. Also, companies’ willingness to grow affects the level of digital orientation, whereas competitive intensity in markets does not.Post-print / Final draf