We Thought We Knew the Landscape of Literacy Teacher Education: Ten Surprises From Our Research

Vol. 6. No. 2 Nov 2016 In this month's edition of RiTE we are fortunate to have not one but three! Clare Kosnik is Director of the Dr. Eric Jackman Institute of Child Study at the Ontario Institute for Studies in Education, University of Toronto (OISE/UT). Her area of research is teacher education which she has systematically studied. She is now conducting a large-scale study of 28 literacy/English teacher educators in four countries. Lydia Menna is an Assistant Professor of Language and Literacy in the Department of Elementary Education at the University of Alberta. Her research interests are in the areas of teacher education, multiliteracies, critical literacy, and teacher identity construction. She completed her doctorate in the Department of Curriculum, Teaching, and Learning at the Ontario Institute for Studies in Education, University of Toronto. Pooja Dharamshi is an Assistant Professor of Teacher Education in the Faculty of Education at Simon Fraser University. Her research interests are in the areas of critical literacy and teacher education. She recently completed her doctoral studies at the Ontario Institute for Studies in Education/ University of Toronto in the department of Curriculum, Teaching, and Learning. Her study explored the practices and pedagogies of literacy teacher educators with a critical stance

Importance of basophil activation testing in insect venom allergy

<p>Abstract</p> <p>Background</p> <p>Venom immunotherapy (VIT) is the only effective treatment for prevention of serious allergic reactions to bee and wasp stings in sensitized individuals. However, there are still many questions and controversies regarding immunotherapy, like selection of the appropriate allergen, safety and long term efficacy.</p> <p>Methods</p> <p>Literature review was performed to address the role of basophil activation test (BAT) in diagnosis of venom allergy.</p> <p>Results</p> <p>In patients with positive skin tests or specific IgE to both honeybee and wasp venom, IgE inhibition test can identify sensitizing allergen only in around 15% and basophil activation test increases the identification rate to around one third of double positive patients. BAT is also diagnostic in majority of patients with systemic reactions after insect stings and no detectable IgE. High basophil sensitivity to allergen is associated with a risk of side effects during VIT. Persistence of high basophil sensitivity also predicts a treatment failure of VIT.</p> <p>Conclusion</p> <p>BAT is a useful tool for better selection of allergen for immunotherapy, for identification of patients prone to side effects and patients who might be treatment failures. However, long term studies are needed to evaluate the accuracy of the test.</p

Implications from clean observables for the binned analysis of B -> K*ll at large recoil

We perform a frequentist analysis of q^2-dependent B-> K*(->Kpi)ll angular observables at large recoil, aiming at bridging the gap between current theoretical analyses and the actual experimental measurements. We focus on the most appropriate set of observables to measure and on the role of the q^2-binning. We highlight the importance of the observables P_i exhibiting a limited sensitivity to soft form factors for the search for New Physics contributions. We compute predictions for these binned observables in the Standard Model, and we compare them with their experimental determination extracted from recent LHCb data. Analyzing b->s and b->sll transitions within four different New Physics scenarios, we identify several New Physics benchmark points which can be discriminated through the measurement of P_i observables with a fine q^2-binning. We emphasise the importance (and risks) of using observables with (un)suppressed dependence on soft form factors for the search of New Physics, which we illustrate by the different size of hadronic uncertainties attached to two related observables (P_1 and S_3). We illustrate how the q^2-dependent angular observables measured in several bins can help to unravel New Physics contributions to B-> K*(->Kpi)ll, and show the extraordinary constraining power that the clean observables will have in the near future. We provide semi-numerical expressions for these observables as functions of the relevant Wilson coefficients at the low scale.Comment: 50 pages, 21 figures. Improved form factor analysis, conclusions unchanged. Plots with full resolution. Version published in JHE

Sustainable Publishing for Digital Scholarship in the Humanities

This is a link to a webinar recording of a Charleston Conference webinar titled Sustainable Publishing for Digital Scholarship in the Humanities, sponsored by University of Michigan Press and hosted by the Charleston Conference. It was originally broadcast on the internet on October 2, 2019. ==== From the Charleston Conference website: Session Description: Scholarly authors are increasingly using digital tools. They want to produce enhanced ebooks and interactive scholarly works, but these tend not to fit into existing publisher and librarian workflows. Fulcrum is a platform developed at the University of Michigan which supports authors who want to push the boundaries of the book. The University of Michigan Press Ebook Collection (UMP EBC) includes an increasing number of enhanced titles and takes full advantage of the rich features on the Fulcrum platform. Thanks to the support of purchasing libraries, UMP EBC is able to sustain the publication of new forms of scholarship, including open access titles, and sustain the open source, community-based scholarly infrastructure. In this webinar attendees will learn about this new form of scholarship, including how it is being sustained by the community via UMP EBC and Fulcrum, and walk away inspired to sustain this burgeoning community. Presenters: Lanell White, Director of Sales, Marketing, and Outreach (Michigan Publishing) Sara Cohen, Editor for American Studies, University of Michigan Press Andrée J. Rathemacher, Head, Acquisitions, University of Rhode Island (Librarian) Professor Anne Ruggles Gere, editor of Developing Writers in Higher Education: A Longitudinal Study Professors Abigail De Kosnik and Keith P. Feldman, Editors, #identity: Hashtagging Race, Gender, Sexuality, and Nation Doctoral Candidate and Rackham Public Engagement Fellow, Matthew Naglak, Researcher, A Mid-Republican House From Gabii ==== Included as supplemental files are: PDF printout of Charleston Conference website page advertising the webinar PDF printout of a 9/26/2019 email to the Charleston Library Conference mailing list advertising the webinar PDF printout of a 9/26/2019 email to the LYROFFERS mailing list advertising the webinar Andrée Rathemacher\u27s webinar speaking notes in PDF format Included as supplemental files (suppressed from public view) are: Webinar video recording in MP4 format Webinar video recording in WMV format Slides for webinar presentation in PDF format Slides with notes for webinar presentation in PDF format Results of attendee polls taken during webinar in PDF format Andrée Rathemacher\u27s webinar planning notes in PDF format Approximately 75 people attended the webinar; approximately 150 registered and received a link to the recording

Integrative transcriptomic analysis in human and mouse model of anaphylaxis identifies gene signatures associated with cell movement, migration and neuroinflammatory signalling

Background: Anaphylaxis is an acute life-threatening allergic reaction and a concern at a global level; therefore, further progress in understanding the underlying mechanisms and more effective strategies for diagnosis, prevention and management are needed. Objective: We sought to identify the global architecture of blood transcriptomic features of anaphylaxis by integrating expression data from human patients and mouse model of anaphylaxis. Methods: Bulk RNA-sequencings of peripheral whole blood were performed in: i) 14 emergency department (ED) patients with acute anaphylaxis, predominantly to Hymenoptera venom, ii) 11 patients with peanut allergy undergoing double-blind, placebo-controlled food challenge (DBPCFC) to peanut, iii) murine model of IgE-mediated anaphylaxis. Integrative characterisation of differential gene expression, immune cell-type-specific gene expression profiles, and functional and pathway analysis was undertaken. Results: 1023 genes were commonly and significantly dysregulated during anaphylaxis in ED and DBPCFC patients; of those genes, 29 were also dysregulated in the mouse model. Cell-type-specific gene expression profiles showed a rapid downregulation of blood basophil and upregulation of neutrophil signature in ED and DBPCFC patients and the mouse model, but no consistent and/or significant differences were found for other blood cells. Functional and pathway analysis demonstrated that human and mouse blood transcriptomic signatures of anaphylaxis follow trajectories of upregulation of cell movement, migration and neuroinflammatory signalling, and downregulation of lipid activating nuclear receptors signalling. Conclusion: Our study highlights the matched and extensive blood transcriptomic changes and suggests the involvement of discrete cellular components and upregulation of migration and neuroinflammatory pathways during anaphylaxis

Effectiveness of classroom based crew resource management training in the intensive care unit: study design of a controlled trial

<p>Abstract</p> <p>Background</p> <p>Crew resource management (CRM) has the potential to enhance patient safety in intensive care units (ICU) by improving the use of non-technical skills. However, CRM evaluation studies in health care are inconclusive with regard to the effect of this training on behaviour and organizational outcomes, due to weak study designs and the scarce use of direct observations. Therefore, the aim of this study is to determine the effectiveness and cost-effectiveness of CRM training on attitude, behaviour and organization after one year, using a multi-method approach and matched control units. The purpose of the present article is to describe the study protocol and the underlying choices of this evaluation study of CRM in the ICU in detail.</p> <p>Methods/Design</p> <p>Six ICUs participated in a paired controlled trial, with one pre-test and two post test measurements (respectively three months and one year after the training). Three ICUs were trained and compared to matched control ICUs. The 2-day classroom-based training was delivered to multidisciplinary groups. Typical CRM topics on the individual, team and organizational level were discussed, such as situational awareness, leadership and communication. All levels of Kirkpatrick's evaluation framework (reaction, learning, behaviour and organisation) were assessed using questionnaires, direct observations, interviews and routine ICU administration data.</p> <p>Discussion</p> <p>It is expected that the CRM training acts as a generic intervention that stimulates specific interventions. Besides effectiveness and cost-effectiveness, the assessment of the barriers and facilitators will provide insight in the implementation process of CRM.</p> <p>Trial registration</p> <p>Netherlands Trial Register (NTR): <a href="http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=1976">NTR1976</a></p

Governing Boards and Profound Organizational Change in Hospitals

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/69047/2/10.1177_107755878904600204.pd