93 research outputs found
Imaging Changes in Very Young Children with Brain Tumors Treated with Proton Therapy and Chemotherapy
ABSTRACT SUMMARY: PT promises to reduce side effects in children with brain tumors by sparing normal tissue compared with 3D conformal or intensity-modulated radiation therapy. Information is lacking about the combined effects of PT and chemotherapy in young children. We describe imaging changes in 8 very young children with localized brain tumors who received PT after chemotherapy. Mostly transient signal abnormalities and enhancement in brain parenchyma were observed by serial MR imaging, which were consistent with radiation-induced effects on normal-appearing tissue. Correlation with PT planning data revealed that the areas of imaging abnormality were located within or adjacent to the volume that received the highest radiation dose. Radiologists should be aware of these findings in children who receive PT after chemotherapy. In this report, we describe the time course of these PT-related imaging findings and correlate them with treatment and clinical outcomes. ABBREVIATIONS: AT/RT Ď atypical teratoid rhabdoid tumor; CGE Ď cobalt gray equivalent; CPC Ď choroid plexus carcinoma; PNET Ď primitive neuroectoderma
The stability of osseous metastases of the spine in lung cancer – a retrospective analysis of 338 cases
Resistance training concomitant to radiotherapy of spinal bone metastases – survival and prognostic factors of a randomized trial
Metástases do segmento torácico e lombar da coluna vertebral: estudo prospectivo comparativo entre o tratamento cirúrgico e radioterápico com a imobilização externa e radioterapia
Stereotactic linac radiosurgery and hypofractionated stereotactic radiotherapy for pediatric arteriovenous malformations of the brain: experiences of a single institution
The effect of excision of the posterior arch of C1 on C1/C2 fusion using transarticular screws
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