Toksisitas Sub-kronik Buah Pare (Momordica Charantia L.) Pada Tikus Putih

The fruits of Momordica charantia L. (pare) are widely used as a traditional medicine for oxyuriasis, fever, cough and diabetes. The subchronic toxicity test was carried out on the aquaous extract of the fruits of Momordica charantia L. The test was done on 72 female rats of LMR strain for 3 months with a method developed by the Pharmaceutical Research and Development Centre of the National Institute of Health Research and Development, Jakarta. The rat organs examined were heart, lung, liver, kidney, stomach, muscle, pancreas, intestine and spleen. The results showed that there are no negative effects on the rat organs examined at a dose up to 200 mg/100 g body weight administered orally for 3 months