733 research outputs found
An exploratory study of Master's degree programs in public health nursing in thirteen schools in the United States of America
Thesis (M.S.)--Boston Universit
Differential Effect of Atpenin A5 on ROS Production from Wild- Type Mitochondrial Complex II in Human Cancer Cells and Normal Cells
Human mitochondrial complex II is an intriguing enzyme, which has been the focus of medical research during the past few decades since it contributes to pathogenesis of mitochondrial diseases as well as a target for chemotherapy. Reactive oxygen species (ROS) produced by this enzyme has been implicated in both these conditions. While ROS produced from mutated mitochondrial complex II has been implicated in pathogenesis of mitochondrial diseases, ROS produced from pharmacologically inhibited mitochondrial complex II has been implicated in cancer cell death. In this chapter, we show that inhibition of mitochondrial complex II in human cancer cells with atpenin A5 produces detectable levels of ROS while normal cells do not. Thus, this enzyme may be used as a potential target for developing new anticancer drugs to trigger ROS-mediated selective death of cancer cells
Biochemical Constituents of Shrimps from Semi-Intensive and Modified-Extensive Culture Ponds
A quantitative study on the occurrence of major biochemical constituents including
protein, carbohydrate, lipid and cholesterol in the muscle of different growth stages of
Penaeus monodon collected from semi-intensive (SI) and modified-extensive (ME) culture
ponds of coastal Andhra Pradesh, adopting different feeding schedules was undertaken.
The objective was to determine the effects of the age of shrimp and the stocking density
on the biochemical composition of the muscle. Protein was found to be the major biochemical
constituent and an increase in protein content with advancement of shrimp age was
recorded. Glycogen occurred only in traces. Lipid and cholesterol occurred in moderate
quantities with concentrations slightly higher in shrimps of SI ponds as compared to those
of ME ponds. Overall, the stocking density had little impact on protein and glycogen concentration
in the muscle
Characterization of Vibrio spp. associated with Diseased Shrimp from Culture Ponds of Andhra Pradesh(India)
Surveys undertaken on diseases caused by Vibrio spp. in Penaeus monodon from culture ponds of coastal Andhra Pradesh recorded the occurrence of five types of diseases : tailnecrosis,shelldisease,reddisease,looseshellsyndrome(LSS), and white gut disease(WGD). Amongthese,LSS,WGD,and red disease caused mass mortalities in shrimp cultureponds. Six species of Vibrio V.harveyi,V.parahaemolyticus,V.alginolyticus,V.anguillarum,V.vulnificus,and V.splendidus are associated with the diseased shrimp. The number of Vibrio spp. associated with each disease ranged from two to five. Additionally,shrimp with red disease had concurrent infections with white spot syndrome virus.Vibrio harveyi in the case of LSS and WGD, V. parahaemolyticus for reddisease, and V.algino-lyticus for shell disease are the major etiologcalagents. Differences occur in the degree of virulence of different species of Vibrio and also different isolates of the same species. Vibrioharveyi isolated from LSS shrimp is the most virulent.Ingeneral, allthe Vibrio isolates from LSS shrimp tend to be more virulent as compared to their counter parts fromo the diseased shrimp.It is apparent that the degree of virulence of various Vibrio isolates depends on its source and the pond environmental conditions. Most of the Vibrio isolates showed susceptibility to oxy-tetracycline, norfloxacin, and ciprofloxacin. The luminous V.harveyi exhibited resistance to many antibiotics and susceptibility to only three drugs. Considering the emergence of antimicrobial resistant strains of Vibrio, the need for using probiotics in place of antibiotics for disease control is stressed
Characteristics, Pathogenicity and Antibiotic Sensitivity of Bacterial Isolates from White Spot Diseased Shrimp
A bacteriological study was undertaken on white spot diseased shrimp collected from
extensive, modified-extensive and semi-intensive ponds located at Visakhapatnam and East
Godavari districts of North Coastal Andhra Pradesh. The diseased shrimp exhibited white
spots and red discoloration of the body. Four species of bacteria, V. alginolyticus, V.
parahaemolyticus, V. anguillarum and Pseudomonas aeruginosa were isolated from the
hemolymph of the diseased shrimp. V. alginolyticus was found to be the most dominant
and virulent species. All the bacterial isolates showed sensitivity towards oxytetracycline
which is a commonly used antibiotic in culture ponds
Survival, Growth and Production of Penaeus monodon in Modified- Extensive and Semi Intensive Culture Systems of Andhra Pradesh, India
An analysis was made on the stocking density, survival, growth and production of Penaeus monodon
in semi intensive (SI) and modified extensive (ME) shrimp culture ponds located in East Godavari district of
Coastal Andhra Pradesh, India. Survival of shrimp in the ME systems with low stocking densities is higher (56 -
88%) than in the SI systems (12.3 тАУ 52%) with higher stocking densities. Growth of shrimp is dependent not only
on the stocking density but also on the management practices. Although the percent survival is more in ME system
the growth is much faster in SI system owing to better management practices. Weight gain of shrimp was more
rapid in the SI system than in the ME system initially up to 90 days of culture (DOC) but the trend was reverse in the
later age of culture period. The optimum stocking density for achieving maximum production in the area is
suggested as 10-15 individuals / m2 in SI ponds and 3-5 individuals / m2 in ME ponds
Development of Image Based Model for Basic Standing Yoga Poses that Control Type-2 Diabetes
Yoga is one of the ancient practices originated in India that helps in balancing mind and body of human. For the past few decades it has got wide spread throughout the world. Many are practicing it in the presence of yoga tutor or following some online modes. But improper practice may cause major harm to muscles and ligaments of the human body. There are different asanas proposed in the Patanjali Yoga Sutra that can cure different diseases. This paper, proposes a mathematical model for a set of yoga asanas that can help cure Type -2 Diabetes. A noninvasive analysis has been implemented using Kinect Sensor and LabVIEW software to analyze the performance of the practitioner. The joints are subjected to the flexibility of the practitioner without any overstress
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