The relationship between the helicobacter pylori seropositivity with systemic and local oxidative status and hyperemesis gravidarum: a pilot study

Akpak, Yasam Kemal/0000-0002-1699-8667WOS: 000427919300017PubMed: 28347201Objectives: The aim of study was to determine the helicobacter pylori (HP) seropositivity and oxidative parameters in serum and saliva of pregnant women with poor oral hygiene and hyperemesis gravidarum (HG).Methods: A case-control study was conducted involving 50 pregnant women in their first trimester of pregnancy. Twenty-five subjects had a diagnosis of HG, and remaining 25 were healthy pregnant women who served as control subjects were included. The groups were adjusted for age, parity and gestational week. All patients were subjected to the measurement of total oxidant status (TOS) and total antioxidant status in serum and saliva. Also HP seropositivity was investigated.Results: Serum TAS and TOS values were similar, although oxidative burden in saliva of women with HG were significantly higher than controls. HP seropositivity was found to be 24% in women with HG and 4% of controls.Conclusions: Our results suggest that significantly increased oxidative burden and slightly decreased antioxidative capacity of saliva may be involved in the pathogenesis of HG and this condition may be the result of HP infection which was found to be significantly more common in women with poor oral hygiene and HG

Effect of Gum Chewing and Coffee Consumption on Intestinal Motility in Caesarean Sections

Akpak, Yasam Kemal/0000-0002-1699-8667WOS: 000423935700012Aim: The time to first postoperative flatulence and defaecation are two of the main factors that determine caesarean patient comfort and morbidity. In this study, the effect of postoperative gum chewing and decaffeinated coffee consumption on intestinal motility was tested in full-term caesarean sections without complication with a prospective, randomised controlled trial. Material and Method: 100 women who underwent caesarean section without a complication were divided into 4 groups using the simple randomisation method: Group 1 (women given sugar-free gum at 4-hour intervals after postoperative hour 2 until defaecation) n:25; Group 2 (women given 100 mL coffee at 4-hour intervals beginning from postoperative hour 2 until defaecation for three times a day) n:25; Group 3 (Sham group-women given 100 ml hot water at 4-hour intervals beginning from postoperative hour 2 until defaecation for three times a day) n:25; and Group 4 (control group) n:25. Time to sensation of first bowel movement and time to passage of first flatus and defaecation were compared between the groups. Results: Times to sensation of first bowel movement and passage of first flatus were significantly shorter in Group 1 compared to the sham and control groups. Time to first defaecation was also detected to be significantly shorter in Groups 1, 2, and 3 compared to the control group. No significant difference could be detected between the groups. Discussion: Sugar-free gum chewing and decaffeinated coffee consumption during postoperative period after caesarean section may decrease the time to first flatulence and defaecation and thus, the hospitalisation time

Effect of vaginal cleansing on postoperative factors in elective caesarean sections: a prospective, randomised controlled trial

Akpak, Yasam Kemal/0000-0002-1699-8667; Ozdamar, Ozkan/0000-0001-9730-0285WOS: 000389666700014PubMed: 27049354Objective: To assess the effect of povidone iodine versus benzalkonium chloride, which were applied preoperatively for vaginal disinfection in caesarean sections, on postoperative factors. Methods: One hundred and twenty patients underwent elective caesarean section were divided into three groups using the simple randomisation method: Group 1 (povidone iodine, n: 41); Group 2 (benzalkonium chloride, n: 39); Group 3 (control group, n: 40). Demographic data, duration of operation, amount of bleeding, postoperative pain, time to first flatulence and defaecation, haematological parameters on postoperative day 1 were compared between three groups. Pain evaluation was performed at 6th and 24th postoperative hour using Visual Analogue Scale. Results: No statistically significant differences were detected between the groups in demographic characteristics. There were no significant differences between the groups with respect to the duration of operation and hospital stay. The patients in the group who underwent povidone iodine vaginal cleansing had statistically significantly less postoperative pain as compared to control group. No difference was observed between the groups in haematological parameters other than C-reactive protein (CRP); however, CRP levels at 24th post-operative hour were significantly lower in Group 1 compared to the other groups. Conclusions: The preoperative vaginal cleansing with povidone iodine could reduce the postoperative pain, analgesic need and infection parameter