The percent overlap between the significant finding maps using the FWE-DTI <i>f</i>-value.

<p>The percent overlap between the significant finding maps using the FWE-DTI <i>f</i>-value.</p

Seed ROIs and example segmentation of the corpus callosum overlaid on an MNI T1-weighted template.

<p>The CC was segmented into the following five regions: CC-I (yellow), CC-II (red), CC-III (blue), CC-IV (orange), and CC-V (green). The middle image shows a streamline reconstruction of the CC with DEC encoding based on the primary eigenvector direction. The rightmost image shows the same reconstruction with color determined by the seed ROI from which the tract originated.</p

Higher levels of pTau₁₈₁/Aβ42 were associated with higher DTI MD primarily in the left and right temporal lobes.

<p>The color scale, underlay, and presented slices are the same as those in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0173982#pone.0173982.g003" target="_blank">Fig 3</a>.</p

FWE-DTI tractography results.

<p>FWE-DTI tractography results.</p

Linear Pearson Correlation between biomarkers and age.

<p>Linear Pearson Correlation between biomarkers and age.</p

The largest contiguous cluster for which FWE-DTI <i>f</i>-value correlated with pTau₁₈₁/Aβ42.

<p>All other clusters were masked out of the image. The color scale is the same as that of <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0173982#pone.0173982.g003" target="_blank">Fig 3</a>.</p

Diffusion metrics of tracts.

<p>All values are listed as mean ± standard deviation.</p

The total extent of significant voxels (mm³).

<p>The total extent of significant voxels (mm³).</p

Listing of all significant clusters for which the DTI MD was correlated to one of the predictors.

<p>Listing of all significant clusters for which the DTI MD was correlated to one of the predictors.</p

The ROIs used to define the fornix (top row) and superior cingulum (bottom row) in template space.

<p>Fornix tracts were reconstructed if they passed through the columns (green), body (blue) and either the right crux (red) or left crux (yellow). Cingulum tracts were reconstructed if they passed through an anterior ROI (left: yellow, right: purple) and a posterior ROI (left: orange, right: green).</p