Evaluation of Goitrogenic Content of Common Vegetables in South West Nigeria

Endemic goiter and associated iodine deficiency disorders (IDD) are prevalent in south west Nigeria. The present study was undertaken to identify the role of dietary goitrogen in the etiology of endemic goiter. Perchlorate, fluoride, nitrate, bromide, chloride, phosphate and cyanide content of common vegetables viz., cabbage, African Eggplant, Giant pigweed, Scent leaf, Amaranth, Tree Spinach, Black nightshade, consumed by the population of the region were measured. All the dietary goitrogen content in the investigated vegetables were found to be within the Acceptable Daily Intake and this observation suggests that in addition to iodine deficiency dietary intake of a cyanogenic plant, the combination of chemicals may play some role for the persistence of endemic goiter in Southwest Nigeria

The African Stopwords project:curating stopwords for African languages

Stopwords are fundamental in Natural Language Processing (NLP) techniques for information retrieval. One of the common tasks in preprocessing of text data is the removal of stopwords. Currently, while high-resource languages like English benefit from the availability of several stopwords, low-resource languages, such as those found in the African continent, have none that are standardized and available for use in NLP packages. Stopwords in the context of African languages are understudied and can reveal information about the crossover between languages. The \textit{African Stopwords} project aims to study and curate stopwords for African languages. In this paper, we present our current progress on ten African languages as well as future plans for the project

Potential Role of Oxidative Stress in the Production of Volatile Organic Compounds in Obesity

Obesity is associated with numerous health issues such as sleep disorders, asthma, hepatic dysfunction, cancer, renal dysfunction, diabetes, cardiovascular complications, and infertility. Previous research has shown that the distribution of excess body fat, rather than excess body weight, determines obesity-related risk factors. It is widely accepted that abdominal fat is a serious risk factor for illnesses associated with obesity and the accumulation of visceral fat promotes the release of pro-oxidants, pro-inflammatory, and reactive oxygen species (ROS). The metabolic process in the human body produces several volatile organic compounds (VOCs) via urine, saliva, breath, blood, skin secretions, milk, and feces. Several studies have shown that VOCs are released by the interaction of ROS with underlying cellular components leading to increased protein oxidation, lipid peroxidation, or DNA damage. These VOCs released via oxidative stress in obese individuals may serves as a biomarker for obesity-related metabolic alterations and disease. In this review, we focus on the relationship between oxidative stress and VOCs in obesity

Evaluation of Goitrogenic Content of Common Vegetables in South West Nigeria

Endemic goiter and associated iodine deficiency disorders (IDD) are prevalent in south west Nigeria. The present study was undertaken to identify the role of dietary goitrogen in the etiology of endemic goiter. Perchlorate, fluoride, nitrate, bromide, chloride, phosphate and cyanide content of common vegetables viz., cabbage, African Eggplant, Giant pigweed, Scent leaf, Amaranth, Tree Spinach, Black nightshade, consumed by the population of the region were measured. All the dietary goitrogen content in the investigated vegetables were found to be within the Acceptable Daily Intake and this observation suggests that in addition to iodine deficiency dietary intake of a cyanogenic plant, the combination of chemicals may play some role for the persistence of endemic goiter in Southwest Nigeria

MasakhaNER: Named entity recognition for African languages

International audienceWe take a step towards addressing the underrepresentation of the African continent in NLP research by bringing together different stakeholders to create the first large, publicly available, high-quality dataset for named entity recognition (NER) in ten African languages. We detail the characteristics of these languages to help researchers and practitioners better understand the challenges they pose for NER tasks. We analyze our datasets and conduct an extensive empirical evaluation of stateof-the-art methods across both supervised and transfer learning settings. Finally, we release the data, code, and models to inspire future research on African NLP.

Evaluation of prognostic risk models for postoperative pulmonary complications in adult patients undergoing major abdominal surgery: a systematic review and international external validation cohort study

Background Stratifying risk of postoperative pulmonary complications after major abdominal surgery allows clinicians to modify risk through targeted interventions and enhanced monitoring. In this study, we aimed to identify and validate prognostic models against a new consensus definition of postoperative pulmonary complications. Methods We did a systematic review and international external validation cohort study. The systematic review was done in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. We searched MEDLINE and Embase on March 1, 2020, for articles published in English that reported on risk prediction models for postoperative pulmonary complications following abdominal surgery. External validation of existing models was done within a prospective international cohort study of adult patients (≥18 years) undergoing major abdominal surgery. Data were collected between Jan 1, 2019, and April 30, 2019, in the UK, Ireland, and Australia. Discriminative ability and prognostic accuracy summary statistics were compared between models for the 30-day postoperative pulmonary complication rate as defined by the Standardised Endpoints in Perioperative Medicine Core Outcome Measures in Perioperative and Anaesthetic Care (StEP-COMPAC). Model performance was compared using the area under the receiver operating characteristic curve (AUROCC). Findings In total, we identified 2903 records from our literature search; of which, 2514 (86·6%) unique records were screened, 121 (4·8%) of 2514 full texts were assessed for eligibility, and 29 unique prognostic models were identified. Nine (31·0%) of 29 models had score development reported only, 19 (65·5%) had undergone internal validation, and only four (13·8%) had been externally validated. Data to validate six eligible models were collected in the international external validation cohort study. Data from 11 591 patients were available, with an overall postoperative pulmonary complication rate of 7·8% (n=903). None of the six models showed good discrimination (defined as AUROCC ≥0·70) for identifying postoperative pulmonary complications, with the Assess Respiratory Risk in Surgical Patients in Catalonia score showing the best discrimination (AUROCC 0·700 [95% CI 0·683–0·717]). Interpretation In the pre-COVID-19 pandemic data, variability in the risk of pulmonary complications (StEP-COMPAC definition) following major abdominal surgery was poorly described by existing prognostication tools. To improve surgical safety during the COVID-19 pandemic recovery and beyond, novel risk stratification tools are required. Funding British Journal of Surgery Society