Tobacco Mosaic Virus Templated Synthesis of One Dimensional Inorganic–Polymer Hybrid Fibres

Inorganic–polymer hybrid nanofibres were prepared by using a rod-like tobacco mosaic virus (TMV) as a template. With tetraethylorthosilicate (TEOS) as a precursor, long silica-coated TMVfibres were formed via a head-to-tail assembly, which showed a substantial increase of the elastic modulus. Furthermore, homogenous titania–TMV hybrid fibres could be prepared using polyaniline-coated TMV fibres as a template, which were used to form a composite film that was able to sense liquefied petroleum gases

Tobacco Mosaic Virus Templated Synthesis of One Dimensional Inorganic-Polymer Hybrid Fibres

Inorganic–polymer hybrid nanofibres were prepared by using a rod-like tobacco mosaic virus (TMV) as a template. With tetraethylorthosilicate (TEOS) as a precursor, long silica-coated TMVfibres were formed via a head-to-tail assembly, which showed a substantial increase of the elastic modulus. Furthermore, homogenous titania–TMV hybrid fibres could be prepared using polyaniline-coated TMV fibres as a template, which were used to form a composite film that was able to sense liquefied petroleum gases

Conjugation of Biological and Carbon Nanoparticles For Applications In Electronics and Cell Imaging

The formation of 1-dimensional inorganic architectures using biological particles as templates has led to the development of composite nanomaterial assemblies with well defined structures and compositions. This paper reports an improvement of the method of mineralization of viruses and virus-like particles based on a two-step chemical modification via click chemistry to introduce a pyridine-based ligand scaffold to the exterior of the protein surface of the tobacco mosaic virus (TMV). This ligand system shows an increase of the surface coverage of the virus, as well as highly ordered crystalline organization over large areas without the need for time consuming genetic modifications to the protein coat. Quantum dots have been extensively studied for applications in cancer cell targeting, imaging, and drug delivery. Carbon-based quantum dots, or Selah Dots, were conjugated with fluorescent dye molecules to improve their fluorescent signal, and cell targeting ligands were conjugated to improve the cell targeting specificity. Preliminary results of cancer cell targeting show that conjugation of these ligands and fluorophores improve the target specificity and enhance the fluorescent signal