Опыт применения актовегина у пациента с когнитивными расстройствами при сахарном диабете (клиническое наблюдение)

Diabetic encephalopathy is one of the late complications of diabetes mellitus arising from chronic hyperglycemia and cerebral macro- and microangiopathy. Cognitive impairment developing during diabetic encephalopathy and the associated maladaptation of patients become even more socially significant due to the rapid increase in the number of patients suffering from diabetes mellitus. In this regard, studies of drugs that improve cognitive functions in patients with diabetes mellitus are of the particular importance. Clinical case of a patient with cognitive impairment and diabetes mellitus treated with actovegin describes its effect on glucose utilization, as well as antioxidant, antihypoxant and other mechanisms of action that allow the drug to be used in patients with cognitive impairment CI on the background of diabetes mellitus.Диабетическая энцефалопатия – одно из поздних осложнений сахарного диабета, возникающее вследствие хронический гипергликемии и, как следствие, церебральной макро- и микроангиопатии. Когнитивные расстройства при диабетической энцефалопатии и связанная с ними дезадаптация больных приобретают большую социальную значимость в связи со стремительным ростом популяции пациентов, страдающих сахарным диабетом. Особую важность приобретают исследования препаратов, улучшающих когнитивные функции у таких больных. В статье представлено клиническое наблюдение пациентки с когнитивными расстройствами на фоне сахарного диабета, получавшей лечение актовегином. Описано влияние препарата на утилизацию глюкозы, антиоксидантный, антигипоксантный и другие механизмы действия, позволяющие использовать терапию у пациентов с когнитивными расстройствами на фоне сахарного диабета

Pancakes for a healthy diet: low-carb, prebiotic, gluten-free

The work aims to develop pancake recipes corresponding to the standards of a healthy diet by replacing traditional components with ingredients containing nutritional functional properties. Corn and rice flour are gluten-free and can be used to design gluten-free pancakes. Barley flour contains beta-glucans, a large amount of fiber, reduces the glycemic index of products, is useful not only for a healthy diet but also for people suffering from diabetes and obesity. Rye flour is low in calories, as millet flour contains dietary fiber, vitamins, and lowers cholesterol. Dietary fiber and inulin contribute to the regulation of intestinal microbiota. The results show the possibility of 100% replacement of wheat flour with other types of flour in the production of low-carb, prebiotic, and gluten-free pancakes. The water absorption capacity of flour, dough viscosity, humidity, texture of products, and sensory analysis of finished products were investigated. Replacing wheat flour with alternative types of flour can improve the nutritional value of products, increase the content of dietary fiber, and reduce the calorie content of pancakes

Elasticity Theory Connection Rules for Epitaxial Interfaces

Elasticity theory provides an accurate description of the long-wavelength vibrational dynamics of homogeneous crystalline solids, and with supplemental boundary conditions on the displacement field can also be applied to abrupt heterojunctions and interfaces. The conventional interface boundary conditions, or connection rules, require that the displacement field and its associated stress field be continuous through the interface. We argue, however, that these boundary conditions are generally incorrect for epitaxial interfaces, and we give the general procedure for deriving the correct conditions, which depend essentially on the detailed microscopic structure of the interface. As a simple application of our theory we analyze in detail a one-dimensional model of an inhomogeneous crystal, a chain of harmonic oscillators with an abrupt change in mass and spring stiffness parameters. Our results have implications for phonon dynamics in nanostructures such as superlattices and nanoparticles, as well as for the thermal boundary resistance at epitaxial interfaces.Comment: 7 pages, Revte

New Mechanism for Electronic Energy Relaxation in Nanocrystals

The low-frequency vibrational spectrum of an isolated nanometer-scale solid differs dramatically from that of a bulk crystal, causing the decay of a localized electronic state by phonon emission to be inhibited. We show, however, that an electron can also interact with the rigid translational motion of a nanocrystal. The form of the coupling is dictated by the equivalence principle and is independent of the ordinary electron-phonon interaction. We calculate the rate of nonradiative energy relaxation provided by this mechanism and establish its experimental observability.Comment: 4 pages, Submitted to Physical Review

AlGaAs/GaAs Quantum Well Infrared Photodetectors

In this article, we present an overview of a focal plane array (FPA) with 640 × 512 pixels based on the AlGaAs quantum well infrared photodetector (QWIP). The physical principles of the QWIP operation and their parameters for the spectral range of 8–10 μm have been discussed. The technology of the manufacturing FPA based on the QWIP structures with the pixels 384 × 288 and 640 × 512 has been demonstrated. The parameters of the manufactured 640 × 512 FPA with a step of 20 μm have been given. At the operating temperature of 72 K, the temperature resolution of QWIP focal plane arrays is less than 35 mK. The number of defective elements in the matrix does not exceed 0.5%. The stability and uniformity of the FPA have been demonstrated

Studying the initial stage of nucleation with low-frequency Raman scattering

The objective of this paper is to show that low-frequency Raman scattering appears to be a sensitive method for the investigation of the initial stage of nucleation in multi- and mono-component systems. In the case of the mono-component systems, when the crystalline nuclei do not have an acoustic mismatch as compared to the amorphous matrix, we cannot observe their surface vibrations, but we can make use of the fact that in nucleation there is a jump in a structure correlation length. This results in a sharp decrease in contribution to the density of the acoustic vibration states because of decreasing the concentration of structural correlations on which acoustic phonons are localized. In addition, low-frequency Raman spectroscopy may be useful in the research into the phase transformation in materials for phase-change memories

Experience of actovegin use in a patient with cognitive impairment in diabetes mellitus (clinical case)

Diabetic encephalopathy is one of the late complications of diabetes mellitus arising from chronic hyperglycemia and cerebral macro- and microangiopathy. Cognitive impairment developing during diabetic encephalopathy and the associated maladaptation of patients become even more socially significant due to the rapid increase in the number of patients suffering from diabetes mellitus. In this regard, studies of drugs that improve cognitive functions in patients with diabetes mellitus are of the particular importance. Clinical case of a patient with cognitive impairment and diabetes mellitus treated with actovegin describes its effect on glucose utilization, as well as antioxidant, antihypoxant and other mechanisms of action that allow the drug to be used in patients with cognitive impairment CI on the background of diabetes mellitus