Inverting the model of genomics data sharing with the NHGRI Genomic Data Science Analysis, Visualization, and Informatics Lab-space

The NHGRI Genomic Data Science Analysis, Visualization, and Informatics Lab-space (AnVIL; https://anvilproject.org) was developed to address a widespread community need for a unified computing environment for genomics data storage, management, and analysis. In this perspective, we present AnVIL, describe its ecosystem and interoperability with other platforms, and highlight how this platform and associated initiatives contribute to improved genomic data sharing efforts. The AnVIL is a federated cloud platform designed to manage and store genomics and related data, enable population-scale analysis, and facilitate collaboration through the sharing of data, code, and analysis results. By inverting the traditional model of data sharing, the AnVIL eliminates the need for data movement while also adding security measures for active threat detection and monitoring and provides scalable, shared computing resources for any researcher. We describe the core data management and analysis components of the AnVIL, which currently consists of Terra, Gen3, Galaxy, RStudio/Bioconductor, Dockstore, and Jupyter, and describe several flagship genomics datasets available within the AnVIL. We continue to extend and innovate the AnVIL ecosystem by implementing new capabilities, including mechanisms for interoperability and responsible data sharing, while streamlining access management. The AnVIL opens many new opportunities for analysis, collaboration, and data sharing that are needed to drive research and to make discoveries through the joint analysis of hundreds of thousands to millions of genomes along with associated clinical and molecular data types

The Value of the First Amendment

Geoffrey Stone, a constitutional scholar and professor at the University of Chicago Law School, joins Charles Overby in a conversation about press freedoms and the First Amendment

Bill Rose Tells All

Bill Rose, a prize-winning journalist who retired in 2018 as an Overby Fellow, makes a valedictory appearance to talk about his long and colorful career in the second of the Overby Center for Southern Journalism and Politics’ 2018 spring schedule. Charles Overby, chairman of the center, conducts the conversation with Rose, his friend and colleague for many years. A native of Shelby, Miss., Rose graduated from Ole Miss in 1969 and went to work for the Delta Democrat-Times in Greenville before moving on to two prominent newspapers in Florida. He served as a reporter and editor at the Miami Herald, where he was engaged in numerous prize-winning projects. As a reporter, he covered city and county government before being assigned to the Herald’s Atlanta bureau where his beat was expanded to the entire South. After five years, he went back to Miami as deputy city editor and national editor, then took over as editor of Tropic, the Herald’s Sunday magazine which won two Pulitzer Prizes. He later moved up the coast to serve as managing editor at the Palm Beach Post, where he presided over numerous new prizes. Following his retirement and return to Mississippi, Rose was named a fellow at the Overby Center in 2011 and also joined the faculty of the Meek School of Journalism and New Media. He directed a special writing program that produced student magazines that concentrated on life in the Mississippi Delta and won three times the prestigious Robert F. Kennedy Human Rights Journalism Award, a national honor. In 2015, Rose was given a Silver Em, the highest honor the Ole Miss journalism school awards to people in the profession with Mississippi backgrounds. Bill has had one of the most accomplished careers of any living Mississippi journalists,” said Overby. “We look forward to hearing some of the many stories that he knows about journalists, politicians and Southern life.

Land of Broken Promises

An in-depth look in words and pictures at the legacy of the Voting Rights Act of 1965 in the Mississippi Delta by a panel of students who reported in the Delta under the direction of Overby Fellow Bill Rose, interviewing local officials, former civil rights workers and movement legends such as Andrew Young and John Lewis. Read the digital copy of the magazine her

The Importance of Independent Judges

Jim Duff, who oversees the nation’s federal courts, discusses important issues relating to federal judges, including the importance of independent judges. The former CEO of the Newseum is interviewed by Charles Overby, the first CEO of the Newseum, in a conversation that covers a wide range of issues involving courts, the media and constitutional freedoms

Assassins, Eccentrics, Politicians, and Other Persons of Interest

Overby Fellow Curtis Wilkie discusses his new book, a collection of 50 stories taken from his long career as a newspaper reporter covering the civil rights movement, national politics, conflicts in the Middle East and unique tales in the South, with Charles Overby. The book is being published by the University Press of Mississippi

Mississippians Say the Strangest Things

In a conversation with the Overby Center for Southern Journalism and Politics chairman, Charles Overby, David Crews elaborates on his recently published “The Mississippi Book of Quotations” in the fourth of a spring series of programs dedicated to Mississippi during the celebration of its 200th anniversary of statehood

Jack Ford

Jack Ford speaks to journalism and marketing students at the Meek School of Journalism and New Media

Free State of Jones

A rebellion against the Confederacy by poor white farmers in Jones County loyal to the Union, joined by a few former slaves, led to the establishment of the “Free State of Jones” during the Civil War, and the episode is the focus of a discussion by two prominent Jones County natives, retired U.S. District Judge Charles Pickering and Jones County Junior College history instructor Wyatt Moulds, and Charles Overby, chairman of the host Overby Center for Southern Journalism and Politics at Ole Miss

Crime and Punishment

John Hailman, a veteran prosecutor in the U.S. Attorney\u27s office for North Mississippi who wrote a book about his experiences, From Midnight to Guntown: True Crime Stories from a Federal Prosecutor in Mississippi