잡견에 식립된 서로 다른 직경의 TiO2 나노튜브 표면 처리된 임플란트의 조직계측학적 연구

Dept. of Dental Science/박사Implant systems available today present several types of surface treatment with the aim to optimize osseointegration. The purpose of this study was to evaluate surface-treated implant with different size of TiO2 nanotubes on the osseointegration in mongrel dog. In this study, five dogs were selected and a total of 80 titanium implants were placed in both maxilla and mandible. Eight weeks after extraction, 16 internal type implants with different surface treatments were placed for each mongrel dog, having 4 implants at all quadrants. Resorbable blasted media(RBM) surfaced implants were used as a control group and implants which were surface-treated with various diameter of nanotubes (30 nm, 70 nm, 100 nm) were used as experimental groups. The dogs were sacrificed at 4 weeks and 12 weeks after implantation. Removal torque test (removal torque value; RTV) and histomorphometric analysis (Bone-to-Implant contact; BIC, bone volume; BV) were performed, and Kruskall-wallis test was used for statistical analysis. The results from removal torque test were as follows: (RTV; Group Mean SD; 4 weeks: RBM (control)16.92±5.12, 30 nm(Exp 30) 26.18±5.11, 70 nm(Exp 70): 21.78±5.39, 100 nm(Exp 100): 20.30±5.18, 12 weeks; 21.40±9.22, 36.58±5.99, 37.42±9.23, 29.40±2.57). The results from removal torque test did not show statistically significant difference. The results from histomorphometric analysis were as follows: (BIC Group Mean SD; 4 weeks: 31.42±4.67, 28.37±8.69, 27.96±4.78, 35.58±9.36, 12 weeks: 37.53±1.67, 38.44±8.59, 32.38±7.36, 41.51±9.53), (BV Group Mean SD; 4 weeks: 40.72±9.15, 39.87±2.98, 44.92±10.20, 46.64±4.54, 12 weeks: 51.75±3.28, 57.49±4.11, 58.86±5.58, 54.99±5.99). The results from histomorphometric analysis did not show statistically significant difference.Within the limitation of this study, all experimental groups showed a greater RTV than control group. From histomorphometric analysis, 100 nm experimental group displayed the highest BIC value of all other experimental group and control group and BV value was highest in 100 nm experimental group sacrificed at 4 weeks and 70 nm experimental group sacrificed at 12 weeks. There is also a tendency of increased RTV, BIC and BV values in 12 week group compared to corresponding 4 week group.restrictio

Quality of life in the general population of Mongolia: Normative data on WHOQOL-BREF.

No data on the quality of life (QOL) of the general population are available for Mongolia. This study aimed to determine normative data on the World Health Organization Quality of Life-Brief Version (WHOQOL-BREF) in the general population of Mongolia. This nationwide, population-based, cross-sectional study was conducted in 48 sampling centers across Mongolia in 2020. We used the WHOQOL-BREF and the Hospital Anxiety and Depression Scale (HADS) in our study and evaluated their associations with vital signs, body measurements, and lifestyle determinants. A total of 714 participants (261 men and 453 women) with a mean (standard deviation) age of 40.7 (13.2) years were recruited. The mean scores of WHOQOL-BREF subscales were 61.5 for physical health, 73.5 for psychological health, 70.1 for social relationship, and 67.2 for environmental health domains. The prevalence of poor QOL was 16.9% among the participants. Participants living in an apartment in urban areas with high HADS scores had a low QOL. All domains of WHOQOL-BREF were inversely correlated with anxiety score (r = -0.353 - -0.206, p < 0.001) and depression scores (r = -0.335 - -0.156, p < 0.001). Physical health was predicted by residency location, anxiety, and depression (R2 = 0.200, p < 0.001); psychological health by anxiety and depression (R2 = 0.203, p < 0.001); social relationship by residency location, age group, anxiety and depression (R2 = 0.116, p < 0.001); and environmental health by employment, anxiety, and depression (R2 = 0.117, p < 0.001). This is the first report on normative data on the QOL in the general population of Mongolia. Physical health was low compared with that determined using international data. Poor QOL was observed among those with mental health issues living in the urban areas