Acute Stroke Multimodal Imaging: Present and Potential Applications toward Advancing Care.

In the past few decades, the field of acute ischemic stroke (AIS) has experienced significant advances in clinical practice. A core driver of this success has been the utilization of acute stroke imaging with an increasing focus on advanced methods including multimodal imaging. Such imaging techniques not only provide a richer understanding of AIS in vivo, but also, in doing so, provide better informed clinical assessments in management and treatment toward achieving best outcomes. As a result, advanced stroke imaging methods are now a mainstay of routine AIS practice that reflect best practice delivery of care. Furthermore, these imaging methods hold great potential to continue to advance the understanding of AIS and its care in the future. Copyright © 2017 by Thieme Medical Publishers, Inc

Self-reported and parent-reported mental health in children from low income families in Agder, Norway : results from baseline measurements of New Patterns project participants

Acknowledgments We would like to thank master’s students Vilde Johanna Solheim Lie, Hedda Andrea Struksnæs Sørdal and HAO whose theses in clinical psychology at the University of Bergen functioned as a first draft to this article. We would like to thank the participants and acknowledge the New Patterns project family coordinators who conducted the mapping and supported the participants over time. Funding The work was partly funded by a grant from the Research Council of Norway (number 295686).Peer reviewedPublisher PD

Scale invariance and universality of force networks in static granular matter

Force networks form the skeleton of static granular matter. They are the key ingredient to mechanical properties, such as stability, elasticity and sound transmission, which are of utmost importance for civil engineering and industrial processing. Previous studies have focused on the global structure of external forces (the boundary condition), and on the probability distribution of individual contact forces. The disordered spatial structure of the force network, however, has remained elusive so far. Here we report evidence for scale invariance of clusters of particles that interact via relatively strong forces. We analyzed granular packings generated by molecular dynamics simulations mimicking real granular matter; despite the visual variation, force networks for various values of the confining pressure and other parameters have identical scaling exponents and scaling function, and thus determine a universality class. Remarkably, the flat ensemble of force configurations--a simple generalization of equilibrium statistical mechanics--belongs to the same universality class, while some widely studied simplified models do not.Comment: 15 pages, 4 figures; to appear in Natur

Comparing the face inversion effect in crows and humans

Humans show impaired recognition of faces that are presented upside down, a phenomenon termed face inversion effect, which is thought to reflect the special relevance of faces for humans. Here, we investigated whether a phylogenetically distantly related avian species, the carrion crow, with similar socio-cognitive abilities to human and non-human primates, exhibits a face inversion effect. In a delayed matching-to-sample task, two crows had to differentiate profiles of crow faces as well as matched controls, presented both upright and inverted. Because crows can discriminate humans based on their faces, we also assessed the face inversion effect using human faces. Both crows performed better with crow faces than with human faces, and performed worse when responding to inverted pictures in general compared to upright pictures. However, neither of the crows showed a face inversion effect. For comparative reasons, the tests were repeated with human subjects. As expected, humans showed a face-specific inversion effect. Therefore, we did not find any evidence that crows – like humans – process faces as a special visual stimulus. Instead, individual recognition in crows may be based on cues other than a conspecific’s facial profile, such as their body, or on processing of local features rather than holistic processing.This work was supported by Ph.D scholarships from the Cambridge Commonwealth, European and International Trust and Lucy Cavendish College Cambridge (KFB),  a DFG Grant NI 618/7-1 (AN), and by the European Research Council, Grant Agreement No. 3399933 (LO, NSC)

Update of the LHC Arc Cryostat Systems Layouts and Integration

Since the LHC Conceptual Design report's publication in October 1995 [1], and subsequent evolutions [2], the LHC Arc Cryostat System has undergone recently a number of significant changes, dictated by the natural evolution of the project. Most noteworthy are the recent decisions to route the large number of auxiliary circuits feeding the arc corrector magnets in a separate tube placed inside the cryostat with connections to the magnets every half-cell. Further decisions concern simplification of the baseline vacuum and cryogenic sectorization, the finalization of the design of the arc cryogenic modules and the layout of the arc electrical distribution feedboxes. The most recent features of the highly intricate cryogenics, magnetic, vacuum and electrical distribution systems of the LHC are presente

The super-LHC

We review here the prospects of a long-term upgrade programme for the Large Hadron Collider (LHC), CERN laboratory's new proton-proton collider. The super-LHC, which is currently under evaluation and design, is expected to deliver of the order of ten times the statistics of the LHC. In addition to a non-technical summary of the principal physics arguments for the upgrade, I present a pedagogical introduction to the technological challenges on the accelerator and experimental fronts, and a review of the current status of the planning.Comment: To appear in Contemporary Physic

Performance of the 1-m Model of the 6 kA Superconducting Quadrupole for the LHC Insertions

The LHC dispersion suppressors and matching sections will be equipped with individually powered superconducting quadrupoles with an aperture of 56 mm. In order to minimise the cost of the powering circuits, the quadrupole has been designed on the basis of an 8 mm wide NbTi Rutherford-type cable for a nominal current of 5300 A, corresponding to a gradient of 200 T/m at 1.9 K. In order to validate the design options a model magnet program has been launched. In this report we describe the construction features of the first 1-m long magnet, and present its training performance and the results of protection studies

Prospective analysis of the influence of sport and educational factors on the prevalence and initiation of smoking in older adolescents from Croatia

The prevalence of smoking among Croatian adolescents is alarmingly high, but no previous study has prospectively examined the sport- and academic-factors associated with smoking and smoking initiation. This study aimed to prospectively examine the associations between scholastic (educational) achievement and sport factors and smoking in 16- to 18-year-old adolescents. This twoyear prospective cohort study included 644 adolescents who were 16 years of age at baseline (46% females). Baseline testing was implemented at the beginning of the 3rd year of high school (September 2014) when participants were 16 years old. Follow-up testing was completed at the end of the fourth year of high school, which occurred 20 months later. The evaluated predictor variables were educational-achievement- and sport-related-factors. The outcome variables were (i) smoking at baseline; (ii) smoking at follow-up; and (iii) smoking initiation over the course of the study. We assessed the associations between predictors and outcomes using logistic regression models adjusted for age, gender, socioeconomic status, and conflict with parents. The educational variables were consistently associated with smoking, with lower grade-point-average (Baseline: odd ratio (OR): 2.01, 95% confidence interval (CI): 1.61\u20132.55; Follow-up: 1.59, 1.31\u20131.94), more frequent absence from school (Baseline: OR: 1.40, 95% CI: 1.19\u20131.69; Follow-up: 1.30, 1.08\u20131.58), and lower behavioral grades (Baseline: OR: 1.80, 95% CI: 1.10\u20132.89; Follow-up: 1.57, 1.03\u20132.41) in children who smoke. Adolescents who reported quitting sports were at greater odds of being smokers (Baseline: 2.07, 1.31\u20133.32; Followup: 1.66, 1.09\u20132.56). Sport competitive achievement at baseline was protective against smoking initiation during following two-year period (0.45, 0.21\u20130.91). While the influence of the educational variables on smoking initiation has been found to be established earlier; sport achievement was identified as a significant protective factor against initiating smoking in older adolescents. Results should be used in development of an anti-smoking preventive campaign in older adolescents

Design, Fabrication and Initial Testing of a Large Bore Single Aperture 1 m Long Superconducting Dipole Made with Phenolic Inserts

In the framework of the LHC magnet development programme, a large bore single aperture 1-meter long superconducting dipole has been built in collaboration with HOLEC. The magnet features a single layer coil wound using the LHC main dipole outer layer cable, phenolic inserts, and a keyed two part structural iron yoke. This paper presents the magnetic and mechanical design and optimisation of the magnet. We describe the coil winding and curing, and present the construction and assembly procedures. Finally we report on the mechanical behaviour during assembly and cooling, and present the magnet training behaviour