3 research outputs found

    Application of Nanocomposite Coatings with Different Structural Physical and Chemical Characteristics in Tissue Engineering

    Get PDF
    The research covers the results of experimental studies of the effect character of nanocomposite coatings with different physical and chemical parameters (type, roughness, hydrophilic-hydrophobic characteristics) on structural and functional properties (adhesive potential, phenotype, gene expression) of mesenchymal stem cells (MSCs). On the tested nanocoatings (Al2O3, ZrO2, Ta2O5) the capability of oxide coating Al2O3 to enrich the in vitro cultured bone marrow (BM) with the cells of MSCs phenotype markers as well as to increase the expression rate of ido gene in them, which may extend the spectrum of their therapeutic application in clinics, has been found. When you are citing the document, use the following link http://essuir.sumdu.edu.ua/handle/123456789/3496

    Application of Nanocomposite Coatings with Different Structural Physical and Chemical Characteristics in Tissue Engineering

    Get PDF
    The research covers the results of experimental studies of the effect character of nanocomposite coatings with different physical and chemical parameters (type, roughness, hydrophilic-hydrophobic characteristics) on structural and functional properties (adhesive potential, phenotype, gene expression) of mesenchymal stem cells (MSCs). On the tested nanocoatings (Al2O3, ZrO2, Ta2O5) the capability of oxide coating Al2O3 to enrich the in vitro cultured bone marrow (BM) with the cells of MSCs phenotype markers as well as to increase the expression rate of ido gene in them, which may extend the spectrum of their therapeutic application in clinics, has been found. When you are citing the document, use the following link http://essuir.sumdu.edu.ua/handle/123456789/3496

    ИспользованиС Π½Π°Π½ΠΎΠΊΠΎΠΌΠΏΠΎΠ·ΠΈΡ‚Π½Ρ‹Ρ… ΠΏΠΎΠΊΡ€Ρ‹Ρ‚ΠΈΠΉ с Ρ€Π°Π·Π»ΠΈΡ‡Π½Ρ‹ΠΌΠΈ Ρ„ΠΈΠ·ΠΈΠΊΠΎ-химичСскими характСристиками Π² Ρ‚ΠΊΠ°Π½Π΅Π²ΠΎΠΉ ΠΈΠ½ΠΆΠ΅Π½Π΅Ρ€ΠΈΠΈ

    No full text
    The research covers the results of experimental studies of the effect character of nanocomposite coatings with different physical and chemical parameters (type, roughness, hydrophilic-hydrophobic characteristics) on structural and functional properties (adhesive potential, phenotype, gene expression) of mesenchymal stem cells (MSCs). On the tested nanocoatings (Al2O3, ZrO2, Ta2O5) the capability of oxide coating Al2O3 to enrich the in vitro cultured bone marrow (BM) with the cells of MSCs phenotype markers as well as to increase the expression rate of ido gene in them, which may extend the spectrum of their therapeutic application in clinics, has been found. ΠŸΡ€ΠΈ Ρ†ΠΈΡ‚ΡƒΠ²Π°Π½Π½Ρ– Π΄ΠΎΠΊΡƒΠΌΠ΅Π½Ρ‚Π°, використовуйтС посилання http://essuir.sumdu.edu.ua/handle/123456789/30946Π£ Ρ€ΠΎΠ±ΠΎΡ‚Ρ– прСдставлСно Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚ΠΈ Π΅ΠΊΡΠΏΠ΅Ρ€ΠΈΠΌΠ΅Π½Ρ‚Π°Π»ΡŒΠ½ΠΈΡ… Π΄ΠΎΡΠ»Ρ–Π΄ΠΆΠ΅Π½ΡŒ Ρ…Π°Ρ€Π°ΠΊΡ‚Π΅Ρ€Ρƒ Π²ΠΏΠ»ΠΈΠ²Ρƒ Π½Π°Π½ΠΎΠΊΠΎΠΌΠΏΠΎΠ·ΠΈΡ‚Π½ΠΈΡ… ΠΏΠΎΠΊΡ€ΠΈΡ‚Ρ‚Ρ–Π² Π· Ρ€Ρ–Π·Π½ΠΈΠΌΠΈ Ρ„Ρ–Π·ΠΈΠΊΠΎ-Ρ…Ρ–ΠΌΡ–Ρ‡Π½ΠΈΠΌΠΈ ΠΏΠ°Ρ€Π°ΠΌΠ΅Ρ‚Ρ€Π°ΠΌΠΈ (Ρ‚ΠΈΠΏ, ΡˆΠΎΡ€ΡΡ‚ΠΊΡ–ΡΡ‚ΡŒ, Π³Ρ–Π΄Ρ€ΠΎΡ„Ρ–Π»ΡŒΠ½ΠΎ-Π³Ρ–Π΄Ρ€ΠΎΡ„ΠΎΠ±Π½Ρ– характСристики) Π½Π° структурні ΠΉ Ρ„ΡƒΠ½ΠΊΡ†Ρ–ΠΎΠ½Π°Π»ΡŒΠ½Ρ– властивості (Π°Π΄Π³Π΅Π·ΠΈΠ²Π½ΠΈΠΉ ΠΏΠΎΡ‚Π΅Π½Ρ†Ρ–Π°Π», фСнотипія, СкспрСсія Π³Π΅Π½Ρ–Π²) ΠΌΠ΅Π·Π΅Π½Ρ…Ρ–ΠΌΠ°Π»ΡŒΠ½ΠΈΡ… ΡΡ‚Ρ€ΠΎΠΌΠ°Π»ΡŒΠ½ΠΈΡ… ΠΊΠ»Ρ–Ρ‚ΠΈΠ½ (МБК). Π†Π· ΡƒΡΡŒΠΎΠ³ΠΎ спСктра Π°ΠΏΡ€ΠΎΠ±ΠΎΠ²Π°Π½ΠΈΡ… Π½Π°Π½ΠΎΠΏΠΎΠΊΡ€ΠΈΡ‚Ρ‚Ρ–Π² (Al2O3, Zr2, Ta2O5) встановлСна Π·Π΄Π°Ρ‚Π½Ρ–ΡΡ‚ΡŒ оксидного покриття Аl2O3 Π·Π±Π°Π³Π°Ρ‡ΡƒΠ²Π°Ρ‚ΠΈ ΠΊΡƒΠ»ΡŒΡ‚ΠΈΠ²ΠΎΠ²Π°Π½ΠΈΠΉ in vitro кістковий ΠΌΠΎΠ·ΠΎΠΊ (КМ) ΠΊΠ»Ρ–Ρ‚ΠΈΠ½Π°ΠΌΠΈ Π· Ρ„Π΅Π½ΠΎΡ‚ΠΈΠΏΡ–Ρ‡Π½ΠΈΠΌΠΈ ΠΌΠ°Ρ€ΠΊΠ΅Ρ€Π°ΠΌΠΈ МБК, Π° Ρ‚Π°ΠΊΠΎΠΆ ΠΏΡ–Π΄Π²ΠΈΡ‰ΡƒΠ²Π°Ρ‚ΠΈ ΡΡ‚ΡƒΠΏΡ–Π½ΡŒ СкспрСсії Π² Π½ΠΈΡ… Π³Π΅Π½Π° ido, Ρ‰ΠΎ ΠΌΠΎΠΆΠ΅ Ρ€ΠΎΠ·ΡˆΠΈΡ€ΡŽΠ²Π°Ρ‚ΠΈ спСктр Ρ—Ρ…Π½ΡŒΠΎΠ³ΠΎ Ρ‚Π΅Ρ€Π°ΠΏΠ΅Π²Ρ‚ΠΈΡ‡Π½ΠΎΠ³ΠΎ застосування Π² ΠΊΠ»Ρ–Π½Ρ–Ρ‡Π½Ρ–ΠΉ ΠΏΡ€Π°ΠΊΡ‚ΠΈΡ†Ρ–. ΠŸΡ€ΠΈ Ρ†ΠΈΡ‚ΠΈΡ€ΠΎΠ²Π°Π½ΠΈΠΈ Π΄ΠΎΠΊΡƒΠΌΠ΅Π½Ρ‚Π°, ΠΈΡΠΏΠΎΠ»ΡŒΠ·ΡƒΠΉΡ‚Π΅ ссылку http://essuir.sumdu.edu.ua/handle/123456789/30946Π’ Ρ€Π°Π±ΠΎΡ‚Π΅ прСдставлСны Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹ ΡΠΊΡΠΏΠ΅Ρ€ΠΈΠΌΠ΅Π½Ρ‚Π°Π»ΡŒΠ½Ρ‹Ρ… исслСдований Ρ…Π°Ρ€Π°ΠΊΡ‚Π΅Ρ€Π° влияния Π½Π°Π½ΠΎΠΊΠΎΠΌΠΏΠΎΠ·ΠΈΡ‚Π½Ρ‹Ρ… ΠΏΠΎΠΊΡ€Ρ‹Ρ‚ΠΈΠΉ с Ρ€Π°Π·Π»ΠΈΡ‡Π½Ρ‹ΠΌΠΈ Ρ„ΠΈΠ·ΠΈΠΊΠΎ-химичСскими ΠΏΠ°Ρ€Π°ΠΌΠ΅Ρ‚Ρ€Π°ΠΌΠΈ (Π²ΠΈΠ΄, ΡˆΠ΅Ρ€ΠΎΡ…ΠΎΠ²Π°Ρ‚ΠΎΡΡ‚ΡŒ, Π³ΠΈΠ΄Ρ€ΠΎΡ„ΠΈΠ»ΡŒΠ½ΠΎ-Π³ΠΈΠ΄Ρ€ΠΎΡ„ΠΎΠ±Π½Ρ‹Π΅ характСристики) Π½Π° структурныС ΠΈ Ρ„ΡƒΠ½ΠΊΡ†ΠΈΠΎΠ½Π°Π»ΡŒΠ½Ρ‹Π΅ свойства (Π°Π΄Π³Π΅Π·ΠΈΠ²Π½Ρ‹ΠΉ ΠΏΠΎΡ‚Π΅Π½Ρ†ΠΈΠ°Π», фСнотипия, экспрСссия Π³Π΅Π½ΠΎΠ²) ΠΌΠ΅Π·Π΅Π½Ρ…ΠΈΠΌΠ°Π»ΡŒΠ½Ρ‹Ρ… ΡΡ‚Ρ€ΠΎΠΌΠ°Π»ΡŒΠ½Ρ‹Ρ… ΠΊΠ»Π΅Ρ‚ΠΎΠΊ (МБК). Из всСго спСктра Π°ΠΏΡ€ΠΎΠ±ΠΈΡ€ΠΎΠ²Π°Π½Π½Ρ‹Ρ… Π½Π°Π½ΠΎΠΏΠΎΠΊΡ€Ρ‹Ρ‚ΠΈΠΉ (Al2O3, ZrO2, Ta2O5) установлСна ΡΠΏΠΎΡΠΎΠ±Π½ΠΎΡΡ‚ΡŒ оксидного покрытия Аl2O3 ΠΎΠ±ΠΎΠ³Π°Ρ‰Π°Ρ‚ΡŒ ΠΊΡƒΠ»ΡŒΡ‚ΠΈΠ²ΠΈΡ€ΡƒΠ΅ΠΌΡ‹ΠΉ in vitro костный ΠΌΠΎΠ·Π³ (КМ) ΠΊΠ»Π΅Ρ‚ΠΊΠ°ΠΌΠΈ с фСнотипичСскими ΠΌΠ°Ρ€ΠΊΠ΅Ρ€Π°ΠΌΠΈ МБК, Π° Ρ‚Π°ΠΊΠΆΠ΅ ΠΏΠΎΠ²Ρ‹ΡˆΠ°Ρ‚ΡŒ ΡΡ‚Π΅ΠΏΠ΅Π½ΡŒ экспрСссии Π² Π½ΠΈΡ… Π³Π΅Π½Π° ido, Ρ‡Ρ‚ΠΎ ΠΌΠΎΠΆΠ΅Ρ‚ Ρ€Π°ΡΡˆΠΈΡ€ΡΡ‚ΡŒ спСктр ΠΈΡ… тСрапСвтичСского примСнСния Π² клиничСской ΠΏΡ€Π°ΠΊΡ‚ΠΈΠΊΠ΅. When you are citing the document, use the following link http://essuir.sumdu.edu.ua/handle/123456789/3094
    corecore