A MILP model for an extended version of the Flexible Job Shop Problem

A MILP model for an extended version of the Flexible Job Shop Scheduling problem is proposed. The extension allows the precedences between operations of a job to be given by an arbitrary directed acyclic graph rather than a linear order. The goal is the minimization of the makespan. Theoretical and practical advantages of the proposed model are discussed. Numerical experiments show the performance of a commercial exact solver when applied to the proposed model. The new model is also compared with a simple extension of the model described by \"Ozg\"uven, \"Ozbakir, and Yavuz (Mathematical models for job-shop scheduling problems with routing and process plan flexibility, Applied Mathematical Modelling, 34:1539--1548, 2010), using instances from the literature and instances inspired by real data from the printing industry.Comment: 15 pages, 2 figures, 4 tables. Optimization Letters, 201

Outcomes in Newly Diagnosed Atrial Fibrillation and History of Acute Coronary Syndromes: Insights from GARFIELD-AF

BACKGROUND: Many patients with atrial fibrillation have concomitant coronary artery disease with or without acute coronary syndromes and are in need of additional antithrombotic therapy. There are few data on the long-term clinical outcome of atrial fibrillation patients with a history of acute coronary syndrome. This is a 2-year study of atrial fibrillation patients with or without a history of acute coronary syndromes