31 research outputs found
China-U.S. Potential Non-food Ethanol Exportation
To reduce national oil dependency, ethanol has been given a center stage of U.S. energy sources. The Renewable Fuel Standard (RFS) program was launched to increase the volume of renewable gasoline from 9 billion gallons in 2008 to 36 billion gallons by 2012, among which 15 billion are corn-based ethanol, while U.S. corn-based ethanol can hardly achieve this level. There is a trend that indicates U.S. importing ethanol from other countries, so a bilateral trade system has been established between U.S. and Brazil since 2003. The annual import is 211 million gallons in 2008 (USDC, 2009). Nevertheless, this amount is far away from the target, and the worldwide food shortage called us to divert our attention from fuel to food. China, as the third largest ethanol producer, has extreme ethanol growth potential with low production costs and large sources of cassava, which is a non-food feedstock for ethanol. This paper uses Data Envelopment Analysis (DEA) to measure and compare the efficiency of ethanol production in China and Brazil. To estimate the extent output can be proportionally expanded without altering the input quantities employed in each country. The output orientated method has been developed with annual ethanol production from the inputs-- land for ethanol crops, agricultural labor force and capacity of ethanol production. The DEA results show that China has been more efficient in ethanol production than Brazil since the year 2007. This means China has comparative advantage over Brazil in producing ethanol, hence U.S. can import from China instead of Brazil in the future.Ethanol, Efficiency, Non-food, Productivity, Feedstocks, Agricultural and Food Policy, International Relations/Trade, Productivity Analysis, Resource /Energy Economics and Policy,
A Foot and Mouth Disease Induced Model of US Excess Supply of Beef
Agriculture is a vulnerable sector of the U.S economy, accounting for 13% of Gross Domestic Product and 15% of employment. It produces quality cheap food for domestic consumption and accounts for more than 10.7 to $11.7 billion. The total cost of an FMD outbreak is the sum of eradication cost, production losses, and the loss of exports. This paper examines the export effects of a bioterrorist attack such as the introduction of FMD on the US beef industry. The context is to model the US beef market as a price taker on the international beef market, the simplifying “small open economy” assumption of international economics. Although, the beef market is linked to beef prices around the world, we tend to conceive of the US beef market in terms of domestic supply and demand and the resulting domestic equilibrium price. The excess supply of beef is the difference between quantities supplied and demanded that increases with price and responds to other influences on domestic supply and demand. We assumed that U.S consumers will exercise more caution when purchasing beef at grocery store as a result of the outbreak of FMD. As U.S consumers alter their diet, poultry and pork will become good substitutes with poultry having a higher demand than pork. The economic impact of FMD is simulated based on expected changes in price of beef and its substitutes based on three different scenarios of the levels of FMD occurrences.Excess supply, FMD, beef prices, bioterrorism, Agricultural and Food Policy, Environmental Economics and Policy, International Relations/Trade, Q17,
BSE and the US Economy: Input-Output Model Perspective
The potential impact of a BSE outbreak on the US economy is modeled in input-output setting using 2002 US IMPLAN data. An outbreak of BSE would hurt the US beef industry, other agriculturally-related industry, and the rest of the economy as a whole. The worse effects occur in the beef cattle and farming industries. Generally, the economy of every county would be hurt given the fact that cattle are produced in all the 50 states. But it is apparent that the damage would be substantial in those regions and households which already suffer the severest economic damage.Livestock Production/Industries,
Assisting Basic Six Pupils of Presbyterian Women’s College of Education Demonstration School, Aburi-Akuapem, To Discover the Product of Two Multi-Digit Multiplicands Using the Lattice
An action research was performed with the aim of solving problems involving two multi-digit multiplicands using the lattice to give pupils’ conceptual understanding of multiplication in basic six at the Presbyterian Women’s College of Education Demonstration School. Twenty-five pupils out of fifty (50) were selected using The simple random sampling technique from a combined class of Six ‘A’ and Six ‘B’ who have difficulties in answering questions under multiplication involving two multi-digit numbers, after writing a teacher made test (Pre-Test). The Pre- Test produced 16% pass mark as compared to the post-test which gave 88% pass mark after the intervention. The discovery method of teaching was used in the intervention procedure to find the multiplication of multi-digit numbers. Pupils were directed to use the lattice to perform activities which had the potential of developing their conceptual understanding of the topic. The data collected indicated that some pupils improved their understanding but some pupils needed more time to re-learn the subject. This research only presents some practical solutions proposed within the time available. Keywords: Action Research, Pre- Test, post-test, Multi-Digit Number
The Emergent Vinifera Wine Industry in North Carolina: A Descriptive Overview
The North Carolina (NC) wine industry has grown rapidly over the past decade and is expected to grow even more as the worldwide wine consumption and export of wines rises. In the United States, the wine market has grown by 13.7 percent since 2002 in volume and by more than 15 percent in dollars as wine has progressed from being a beverage of an elite segment of the market to becoming a mainline beverage, taking its place alongside beer and liquor (MKF Research LLC, 2007; Oches, 2009). The Piedmont Triad Region is uniquely positioned to increase its presence in this industry. Of the 80 wineries in NC that are currently open to the public, nearly half are located in the Piedmont Triad Region. However, growing grapes and making wine is a long term commitment to a community, both financially and physically. The MKF Research report states that the capital-intensive nature of the winery and vineyard sectors is often underestimated, with new entrants to the industry at times unprepared for the extended cash requirements. In addition, only a few local institutions are familiar with the unique needs of the winemaking business. In order to address factors that will impede growth in this nascent industry, it is important to identify the state of the industry and obtain management perspectives on the needs and challenges facing their operations. This study provides information that would help gain a better understanding of the business issues and needs related to the wine and grape industry in North Carolina. Data for this study was drawn from a census of 34 wine producers located in the Yadkin, Swan Creek, and the Haw River valley regions of North Carolina. Descriptive statistics using frequencies and means is used to provide a demographic overview of the industry and to identify the factors that wine producers perceive to be important in affecting their profitability. Results from the study shows that most of the wineries share some common traits: they are small, relatively new to the wine and grape industry and grow grapes other than the traditional native Muscadine grape. Primarily, a majority of the wineries are family-based entrepreneurial businesses that have to behave like mini-conglomerates. These findings are consistent with a study conducted by Taplin and Breckenridge (2008).Profitability Constraints, Financial Management, Marketing, Distribution, Agribusiness, Community/Rural/Urban Development, Farm Management,
Biomarkers of oxidative stress and its nexus with haemoglobin variants and adverse foeto-maternal outcome among women with preeclampsia in a Ghanaian population: A multi-centre prospective study
Introduction Haemoglobin variants and preeclampsia (PE) are associated with adverse fatal events of which oxidative stress may be an underlying factor. Oxidative stress (OS) among preeclamptic women with haemoglobin variants has been well established. It is, however, unclear whether haemoglobin variants induce OS to aggravate the risk of adverse foeto-maternal outcomes in pregnant women with preeclampsia. We measured the levels of OS biomarkers and determined the association between haemoglobin variants, and adverse foeto-maternal outcomes among pregnant women with PE. Methods This multi-centre prospective study recruited 150 PE women from three major health facilities in both Bono and Bono east regions of Ghana from April to December 2019. Haemoglobin variants; HbAS, HbSS, HbSC, HbCC, and HbAC were determined by haemoglobin electrophoresis. OS biomarkers such as malondialdehyde (MDA), catalase (CAT), vitamin C, and uric acid (UA) along with haematological and biochemical parameters were estimated using standard protocol. Adverse pregnancy complications (APCs) such as post-partum haemorrhage (PPH), HELLP (Haemolysis, Elevated liver enzymes, Low platelet count) syndrome, preterm delivery, neonatal intensive care unit (NICU) admission, and neonatal jaundice were recorded. Results Of the 150 pregnant women with preeclampsia, the distribution of haemoglobin AA, AS, AC, CC, SS and SC phenotypes were 66.0%, 13.3%, 12.7%, 3.3%, 3.3% and 1.3%, respectively. The most prevalent foeto-maternal outcomes among PE women were NICU admission (32.0%) followed by PPH (24.0%), preterm delivery (21.3%), HELLP syndrome (18.7%), and neonatal jaundice (18.0%). Except for vitamin C level which was significantly higher in patients with at least a copy of Haemoglobin S variant than those with at least a copy of Haemoglobin C variant (5.52 vs 4.55; p = 0.014), levels of MDA, CAT, and UA were not statistically significantly different across the various haemoglobin variants. Multivariate logistic regression model showed that participants with HbAS, HbAC, having at least a copy of S or C and participants with HbCC, SC, SS had significantly higher odds of neonatal jaundice, NICU admission, PPH and HELLP syndrome compared to participants with HbAA. Conclusion Reduced levels of vitamin C are common among preeclamptics with at least one copy of the HbC variant. Haemoglobin variants in preeclampsia contribute to adverse foeto-maternal outcomes with Haemoglobin S variants being the most influencing factor for PPH, HELLP, preterm labour, NICU admission, and neonatal jaundice
Prevalence and risk factors of obesity among undergraduate student population in Ghana: An evaluation study of body composition indices
Background: Obesity is a classified risk factor for several of the world’s leading causes of death. In this study, we combined information contained in body mass index (BMI), total percentage body fat (TPBF) and relative fat mass (RFM) to estimate obesity prevalence and examine the risk factors associated with obesity. Methods: The study recruited 1027 undergraduate students aged between 16 and 25 years using a cross-sectional study design and two-stage stratified random sampling between January and April 2019 from the Kwame Nkrumah University of Science and Technology, Kumasi, Ghana. Demographic, lifestyle, and family history of chronic disease data, were collected using a structured questionnaire. Bioelectrical impedance, along with height, weight, age, and gender, were used to estimate BMI and TPBF. The RFM was calculated using a published equation. The TPBF and RFM ranges were evaluated based on standard BMI thresholds and an informative combined obesity prevalence estimated in a Bayesian framework. Multiple logistic regression analysis was used to evaluate potential risk factors of overweight/obesity. Results: Concordance between BMI, TPBF and RFM for obesity classification was 84% among female and 82.9% among male students. The Bayesian analysis revealed a combined prevalence means of obesity of 9.4% (95%CI: 6.9-12.2%) among female students and 6.7% (95%CI:4.3-9.5%) among male students. The odds of obesity were increased between 1.8 and 2.5 for females depending on the classification index. A significant increasing trend of obesity was observed with university-level. A family history of obesity was associated with a high estimate of general, central, and high TPBF. Conclusion: Using multiple adiposity indicators conjointly in a Bayesian framework offers a greater power to examine obesity prevalence. We have applied this and reported high obesity prevalence, especially among female students. University level and family history of obesity were key determinants for obesity among the student population
The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance
INTRODUCTION
Investment in Africa over the past year with regard to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequencing has led to a massive increase in the number of sequences, which, to date, exceeds 100,000 sequences generated to track the pandemic on the continent. These sequences have profoundly affected how public health officials in Africa have navigated the COVID-19 pandemic.
RATIONALE
We demonstrate how the first 100,000 SARS-CoV-2 sequences from Africa have helped monitor the epidemic on the continent, how genomic surveillance expanded over the course of the pandemic, and how we adapted our sequencing methods to deal with an evolving virus. Finally, we also examine how viral lineages have spread across the continent in a phylogeographic framework to gain insights into the underlying temporal and spatial transmission dynamics for several variants of concern (VOCs).
RESULTS
Our results indicate that the number of countries in Africa that can sequence the virus within their own borders is growing and that this is coupled with a shorter turnaround time from the time of sampling to sequence submission. Ongoing evolution necessitated the continual updating of primer sets, and, as a result, eight primer sets were designed in tandem with viral evolution and used to ensure effective sequencing of the virus. The pandemic unfolded through multiple waves of infection that were each driven by distinct genetic lineages, with B.1-like ancestral strains associated with the first pandemic wave of infections in 2020. Successive waves on the continent were fueled by different VOCs, with Alpha and Beta cocirculating in distinct spatial patterns during the second wave and Delta and Omicron affecting the whole continent during the third and fourth waves, respectively. Phylogeographic reconstruction points toward distinct differences in viral importation and exportation patterns associated with the Alpha, Beta, Delta, and Omicron variants and subvariants, when considering both Africa versus the rest of the world and viral dissemination within the continent. Our epidemiological and phylogenetic inferences therefore underscore the heterogeneous nature of the pandemic on the continent and highlight key insights and challenges, for instance, recognizing the limitations of low testing proportions. We also highlight the early warning capacity that genomic surveillance in Africa has had for the rest of the world with the detection of new lineages and variants, the most recent being the characterization of various Omicron subvariants.
CONCLUSION
Sustained investment for diagnostics and genomic surveillance in Africa is needed as the virus continues to evolve. This is important not only to help combat SARS-CoV-2 on the continent but also because it can be used as a platform to help address the many emerging and reemerging infectious disease threats in Africa. In particular, capacity building for local sequencing within countries or within the continent should be prioritized because this is generally associated with shorter turnaround times, providing the most benefit to local public health authorities tasked with pandemic response and mitigation and allowing for the fastest reaction to localized outbreaks. These investments are crucial for pandemic preparedness and response and will serve the health of the continent well into the 21st century
A Proteomic Investigation Characterizing the Interactions and Posttranslational Modifications of the Interferon-Inducible Protein IFI16
The mammalian immune system has evolved multiple methods of combating
pathogens, with the detection of pathogenic nucleic acids being one of the first lines of
defense. Interferon-inducible protein IFI16 has become a focus of research in recent years
as a sensor of pathogenic DNA that is able to stimulate both a type I IFN response and a
proinflammatory response. Although it is mostly found in the nucleus, IFI16 has been
shown to sense DNA in the cytoplasm as well. Despite these findings, much about the
mechanisms regulating its ability to sense foreign DNA and distinguish it from host DNA
remains uncharacterized. In this study, a mass spectrometry-based approach was used to
gain a better understanding of IFI16’s function and role in innate immunity. IFI16 was
isolated in the nuclear and cytoplasmic fractions of differentiated THP-1 monocytes,
immunoaffinity purified and analyzed by tandem mass spectrometry in order to
determine its protein-protein interactions and posttranslational modifications. Here, it is
shown that the interactions of IFI16 in THP-1 cells differ from those of HEK293, which
is important given its function in the innate immune system. Additionally, IFI16 was
shown to interact with the cytoplasmic nucleic acid sensor LRRFIP1 and a repressing
factor of NF-κB (NKRF) in the nucleus. HERC5, an E3 ligase essential for the
conjugation of ISG15 was shown to specifically interact with IFI16 after IFN induction.
Finally, differential acetylations and phosphorylations were identified in the cytoplasmic
and nuclear fractions of THP-1 cells. Taken together, these data suggest that IFI16’s
interacting partners are cell-specific and localization-dependent and the same can be said
of its posttranslational modifications. Moreover, IFI16’s interactions are different in IFNinduced
cells, which speaks to the versatility of this pathogenic DNA sensor
Fee-based Services as Source of Funding for Public University Libraries in Ghana - A Survey
ABSTRACT
Academic libraries have a crucial role to play in the achievement of the goals of their parent institutions. However, public universities in Ghana have generally not been financing their libraries to the quantum that has been recommended by the Universities Rationalization Committee in Ghana. Public university libraries have experienced dwindling budgetary allocations which hover around 3% of the total universities’ annual budget. Responses received from a survey on sale of some aspect of their services as a possible source of additional income indicated that it exists only in one of the university libraries. Respondents posited that it is a potential source of additional funding to all three public university libraries - Kwame Nkrumah University of Science and Technology, University of Ghana and University of Cape Coast - involved in the survey. They however, indicated that the libraries’ mandate is not to dabble in sale of information. A policy direction on this subject is recommended for the libraries to take advantage of selling some aspects of services as good potential source of funding to help them solve their financial crisis