An organic Rankine receiver for the SCSTPE program

The organic Rankine cycle receiver which is presently being developed is described. The receiver employs an integrated cavity/pool boiler which permits the design of a small, lightweight, low cost and efficient moderate temperature receiver for use in a dish-Rankine solar thermal system

The Transition from Heavy Fermion to Mixed Valence in Ce1-xYxAl3: A Quantitative Comparison with the Anderson Impurity Model

We present a neutron scattering investigation of Ce1-xYxAl3 as a function of chemical pressure, which induces a transition from heavy-fermion behavior in CeAl3 (TK=5 K) to a mixed-valence state at x=0.5 (TK=150 K). The crossover can be modeled accurately on an absolute intensity scale by an increase in the k-f hybridization, Vkf, within the Anderson impurity model. Surprisingly, the principal effect of the increasing Vkf is not to broaden the low-energy components of the dynamic magnetic susceptibility but to transfer spectral weight to high energy.Comment: 4 pages, 5 figure

The 2+1 flavor topological susceptibility from the asqtad action at 0.06 fm

We report new data for the topological susceptibility computed on 2+1 flavor dynamical configurations with lattice spacing 0.06 fm, generated with the asqtad action. The topological susceptibility is computed by HYP smearing and compared with rooted staggered chiral perturbation theory as the pion mass goes to zero. At 0.06 fm, the raw data is already quite close to the continuum extrapolated values obtained from coarser lattices. These results provide a further test of the asqtad action with rooted staggered flavors.Comment: 7 pages, 5 figures, talk presented at the XXV International Symposium on Lattice Field Theory, July 30 - August 4, 2007, Regensburg, German

Microscopic eigenvalue correlations in QCD with imaginary isospin chemical potential

We consider the chiral limit of QCD subjected to an imaginary isospin chemical potential. In the epsilon-regime of the theory we can perform precise analytical calculations based on the zero-momentum Goldstone modes in the low-energy effective theory. We present results for the spectral correlation functions of the associated Dirac operators.Comment: 13 pages, 2 figures, RevTe

Decoupling a Cooper-pair box to enhance the lifetime to 0.2 ms

We present a circuit QED experiment in which a separate transmission line is used to address a quasi-lumped element superconducting microwave resonator which is in turn coupled to an Al/AlO$_{x}$/Al Cooper-pair box (CPB) charge qubit. In our measurements we find a strong correlation between the measured lifetime of the CPB and the coupling between the qubit and the transmission line. By monitoring perturbations of the resonator's 5.44 GHz resonant frequency, we have measured the spectrum, lifetime ($T_{1}$), Rabi, and Ramsey oscillations of the CPB at the charge degeneracy point while the CPB was detuned by up to 2.5 GHz . We find a maximum lifetime of the CPB was $T_{1} = 200\ \mu$s for $f = 4$ to 4.5 GHz. Our measured $T_{1}$'s are consistent with loss due to coupling to the transmission line, spurious microwave circuit resonances, and a background decay rate on the order of $5\times 10^{3}$ s$^{-1}$ of unknown origin, implying that the loss tangent in the AlO$_{x}$ junction barrier must be less than about $4\times 10^{-8}$ at 4.5 GHz, about 4 orders of magnitude less than reported in larger area Al/AlO$_{x}$/Al tunnel junctions

Baryon masses with improved staggered quarks

The MILC collaboration's simulations with improved staggered quarks are being extended with runs at a lattice spacing of 0.06 fm with quark masses down to one tenth the strange quark mass. We give a brief introduction to these new simulations and the determination of the lattice spacing. Then we combine these new runs with older results to study the masses of the nucleon and the Omega minus in the continuum and chiral limits.Comment: 7 pages, proceedings from Lattice 2007 conferenc

A CRISPR/Cas9-generated mutation in the zebrafish orthologue of PPP2R3B causes idiopathic scoliosis

Idiopathic scoliosis (IS) is the deformation and/or abnormal curvature of the spine that develops progressively after birth. It is a very common condition, affecting approximately 4% of the general population, yet the genetic and mechanistic causes of IS are poorly understood. Here, we focus on PPP2R3B, which encodes a protein phosphatase 2A regulatory subunit. We found that PPP2R3B is expressed at sites of chondrogenesis within human foetuses, including the vertebrae. We also demonstrated prominent expression in myotome and muscle fibres in human foetuses, and zebrafish embryos and adolescents. As there is no rodent orthologue of PPP2R3B, we used CRIPSR/Cas9-mediated gene-editing to generate a series of frameshift mutations in zebrafish ppp2r3b. Adolescent zebrafish that were homozygous for this mutation exhibited a fully penetrant kyphoscoliosis phenotype which became progressively worse over time, mirroring IS in humans. These defects were associated with reduced mineralisation of vertebrae, resembling osteoporosis. Electron microscopy demonstrated abnormal mitochondria adjacent to muscle fibres. In summary, we report a novel zebrafish model of IS and reduced bone mineral density. In future, it will be necessary to delineate the aetiology of these defects in relation to bone, muscle, neuronal and ependymal cilia function