Trigonal cavernous malformation with intraventricular hemorrhage : A case report and literature review

We reported a case of trigonal cavernous malformation (CM) with intraventricular hemorrhage. This 67-year-old woman experienced sudden onset of loss of consciousness and her Glasgow Coma Scale (GCS) was 5 points (E1V1M3) on admission. CT scan demonstrated intraventricular hemorrhage and acute hydrocephalus. Angiography did not demonstrate any vascular abnormality. Ventricular drainage was performed for acute hydrocephalus and the postoperative course was good. CT showed a hyperdense lesion in the left trigone, which was contrast-enhanced on T1-weighted MR. Removal of CM was performed via the left middle temporal sulcus. We conducted a Pub Med search for trigonal CM and found 17 cases. Herein we discuss the symptoms, CT and MR findings and treatment

Optical Properties of 2‑Methacryloyloxyethyl Phosphorylcholine-Protected Au₄ Nanoclusters and Their Fluorescence Sensing of C‑Reactive Protein

We present the solution synthesis of thiolated 2-methacryloyloxyethyl phosphorylcholine (MPC)-protected Au nanoclusters (NCs). This water-soluble lipid-mimetic MPC was first used for the size focusing synthesis of thiolate (SR)-protected Au_<i>n</i>(SR)_<i>m</i> NCs. Au₂₅(MPC)₁₈ and Au₄(MPC)₄ NCs are selectively synthesized, without the need for electrophoretic or chromatographic isolation of size mixed products, by including ethanol or not in the solvent. The Au₄(MPC)₄ NCs emit at yellow wavelengths (580–600 nm) with a quantum yield (3.6%) and an average lifetime of 1.5 μs. Also for the first time, we report C-reactive protein (CRP) sensing using Au NCs, with a detection limit (5 nM) low enough for the clinical diagnosis of inflammation. This is based on the quenching effect of specific CRP–MPC interactions on the fluorescence of the Au₄(MPC)₄ NCs