A research agenda on geoinformation sciences towards responsible land administration in Colombia

After Peace Agreement 2016, new challenges in Land Administration and Land Tenure take relevance in Colombia. This document presents new perspectives on the challenges around land tenure in Colombia. We did three activities a SWOT analysis, a workshop on the research subject, and a literature review about the topics studied by the researchers. As a result, we found the internal and external relationships between Universidad Distrital, different actors, and trends in geoinformation science and land administration. For an efficient and reliable Land Administration System in the mid-term, Colombia needs articulation among different entities responsible for the different parts of the process. In that way, it is necessary to have an infrastructure for implementing multipurpose cadastre, tertiary roads, irrigation, electricity and connectivity, and areas of interest for conservation, which in Colombia are fundamental elements of the peace agreement for the comprehensive rural reform. This way, it is necessary to provide the country with knowledge and information that integrates technical concepts, geospatial technologies, and data sources

Contemporary use of cefazolin for MSSA infective endocarditis: analysis of a national prospective cohort

Objectives: This study aimed to assess the real use of cefazolin for methicillin-susceptible Staphylococcus aureus (MSSA) infective endocarditis (IE) in the Spanish National Endocarditis Database (GAMES) and to compare it with antistaphylococcal penicillin (ASP). Methods: Prospective cohort study with retrospective analysis of a cohort of MSSA IE treated with cloxacillin and/or cefazolin. Outcomes assessed were relapse; intra-hospital, overall, and endocarditis-related mortality; and adverse events. Risk of renal toxicity with each treatment was evaluated separately. Results: We included 631 IE episodes caused by MSSA treated with cloxacillin and/or cefazolin. Antibiotic treatment was cloxacillin, cefazolin, or both in 537 (85%), 57 (9%), and 37 (6%) episodes, respectively. Patients treated with cefazolin had significantly higher rates of comorbidities (median Charlson Index 7, P <0.01) and previous renal failure (57.9%, P <0.01). Patients treated with cloxacillin presented higher rates of septic shock (25%, P = 0.033) and new-onset or worsening renal failure (47.3%, P = 0.024) with significantly higher rates of in-hospital mortality (38.5%, P = 0.017). One-year IE-related mortality and rate of relapses were similar between treatment groups. None of the treatments were identified as risk or protective factors. Conclusion: Our results suggest that cefazolin is a valuable option for the treatment of MSSA IE, without differences in 1-year mortality or relapses compared with cloxacillin, and might be considered equally effective