Method and apparatus for detecting gross leaks Patent

Volume displacement transducer for leak detection in hermetically sealed semiconductor device

Multivariate regression analysis of atmospheric density in the region 30 to 110 km

Multivariate regression analysis of atmospheric density in region 30 to 100 k

Development of Stress Relief Treatments for High Strength Aluminum Alloys Annual Report No. 2, 13 Aug. 1964 - 13 Aug. 1965

Residual stress, strength, and toughness response of high strength aluminum alloys subjected to time-temperature treatment

Navy-developed life support systems for fully enclosed protective suits

The development and performance of an environmental control unit capable of supporting a man in an impermeable suit at ambient temperatures up to 140 F for periods of up to two hrs is reported. The basic suit operation consists of cooling by wet ice contained in a suitcase. The system is designed to circulate and cool the air within the suit, to remove excess moisture and carbon dioxide, and to maintain a safe oxygen level

Kinetic Characterization of Tetracycline Binding and Release by Demineralized Bone - DFDBA

The microbial etiology of periodontal diseases has led to widespread research in the development of methods and local delivery systems to increase the efficacy of antibiotic therapy. Several drug delivery systems employing biodegradable and nonbiodegradable carriers have been shown to release antibiotics directly into periodontal pockets. The purpose of this study was to determine the binding and release kinetics of tetracycline by demineralized bone. Further aspects of the study include in vitro evaluation of DFDBA (demineralized freeze-dried bone allografts) as a tetracycline carrier system for periodontal therapy. Experiments were performed which employed different tetracycline concentrations with constant amounts of bone and constant tetracycline concentrations with different amounts of bone to determine the kinetics of tetracycline binding. Time course studies of tetracycline binding and release by bone were performed to assess binding capacity and release as a function of time. DFDBA was demonstrated to maximally bind 0.014 mg tetracycline per mg dry weight of DFDBA. Thirty percent of the tetracycline bound to DFDBA was released in a time dependent manner over a four hour incubation period. The rate of tetracycline release was curvilinear over the incubation period studied. The rate of release exhibited a rapid linear decrease for the first 40 minutes and followed a very slow and nonlinear decrease over the remaining 200 minutes suggesting DFDBA may act as a slow release device for the tetracycline