2020-05-08 DAILY UNM GLOBAL HEALTH COVID-19 BRIEFING

Executive Summary: UNM drug repurposing. NM cases. Doctors Without Borders. SNAP benefits online. NM 7th highest unemployment. Virtual LemonAid tonight. New N98 masks. Healthcare supply chain challenge. EMS lack resources. Infection risk in healthcare workers. COVID-19 on medical education. Human disinfectant chambers. Evidence of seroconversion. Dangers of considering herd immunity. Wastewater-based surveillance. More youths infected. Reconstructing ship spread. Pharmacoepidemiologic analysis. Clinicopathologic characteristics. Cancer treatment impact. Reduced voluntary psychiatric admission in Italy. Operating room management. Humidifiers reduce transmission. Phone contact tracing ethics. Call for patient database. Immunity certification program. Guidelines on tracheostomy, IBD, nose bleeding, pituitary tumors, and hematopoietic stem cells transplantation, benefits of low-PEEP, and of molecular diagnostics. FDA authorizes at-home test. Cephid Xpert test. MRSA nasal swabs. NIH remdesivir+barictinib RCT. Corticosteroid caution. Arbidol active in vitro. ACE/ARB systematic review. In silico phytochemical and virus protease candidates. Potential zinc benefit. 31 new clinical trials. Glycemic control benefit. Psychological effects meta-analysis and survey. Disease course model. Liver injury. Environmental and health perspectives. Olfactory and gustatory dysfunction. Vitamin D. Disease map

2020-04-24 DAILY UNM GLOBAL HEALTH COVID-19 BRIEFING

Executive Summary: NYT praises NM. NM Governor update. NM cases. NM antibody tests. State hiring freeze. Navajo Nation sues. Navajo Nation CA doctors. Mental health funding. Balloon Fiesta proceeding. Trump Lysol remarks. $484B business relief. 50k US deaths. US no to WHO initiatives. US crime reductions. Moscow 10% infections. Quebec elderly deaths. Italy psychiatric sequelae. Global vaccines summit. French nicotine sales restrictions. Adaptive cyclic exit strategies. Mask reuse techniques. Mask steaming method. Legionnaire’s reopening risks. Youth mental health. US disease models. Covid phobia treatment avoidance. Nursing home testing. Home nursing demand. CDC home cleaning. Guidelines on: convalescent plasma transfusion, H2O2 nasal use, pre-op testing, respiratory distress, ophthalmological practice, GI department reopening. FDA hydroxychloroquine cautions. Chloroquine high-dose mortality. HCQ+azithromycin long-QT. Iron reduction adjuvant. Repurposing prioritization. Pediatric HCQ dosing. HCQ enrollment up. 107 trials registered. PPE skin injuries. LDL and severity. 32 ECMO patients. Worse outcomes older monkeys

2020-05-13 DAILY UNM GLOBAL HEALTH COVID-19 BRIEFING

Executive Summary: APS virtual graduation. NM Governor update. Free testing for all. NM 2020 census challenges. BCBS $1M COVID-19 donation. NM case count. Most tribes infected. Increased NM Medicaid enrollment. UNM revenue losses. UNM limited operations continue. No dine-in eating yet. Clothing store reopening measures. Aid package. Consumer prices tumble. Public guidance adherence survey. Healthcare resource prediction. Food insecurity. Supply system comparison. Pentagon PPE award. Ensemble mortality model. 4.4% French infections. Asymptomatic spread. Traffic infection correlation. Comorbid COPD/smoking mortality. Airplane transmission contained. CDC COVID-19 statistics. WHO: endemic virus risk. Iceland tracking app impact. WHO: prison management. Quality of life. Containment amongst HCWs. Emotional regulation. Literature overload coping. Exercise and well-being. Information sources. Distress among healthcare students. Expanding pharmacy role. Recommendations on sedation in mechanical ventilation. Long-acting antipsychotics usage. Comorbidities and mortality. Continuing clinical trials. Short interval re-testing. Pharynx gargle samples. BCG vaccination not protective. Plasmapheresis case series. Convalescent plasma safety. Neutralizing antibodies. 40 new trials. Acute kidney injury. Multiorgan and renal tropism. Intestinal cell infections. Cardiovascular disease risk link. Cutaneous manifestations. Underpowered studies

2020-05-11 DAILY UNM GLOBAL HEALTH COVID-19 BRIEFING

Executive Summary: NM case counts. Navajo Nation documentary. Medicaid reimbursement increase. Excess NYC mortality. German R0\u3e1. Chile COVID-19 certificates. High female incidence in Quebec. Swab 3D printing. Evidence lacking school reopening. Cloth mask review. WHO 2nd wave warning. Higher mortality in minorities. Environmental transmission controls. Behavior change. Correctional environment guidelines. Wuhan hospital transformation. Maximizing GI training. Threat and conformity. Recommendations on managing COVID-19 (first Italian SARS patients), and obesity and metabolic syndrome. Guidelines for neurologists. Ethics of off-label drugs use. Abbott antibody test approval. CRISPR test FDA approval. Viral sample inactivation. HCQ+azithromycin no benefit. Public-Private partnership for clinical trials. Drug repurposing. Cancer patient considerations. 35 new COVID-19 trials. Hyperinflammatory shock in children. Symptom app

2020-04-30 DAILY UNM GLOBAL HEALTH COVID-19 BRIEFING

Executive Summary: NM residential facility deaths. NM case update. NM TriCore testing antibodies. Navajo nation cases. May 10 Navajo peak. Udall funding push. El Paso shopping discouraged. NM budget shortfall. Santa Fe furlough. Ethanol sanitizer safety. LA free testing for all. Michigan protest. NM Batelle N95 decontamination. Hospital revenue decline. Wastewater early detection. German herd immunity. 60-day viral shedding possible. Temporary infected “ark”. Prison release preparedness. Low quality research. Phased long-term care. Suicide prevention. Corticosteroid tradeoffs. Cloth mask guidelines. SARS-CoV-2 assays compared. IgG and viral loads. Better testing reporting. Dubious testing vendors. Promising oral drug. Hydroxychloroquine prophylaxis dosing. Umifenovir ineffective. Multi-drug nanoparticles. Drug discovery new targets. 38 new COVID-19 trials. Cancer research review. Attenuated SARS-CoV-2

2020-05-05 DAILY UNM GLOBAL HEALTH COVID-19 BRIEFING

Executive Summary: NM cases. Navajo cases. NM remdesivir inaccessible. Infected prison staff. No early prison releases. Unemployment beats working. NM $97M food benefits. UNM$50M revenue loss. Meat packer testing. Fall school reopening planning. Gym/salon reopening plans. 91k absentee ballots. Santa Fe closes polling stations. NM oil/gas pollution oversight. Prisons vulnerable. WH rejects FEMA report. Schools plan reopening. Italian mafia concerns. UK overtakes Italy. Symptom tracker early warning. Ethanol for FFP2 masks. Counterfeit masks. Mask skin damage. Mutant coronavirus more contagious. Hospital contamination zones. Disease prevalence estimation. Successful control measures. Average contagious period. Genetic epidemiology. Managing healthcare resources. Exercise and fitness. Italian disease management Q&A. Practice guidelines on: bronchoscopy, sarcoidosis management, glycemic control, key laboratory tests, ACE/ARB Tx, neurosurgery, cardiac surgery. WHO: test old pneumonia samples. SW NM free testing. Diagnostic assays compared. Corticosteroid benefits. Beekeepers COVID-free? European vaccine US trials. Cytokine storm interventions. Lopinavir-ritonavir second chance. Melatonin potential Tx. 48 clinical trials. Placental infection. Cytokine severity markers. Male lungs worse. Sleep problems. IBD physician survey. Researcher career impact

2020-05-18 DAILY UNM GLOBAL HEALTH COVID-19 BRIEFING

Executive Summary: NM Highlights: NM COVID safety guidelines. NM case count. Navajo Nation case count. Gadsden school district kitchens closures. ABQ non-COVID patient treatment delay. NM factory shutdowns. US Highlights: Moderna Inc. vaccine shows promise. US cases exceed 1.5 million. US states reopen. NY slowly reopening. Michigan vaccines decrease. CDC antibody study. International Highlights: WHO independent review. Economics, Workforce, Supply Chain, PPE Highlights: Maxillofacial surgeries down. PPE skin damage. Epidemiology Highlights: Infections may overwhelm ICE facilities. High estimated US infections. LA antibody testing results. Super-spreader in church. Hospital staff antibody response. No effect of climate. Healthcare Policy Recommendations: Pairing assistance to alleviate health system failure. Exercise recommendations. CDC funeral guidance. Practice Guidelines: Emergency Dept. Patient isolation triage tool. Gynecology ward rearrangement. Guidelines for nuclear cardiology labs. Testing: PCR without RNA extraction. Comparison of PCR kits. Comparison of IgG assays. Sequencing for screening. Drugs, Vaccines, Therapies, Clinical Trials: Subcutaneous tocilizumab. Five new antivirals. 28 new COVID-19 trials. Other Science: PTSD in healthcare workers. Antibody neutralizes virus. Good pregnancy outcomes. Males at risk. CDC: hospitalization and mortality rates. News makes people sad. African green monkey model. Air is cleaner

2020-05-15 DAILY UNM GLOBAL HEALTH COVID-19 BRIEFING

Executive Summary: Governor clarifies health orders. NM childhood deaths high. NM workplace investigations. NM case count. Navajo emergency orders. $77M NM testing/tracing. NM convalescent plasma. NM unemployment claims slow. NM food bank challenges. Farmington Mall protest.$3T bill opposition. Lancet FDA revival call. UK Roche antibody testing. Swedish excess mortality. End of Slovenia pandemic. US invest in COVID-19 vaccine. Safe decontamination N95 respirators. Business occupancy load. 10 years of life lost burden. Forecasting models predict deaths. Infection fatality rate 8%. Resilient medical education. Restrictions: human rights law. Guidelines for nursing homes. Managing hematology and oncology patients. Abbott test accuracy. Lab specimen pooling. Sample self-collection. Improving test accuracy. NIH HCQ+azithromycin RCT. Tocilizumab ineffective -- retrospective study. Aerosolized HCQ. 42 new clinical trials. Smoking link. Cardiovascular disease link. Prone positioning. Alcohol withdrawal. Vitamin D lower

2020-04-21 DAILY UNM GLOBAL HEALTH COVID-19 BRIEFING

Executive Summary: NM updates. YesNM assistance. Ventilator production. Georgia reopening. Wisconsin legal challenge. Pending immigration suspension. Religious restriction parity. Hong Kong restrictions. Global food shortages. Mexico rapid spread. Oil futures negative. Socio-economic implications. Clinical disease patterns. Healthcare worker testing. WHO courses. Vaccine volunteers to be infected. Intervention impacts. Social distancing tribal. NIH releases treatment guidelines. Guidelines on: thromboembolism Tx, IBD endoscopy, vascular surgery, nutritional management, cutaneous lymphomas, cardiac surgery triage, cellular therapy. LA has 40X known cases. At-home testing. ELISA diagnostic tool. CRISPR vs. PCR. Testing coordination. Hydroxychloroquine prophylaxis. VA hydroxychloroquine study. 52 new clinical trials. Coagulation disorders. Cardiac injury. Ansomia features. D-dimer risk. Early warning scores. Artificial intelligence review

2020-04-29 DAILY UNM GLOBAL HEALTH COVID-19 BRIEFING

Executive Summary: NM cases. NM coronavirus origins. Governor update tomorrow. Temporary drivers licenses. Negative tracing app sentiment. CA reopening plans. US travel screening. Influenza reductions w/COVID control. German flu vaccine prep. 1.5B jobs at risk. National health expenditures. US economy shrinks. Aerosolized virus in hospitals. Cellphone disease spread prediction. Social distancing study. Isolation policy effectiveness. Contact tracing to end AIDS/HIV. Homeless shelter prevalence. Predicting herd immunity. Cooler temperatures reduce transmission. NEJM rationing rationalization. ECMO regional planning. Canadian ECMO prioritization. Healthcare worker mental health. Infectious Diseases Society guidelines. US hospitalist guide. Managing pregnancies. Coagulopathy management. Hysteroscopy consensus. Renal transplant immunosuppression. Two RT-PCR alternatives. Remdesivir RCT success. Novaferon promising study. Probiotics evidence summary. Tocilzumab rationale. 53 new clinical trials. Continue ACE use. Coagulopathy risk screening. Liver tests predict progression. Stem-cell organoid model. Phylogenetic network analysis. Severity: innate vs. adaptive immunity. ECMO update