Multinomial logistic regression analysis results for prediction the probabilities of each histological categories given a set of independent variables selected from the logistic regression analysis.

<p>Multinomial logistic regression analysis results for prediction the probabilities of each histological categories given a set of independent variables selected from the logistic regression analysis.</p

Cox regression was use for investigating the effect of histological categories diagnosis upon 15-y death censored graft survival.

<p>Cox regression was use for investigating the effect of histological categories diagnosis upon 15-y death censored graft survival.</p

Multinomial logistic regression analysis was performed to compare the odds ratio for demographic, immunological, clinical and biochemical variables respecting the 5 histological diagnostic groups.

<p>Multinomial logistic regression analysis was performed to compare the odds ratio for demographic, immunological, clinical and biochemical variables respecting the 5 histological diagnostic groups.</p

Frequency of the lesions diagnosed in PB.

<p>Frequency of the lesions diagnosed in PB.</p

Demographic data, kidney function at the time of protocol.

<p>Demographic data, kidney function at the time of protocol.</p

Demographic Table.

<p>*ESRD (1/2/3/4/5/6): 1, glomerulonephritis, 2, polycystic kidney disease, 3, renal dysplasia, 4, reflux nephropathy, 5, obstructive uropathy, 6 = other or unknown. None of these selected patients had delayed graft function. 20% of AR episodes were associated with documentation of non-adherence with medications (self-reported), appointments and/or laboratory measurements. Though the time post-transplant was significantly greater for AR (p<0.05); there was no difference in post-transplant time between no-AR and pIFTA.</p><p>Demographic Table.</p

Graft survival of Banff categories split regarding the presence of inflammation.

<p>In panel A: 15-y graft survival. In panel B: 15-y death-censored graft survival.</p

Impact of inflammation severity on death censored graft survival.

<p>Impact of inflammation severity on death censored graft survival.</p

Individual histological components included in all versions of the Banff classification.

<p>Individual histological components included in all versions of the Banff classification.</p

tCRM score correlates with AR lesions and chronic allograft nephropathy.

<p>[A] The tCRM score positively correlates significantly (p = 0.001) with the degree of infiltrates found on biopsy for the t-score = 0.722 and [B] i score = 0.736. [C] A tCRM score across a subset of 7 of the 11 genes differentiated most samples with pIFTA or progressors (3.29 ± 0.93) from no-AR patients (1.2 ± 0.18; p = 0.037). Stable/non-progressors (NP) and AR were highly distinguishable (1.198±0.1801 versus 5.582±0.8651; p = 0.0063). pIFTA/Progressors and AR were not different with regards to their tCRM scores (p = 0.16).</p