101 research outputs found

    Reconstruction using the lotus petal flap:applications and outcomes

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    This thesis describes the application and outcomes of reconstruction using the lotus petal flap. The lotus petal flap is a fasciocutaneous flap from the groin or infragluteal fold. It can be applied after resection of tumors in the vulvoperineal area. The first study of 93 patients shows that complications occur in about 70% of the patients. Most complications are minor (e.g. wound dehiscence). The quality of life following vulvar reconstruction using the lotus petal flap shows a decrease in quality of life compared to healthy women. However, the quality of life is comparable to patients with vulvar defects which did not need reconstruction with flaps. Sexual functioning is decreased following reconstruction mainly due to pain, but patients are still satisfied with their sexual functioning. The lotus petal flap is known for reconstructions of vulvar defects. It can also be used for reconstruction in the perineal area. The quality of life following perineal reconstruction using the lotus petal flap is comparable to patients with perineal defects which did not need reconstruction with flaps. Sexual activity was clearly decrease following reconstruction using the lotus petal flap, however patients seemed to be satisfied with their sexual functioning. Patients were moderately satisfied with the esthetic outcome. The esthetic outcome scored by patients, laymen and plastic surgeons was comparable

    Analysis of miRNA market trends reveals hotspots of research activity

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    Circular dichroism spectroscopy of heparin-antithrombin interactions

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    Multiple functional domains of the heparin molecule.

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