Characteristics of HIV Patients diagnosed through Screening Program.

∧<p>Medical comorbidities include: hypertension, diabetes, hyperlipidemia, coronary artery disease, depression, gout, benign prostatic hyperplasia, chronic hepatitis B, alcoholic liver disease.</p>∧∧<p>Not indicated to receive antiretroviral therapy based on current WHO HIV treatment guidelines.</p

Comparison of various HIV screening tests conducted in Singapore.

<p>A : January 2007 to December 2007: Action For AIDS (AFA)- Anonymous Testing Site⁶ : [MSM-5.7%, Heterosexual male-0.8%, Heterosexual female- 0.4%].</p><p>B: January 2009 to December 2010.</p><p>TTSH- Routine Voluntary Opt Out Inpatient HIV testing Program (This study).</p><p>C: January 2010 to December 2010 to Antenatal Screening From acute public hospitals and polyclinics (Data from Communicable Disease Division, MOH, Singapore 2010).</p

Data on Total Admissions and Opt Out Voluntary HIV Testing (January 1, 2009 to December 31, 2010).

<p>Data on Total Admissions and Opt Out Voluntary HIV Testing (January 1, 2009 to December 31, 2010).</p

Reasons cited for opting out of HIV Screening Test.

*<p> <b>Other reasons cited include: fear of results, family objected, wants to resolve current medical illness first, deemed low risk.</b></p

Independent predictors of rate of CD4 decline^a.

a<p>Co-variates in the model were subtype, baseline CD4+ T-cell count, baseline log₁₀ viral load and age. Baseline log₁₀ viral load was borderline statistically significant.</p

Cumulative proportion of HIV-1 patients initiating antiretroviral therapy by infecting subtype.

<p>Cumulative proportion of HIV-1 patients initiating antiretroviral therapy by infecting subtype.</p

Characteristics of patients by HIV-1 subtype^a.

a<p>Statistical tests as detailed in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0015738#s2" target="_blank">methods</a> section.</p

Participant interpretation of sample test results, by site.^a

a<p>Five positive samples and 6 invalid were missing interpretation results and excluded from analysis.</p>b<p>P-value comparing incorrect interpretation between known HIV-positive participants and others was <0.001.</p>c<p>P-value comparing incorrect interpretation between known HIV-positive participants and others was 0.023.</p

Selected participants’ opinions regarding self-testing before and after self-testing, by site.^a

a<p>Missing data, which accounted for less than 2% of participants for any question, was omitted from analysis.</p

Pattern of self-test results, by healthcare worker testing results.^a

a<p>Three invalid self-tests were excluded from analysis, of which 1 was paired with a positive healthcare worker test and another 2 paired with a negative healthcare worker test. Eight result pairs with missing data were also excluded from analysis.</p