Successful treatment of severe carbimazole induced agranulocytosis by lithium carbonate

Singapore Medical Journal194225-226SIMJ

HLA antigen in Chinese patients with hepatocellular carcinomas

Journal of the National Cancer Institute65121-23JNCI

Hepatocellular carcinoma in a patient on oral contraception who had been exposed to hepatitis B virus

Lancet28135194-195LANC

Immunocytochemical localization of testosterone in human hepatocellular carcinoma

Histochemical Journal166687-692HISJ

Prick skin tests in bronchial asthma and their correlation with the specific serum IgE levels

Singapore Medical Journal184228-231SIMJ

New concepts on the acute leukaemias: morphology, classification, cell biology, chemotherapy, supportive care, immunotherapy and bone marrow transplantation

Annals of the Academy of Medicine Singapore103353-363AAMS

Independent emergence of a vaccine-induced escape mutant of hepatitis B virus

We investigated the case of a child who was vaccinated at birth against hepatitis B and was also given hepatitis B immune globulin, but who nevertheless later became infected with the virus. Hepatitis B virus-specific deoxyribonucleic acid covering the region of the genome encoding the predominant a epitope of hepatitis B surface antigen was amplified using the polymerase chain reaction and the nucleotide sequence determined. We present evidence for the independent emergence of an escape mutant, similar to that previously identified in Italy, where a substitution of arginine for glycine has occurred in the second loop of the a epitope

Evidence of viral replication in HBsAg positive patients with hepatocellular carcinoma: measurement of serum hepatitis B virus deoxyribonucleic acid (HBV-DNA).

Annals of the Academy of Medicine Singapore1818-1

Primary hepatocellular carcinoma developing in a female patient on long term oral contraceptives - a case report

Annals of the Academy of Medicine Singapore93402-404AAMS