Prognosis analysis according to the predominant histological pattern in cases with lung adenocarcinoma undergoing complete resection

Lung adenocarcinoma accounts for over 40% of lung cancer cases. There is still uncertainty in terms of prognosis, particularly because of limited pathological information among the predominant sub-patterns of adenocarcinomas. In this study, we evaluated the prognostic relationship with the predominant histological patterns in adenocarcinoma cases that underwent complete resection in one year. We retrospectively evaluated 100 patients with lung adenocarcinoma, whose pathological stage was determined after complete resection. Six patients were excluded from the study because of missing data in their files. The mortality rates and tumor stages of the patients were analyzed according to their histopathological subtypes with the predominant pattern. Seventy-four (79%) of the cases were male and 20 (21%) were female. The predominant pattern was solid in 41 (43.6%) patients, acinar in 31 (33%) patients, papillary in 10 (10.6%) patients, lepidic in 9 (9.6%) patients and micropapillary in 3 (3.2%) patients. Lymph node involvement was N0 in 30 (73.2%) patients, N1 in 9 (22%) patients and N2 in 2 (4.9%) patients in the solid group; N0 in 22 (71%) patients, N1 in 3 (9.7%) patients, and N2 in 6 (19.4%) patients in the acinar group. In the solid group, 23 (56.1%) patients survived, and 18 (14.6%) patients died, whereas 21 (67.7%) patients survived, and 10 (32.2%) patients died in the acinar group. The mean follow-up period of the patients was 32 months. In the mean follow-up of all patients, 58 (61.7%) survived and 36 (38.3%) died. No significant difference was observed between the subtypes in terms of mortality (p>0.05). N2 involvement was higher in acinar adenocarcinomas compared with the solid pattern, and the advanced stage due to the T factor was observed more in the solid pattern. Acinar-type adenocarcinoma shows similar prognostic characteristics to those with the solid pattern. [Med-Science 2022; 11(2.000): 581-5

Sol Pnömotoraks ile Santral Kitle Pnömonektomi Sonrası Kontralateral Pnömotoraks

Pnömonektomi sonrası pnömotoraks gelişmesi morbidite ve mortalitesi yüksek bir durum olup ender seyreder. Sol ana bronşta kitlesi bulunan olgumuzda fiberoptik bronkoskopi (FOB) sonrası iyatrojenik pnömotoraks gelişti, vitalleri stabil olduğu için tüp torakostomi uygulanmadı. Aynı seansta mediastinoskopi ve pnömonektomi uygulandı. Bu çalışmada, postoperatif erken dönemde kontralateral pnömotoraks gelişen olgu literatür eşliğinde sunulmaktadır