14 research outputs found
Plots of PAH isomer pair ratios for source identification (Ant/(Ant+Phy) vs Flu/(Flu+Pyr).
<p>Plots of PAH isomer pair ratios for source identification (Ant/(Ant+Phy) vs Flu/(Flu+Pyr).</p
Location of the sampling stations in Klang Strait.
<p>Location of the sampling stations in Klang Strait.</p
Concentration of PAHs (µg/kg dw) in surface sediments of Klang Strait.
<p>TELs (threshold effects level) and PELs (probable effects level), ** </p
Cluster analyses to classify stations based on adverse biological effect of PAHs in surface sediment.
<p>Cluster analyses to classify stations based on adverse biological effect of PAHs in surface sediment.</p
Molecular indices of PAHs, content in surface sediments of Klang Strait.
<p><b>∑ PAH </b><b><i><sub>combust</sub></i></b>: Combustion value of PAHs calculated as sum of concentration of high-molecular-weight PAHs include Fla, Pyr, BaA, Chy, BbF, BkF, BaP, InP, DibA, BghiP; <b>∑ PAH </b><b><i><sub>toxic</sub></i></b>: Toxic value of PAHs calculated as sum of concentration of BaA, Chy, BbF, BkF, BaP, InP and DibA; L/H: ratio of low molecular weight hydrocarbon (<b>n</b>-C10–<b>n</b>-C14) to high molecular weight hydrocarbon (<b>n</b>-C16–<b>n</b>-C22).</p
Rotated component matrix of 16 PAHs from the Klang Strait sediment.
<p>*Rotation method: Varimax with Kaiser normalization.</p><p>*Bold loadings >0.70.</p
Spatial variations of PAHs compounds in surface sediment of the Klang Strait (a: Total PAHs, b: PAHs <sub>combust</sub>, c: PAHs <sub>toxic</sub>).
<p>Spatial variations of PAHs compounds in surface sediment of the Klang Strait (a: Total PAHs, b: PAHs <sub>combust</sub>, c: PAHs <sub>toxic</sub>).</p
Data_Sheet_2_Overlapping Distribution of Orexin and Endocannabinoid Receptors and Their Functional Interaction in the Brain of Adult Zebrafish.docx
<p>Hypocretins/Orexins neuropeptides are known to regulate numerous physiological functions, such as energy homeostasis, food intake, sleep/wake cycle, arousal and wakefulness, in vertebrates. Previous studies on mice have revealed an intriguing orexins/endocannabinoids (ECs) signaling interaction at both structural and functional levels, with OX-A behaving as a strong enhancer of 2-arachydonoyl-glycerol (2-AG) biosynthesis. In this study, we describe, for the first time in the brain of zebrafish, the anatomical distribution and co-expression of orexin (OX-2R) and endocannabinoid (CB1R) receptors, suggesting a functional interaction. The immunohistochemical colocalization of these receptors by confocal imaging in the dorsal and ventral telencephalon, suprachiasmatic nucleus (SC), thalamus, hypothalamus, preoptic area (PO) and cerebellum, is reported. Moreover, biochemical quantification of 2-AG levels by LC-MS supports the occurrence of OX-A-induced 2-AG biosynthesis in the zebrafish brain after 3 h of OX-A intraperitoneal (i.p.; 3 pmol/g) or intracerebroventricular (i.c.v.; 0.3 pmol/g) injection. This effect is likely mediated by OX-2R as it is counteracted by i.p./i.c.v administration of OX-2R antagonist (SB334867, 10 pmol/g). This study provides compelling morphological and functional evidence of an OX-2R/CB1R signaling interaction in the brain of adult zebrafish, suggesting the use of this well-established vertebrate animal model for the study of complex and phylogenetically conserved physiological functions.</p
<i>Varicella zoster</i> age specific seroprevalence in Iranian adolescents: the CASPIAN-III Study.
<p><i>Varicella zoster</i> age specific seroprevalence in Iranian adolescents: the CASPIAN-III Study.</p
Individual-and provincial-level characteristics of studied population by regions: the CASPIAN-III Study.
<p>Individual-and provincial-level characteristics of studied population by regions: the CASPIAN-III Study.</p