6 research outputs found

    Additional file 4: of Identification of a blood-borne miRNA signature of synovial sarcoma

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    Illustration of the miRNA-expression levels of the two active synovial sarcoma patients who received chemotherapy (Patient 2 and 3 of the screening cohort of active synovial sarcoma patients as depicted in Additional file 3 ) marked with a triangle, patients receiving anticoagulation (Patient 3 of the screening cohort of active synovial sarcoma patients and Patient 1 of the independent cohort of active synovial sarcoma patients as depicted in Additional file 3 ) marked in green and patients receiving radiotherapy/presenting localized disease (Patient 1 of the screening cohort of active synovial sarcoma patients as depicted in Additional file 3 ) marked in red. A, C, E, G, I, K and M include the screening cohort of active synovial sarcoma patients, B, D, F, H, J, L and N depict the independent cohort (IC) of synovial sarcoma patients. (JPEG 5044 kb

    Additional file 1: of Identification of a blood-borne miRNA signature of synovial sarcoma

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    Demographic patient data and blood count of patients with active sarcoma and control groups. Demographic patient data (age, BMI) and blood count (hemoglobin level, platelet count and leukocyte count) of patients with active synovial sarcoma compared to healthy donors, patients with synovial sarcoma in remission and patients with active leiomyosarcoma, MPNST, Ewing sarcoma and liposarcoma. Data are presented as mean value ± standard error of mean (SEM). p- values were determined using a Student’s t-test for independent samples. Hb = Hemoglobin. BMI = Body Mass Index. (PPTX 68 kb

    Additional file 5: of Identification of a blood-borne miRNA signature of synovial sarcoma

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    Comparison of whole blood miRNA expression levels of patients with active synovial sarcoma and miRNA expression levels of corresponding synovial sarcoma tissue. MiRNA-expression of patients with synovial sarcoma expressing SS18-SSX2 are marked in purple. A. miR-99a-5p. B. miR-146b-5p. C. miR-148b-3p. D. miR-195-5p. E. miR-223-3p. F. miR-500b-3p. G. miR-505-3p. (JPEG 2837 kb

    Additional file 2: of Identification of a blood-borne miRNA signature of synovial sarcoma

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    Demographic patient data and blood count of patients with active sarcoma (Individual Cohort (IC)) and control groups. Demographic patient data (age, BMI) and blood count (hemoglobin level, platelet count and leukocyte count) of patients with active synovial sarcoma (Individual Cohort (IC)) compared to healthy donors and patients with synovial sarcoma in remission. Data are presented as mean value ± standard error of mean (SEM). p- values were determined using a Student’s t-test for independent samples. Hb = Hemoglobin. BMI = Body Mass Index. IC = Independent Cohort. (PPTX 66 kb

    Additional file 3: of Identification of a blood-borne miRNA signature of synovial sarcoma

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    Disease and therapy status of sarcoma patients. M0 = localized disease. M1 = metastatic disease. Current chemotherapy/radiotherapy involves treatment within the last 6 weeks. (PPTX 67 kb
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