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The importance of including habitat-specific behaviour in models of butterfly movement
Dispersal is a key process affecting population persistence and major factors affecting dispersal rates are the amounts, connectedness and properties of habitats in landscapes. We present new data on the butterfly Maniola jurtina in flower-rich and flower-poor habitats that demonstrates how movement and behaviour differ between sexes and habitat types, and how this effects consequent dispersal rates. Females had higher flight speeds than males but their total time in flight was four times less. The effect of habitat type was strong for both sexes, flight speeds were ~2.5x and ~1.7x faster on resource-poor habitats for males and females respectively, and flights were approximately 50% longer. With few exceptions females oviposited in the mown grass habitat, likely because growing grass offers better food for emerging caterpillars, but they foraged in the resource-rich habitat. It seems that females faced a trade-off between ovipositing without foraging in the mown grass or foraging without ovipositing where flowers were abundant. We show that taking account of habitat-dependent differences in activity, here categorised as flight or non-flight, is crucial to obtaining good fits of an individual-based model to observed movement. An important implication of this finding is that incorporating habitat-specific activity budgets is likely necessary for predicting longer-term dispersal in heterogeneous habitats as habitat-specific behaviour substantially influences the mean (>30% difference) and kurtosis (1.4x difference) of dispersal kernels. The presented IBMs provide a simple method to explicitly incorporate known activity and movement rates when predicting dispersal in changing and heterogeneous landscapes
Semiclassical states for quantum cosmology
In a metric variable based Hamiltonian quantization, we give a prescription
for constructing semiclassical matter-geometry states for homogeneous and
isotropic cosmological models. These "collective" states arise as infinite
linear combinations of fundamental excitations in an unconventional "polymer"
quantization. They satisfy a number of properties characteristic of
semiclassicality, such as peaking on classical phase space configurations. We
describe how these states can be used to determine quantum corrections to the
classical evolution equations, and to compute the initial state of the universe
by a backward time evolution.Comment: 13 page
Crystal structure of the catalytic fragment of murine poly(ADP-ribose) polymerase-2.
Poly(ADP-ribose) polymerase-1 (PARP-1) has become an important pharmacological target in the treatment of cancer due to its cellular role as a 'DNA-strand break sensor', which leads in part to resistance to some existing chemo- and radiological treatments. Inhibitors have now been developed which prevent PARP-1 from synthesizing poly(ADP-ribose) in response to DNA-breaks and potentiate the cytotoxicity of DNA damaging agents. However, with the recent discoveries of PARP-2, which has a similar DNA-damage dependent catalytic activity, and additional members containing the 'PARP catalytic' signature, the isoform selectivity and resultant pharmacological effects of existing inhibitors are brought into question. We present here the crystal structure of the catalytic fragment of murine PARP-2, at 2.8 A resolution, and compare this to the catalytic fragment of PARP-1, with an emphasis on providing a possible framework for rational drug design in order to develop future isoform-specific inhibitors
A 'moment-conserving' reformulation of GW theory
We show how to construct an effective Hamiltonian whose dimension scales
linearly with system size, and whose eigenvalues systematically approximate the
excitation energies of theory. This is achieved by rigorously expanding
the self-energy in order to exactly conserve a desired number of
frequency-independent moments of the self-energy dynamics. Recasting in
this way admits a low-scaling approach to build this
Hamiltonian, with a proposal to reduce this further to . This
relies on exposing a novel recursive framework for the density response moments
of the random phase approximation (RPA), where the efficient calculation of its
starting point mirrors the low-scaling approaches to compute RPA correlation
energies. The frequency integration of which distinguishes so many
different variants can be performed directly and cheaply in this moment
representation. Furthermore, the solution to the Dyson equation can be
performed exactly, avoiding analytic continuation, diagonal approximations or
iterative solutions to the quasiparticle equation, with the full-frequency
spectrum of all solutions obtained in a complete diagonalization of this
effective static Hamiltonian. We show how this approach converges rapidly with
respect to the order of the conserved self-energy moments, and is applied
across the benchmark dataset to obtain accurate spectra in
comparison to traditional implementations. We also show the ability to
systematically converge all-electron full-frequency spectra and high-energy
features beyond frontier excitations, as well as avoiding discontinuities in
the spectrum which afflict many other approaches
The motivating operation and negatively reinforced problem behavior. A systematic review.
The concept of motivational operations exerts an increasing influence on the understanding and assessment of problem behavior in people with intellectual and developmental disability. In this systematic review of 59 methodologically robust studies of the influence of motivational operations in negative reinforcement paradigms in this population, we identify themes related to situational and biological variables that have implications for assessment, intervention, and further research. There is now good evidence that motivational operations of differing origins influence negatively reinforced problem behavior, and that these might be subject to manipulation to facilitate favorable outcomes. There is also good evidence that some biological variables warrant consideration in assessment procedures as they predispose the person's behavior to be influenced by specific motivational operations. The implications for assessment and intervention are made explicit with reference to variables that are open to manipulation or that require further research and conceptualization within causal models
Recent occurrence of Cylindrospermopsis raciborskii, in Waikato lakes of New Zealand.
Cylindrospermopsis raciborskii is a toxin-producing species of cyanobacteria that in autumn 2003 was recorded for the first time in three shallow (max. depth ≤5 m) Waikato lakes and a hydro-electric dam on the Waikato River, New Zealand. It formed water blooms at densities >100 000 cells/ml in Lakes Waahi and Whangape. Net rates of population growth >0.2 day-1 were recorded for C. raciborskii in Lakes Ngaroto, Waahi, and Karapiro, based on comparisons of low numbers (detection of cells/ml) from initial samples and its presence at bloom densities (>15 000 cells/ml) in the subsequent sample "x"-"y" days later. C. raciborskii may be well adapted to rapid proliferation in the Waikato lakes, which are eutrophic to hypertrophic, with high light attenuation, and where nitrogen (N) fixation may provide it with a competitive advantage over non-nitrogen fixing algae under N-limited conditions
Temporary vascular shunting in vascular trauma: A 10-year review from a civilian trauma centre
BACKGROUND: Temporary intravascular shunts (TIVSs) can replace immediate definitive repair as a damage control procedure in vascular trauma. We evaluated their use in an urban trauma centre with a high incidence of penetrating trauma. METHOD: A retrospective chart review of all patients treated with a TIVS in a single centre between January 2000 and December 2009. RESULTS: Thirty-five TIVSs were placed during the study period: 22 were part of a damage control procedure, 7 were inserted at a peripheral hospital without vascular surgical expertise prior to transfer, and 6 were used during fixation of a lower limb fracture with an associated vascular injury. There were 7 amputations and 5 deaths, 4 of the TIVSs thrombosed, and a further 3 dislodged or migrated. Twenty-five patients underwent definitive repair with an interposition graft, 1 primary anastomosis was achieved, and 1 extra-anatomical bypass was performed. Five patients with non-viable limbs had the vessel ligated. CONCLUSIONS: A TIVS in the damage control setting is both life- and limb-saving. These shunts can be inserted safely in a facility without access to a surgeon with vascular surgery experience if there is uncontrollable bleeding or the delay to definitive vascular surgery is likely to be more than 6 hours. A definitive procedure should be performed within 24 hours
Oscillatory Modes of a Prominence-PCTR-Corona Slab Model
Oscillations of magnetic structures in the solar corona have often been
interpreted in terms of magnetohydrodynamic waves. We study the adiabatic
magnetoacoustic modes of a prominence plasma slab with a uniform longitudinal
magnetic field, surrounded by a prominence-corona transition region (PCTR) and
a coronal medium. Considering linear small-amplitude oscillations, the
dispersion relation for the magnetoacoustic slow and fast modes is deduced
assuming evanescent-like perturbations in the coronal medium. In the system
without PCTR, a classification of the oscillatory modes according to the
polarisation of their eigenfunctions is made in order to distinguish modes with
fast-like or slow-like properties. Internal and external slow modes are
governed by the prominence and coronal properties respectively, and fast modes
are mostly dominated by prominence conditions for the observed wavelengths. In
addition, the inclusion of an isothermal PCTR does not substantially influence
the mode frequencies, but new solutions (PCTR slow modes) are present.Comment: Accepted for publication in Solar Physic
Thermodynamic formalism for the Lorentz gas with open boundaries in dimensions
A Lorentz gas may be defined as a system of fixed dispersing scatterers, with
a single light particle moving among these and making specular collisions on
encounters with the scatterers. For a dilute Lorentz gas with open boundaries
in dimensions we relate the thermodynamic formalism to a random flight
problem. Using this representation we analytically calculate the central
quantity within this formalism, the topological pressure, as a function of
system size and a temperature-like parameter \ba. The topological pressure is
given as the sum of the topological pressure for the closed system and a
diffusion term with a \ba-dependent diffusion coefficient. From the
topological pressure we obtain the Kolmogorov-Sinai entropy on the repeller,
the topological entropy, and the partial information dimension.Comment: 7 pages, 5 figure
Testing Bell's inequality with two-level atoms via population spectroscopy
We propose a feasible experimental scheme, employing methods of population
spectroscopy with two-level atoms, for a test of Bell's inequality for massive
particles. The correlation function measured in this scheme is the joint atomic
function. An inequality imposed by local realism is violated by any
entangled state of a pair of atoms.Comment: 4 pages, REVTeX, no figures. More info on
http://www.ligo.caltech.edu/~cbrif/science.htm
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