7,976 research outputs found
Birkhoff's Theorem in Higher Derivative Theories of Gravity
In this paper we present a class of higher derivative theories of gravity
which admit Birkhoff's theorem. In particular, we explicitly show that in this
class of theories, although generically the field equations are of fourth
order, under spherical (plane or hyperbolic) symmetry, all the field equations
reduce to second order and have exactly the same or similar structure to those
of Lovelock theories, depending on the spacetime dimensions and the order of
the Lagrangian.Comment: 7 pages, no figures. v1: This version received an Honorable Mention
from the Gravity Research Foundation - 2011 Awards for Essays on Gravitation.
v2: Expanded version. To appear in CQ
The TNG Near Infrared Camera Spectrometer
NICS (acronym for Near Infrared Camera Spectrometer) is the near-infrared
cooled camera-spectrometer that has been developed by the Arcetri Infrared
Group at the Arcetri Astrophysical Observatory, in collaboration with the
CAISMI-CNR for the TNG (the Italian National Telescope Galileo at La Palma,
Canary Islands, Spain).
As NICS is in its scientific commissioning phase, we report its observing
capabilities in the near-infrared bands at the TNG, along with the measured
performance and the limiting magnitudes. We also describe some technical
details of the project, such as cryogenics, mechanics, and the system which
executes data acquisition and control, along with the related software.Comment: 7 pages, 5 figures, compiled with A&A macros. A&A in pres
A new formulation of oral viscous budesonide in treating of paediatric eosinophilic oesophagitis: a pilot study
OBJECTIVES:
Oral viscous budesonide is a recent therapeutic option for eosinophilic oesophagitis (EoE) compared with dietary restriction and inhaled steroids. This single-centre, open-label, not blinded study aims to evaluate the efficacy and safety of a new, preprepared oral viscous budesonide suspension (PVB) in children and adolescents with EoE.
METHODS:
We treated 36 children with PVB (29 boys; median age 12 years) with EoE diagnosed according to European Society for Paediatric Gastroenterology Hepatology and Nutrition guidelines. Patients <150 and >150 cm height received 2 and 4 mg PVB daily, respectively, for 12 weeks. Upper gastrointestinal endoscopy was performed at baseline, after 12 weeks of therapy and 24 weeks after the end of therapy. Baseline and post-treatment scores were calculated for symptoms, endoscopy, and histology. Serum cortisol was performed at baseline, 12, and 36 weeks.
RESULTS:
At the end of PVB trial, endoscopy showed macroscopic remission in 32 patients (88.9%), whereas at histology median pre- and post-treatment peak eosinophil count/high power field (HPF) markedly decreased from 42.2 (range: 15-100) to 2.9 (range: 0-30); moreover, mean symptom and histology scores impressively improved compared with baseline (P < 0.01). At 24 weeks after the end of PVB therapy, endoscopy showed oesophageal relapse in 21 patients (58.3%), whereas 15 (41.7%) were still in remission. Seven children (19.4%) with positive multichannel intraluminal impedance-pH were treated also with proton pump inhibitors. No significant difference between pre-/post-treatment morning cortisol levels occurred.
CONCLUSIONS:
The new PVB suspension presented in the present study is effective and safe for treating children with proven EoE. Larger placebo-controlled clinical trials would provide more information about dosing, efficacy, and long-term safety of this formulation, specifically designed for the oesophagus
Analysis and design of a drain water heat recovery storage unit based on PCM plates
© 2016. This version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/This paper is focused on the detailed analysis of a PCM plate heat storage unit with a particular configuration, looking for the maximum contact area with the fluid (water) and the minimum volume to be used in a real household application. In that sense, a numerical study of the thermal and fluid dynamic behaviour of the water flow and the PCM melting-solidification processes, together with the thermal behaviour of the solid elements of the unit, has been carried out. On the other hand, an experimental set-up has been designed and built to validate the numerical model and characterise the performance of the heat storage unit. The purpose of the numerical and experimental study is to present a series of results to describe the heat storage unit performance in function of the time. Thus, after a preliminary design study three different cases have been simulated and tested. A 7.2% of discrepancy between numerical results and experimental data has been evaluated for the heat transfer. The PCM heat storage unit designed is capable to store approx. 75% of the thermal energy from the previous process wasted water heat, and recover part of it to supply around 50% of the thermal energy required to heat up the next process.Peer ReviewedPostprint (author's final draft
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