UPGMA dendrogram based on PFGE pattern of 26 <i>K. pneumoniae</i> isolates and their sequence type.

<p>Percentage of similarities is indicated in the branches of the dendrogram.</p

Molecular characteristics of KPC-producing clinical isolates in Ontario, 2008/2011 (N = 30).

a<p>Kpn, <i>Klebsiella pneumoniae</i>; Ror, <i>Raoultella ornithinolytica</i>; Ecl, <i>Enterobacter cloacae</i>; Cfr, <i>Citrobacter freundii</i>.</p>b<p>Number of bands detected in the S1-PFGE gels, representing one plasmid each.</p>c<p>Clinical isolates were negative for all the 18 plasmid replicons tested using Carattoli et al approach <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0116421#pone.0116421-Carattoli1" target="_blank">[20]</a> and their plasmids were defined as untypeable.</p><p>Molecular characteristics of KPC-producing clinical isolates in Ontario, 2008/2011 (N = 30).</p

Susceptibility profiles of KPC-producing clinical isolates (N = 30).

a<p>Susceptibility categories were defined according to CLSI breakpoints <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0116421#pone.0116421-Clinical1" target="_blank">[14]</a> except for colistin and tigecycline (EUCAST breakpoints; colistin: S, ≤2 µg/ml; R, >2 µg/ml; tigecycline: S, ≤1 µg/ml; R, >2 µg/ml).</p><p>Susceptibility profiles of KPC-producing clinical isolates (N = 30).</p