Role and Place of Institutional Capacity in Socio-Economic Development

Purpose: The purpose of the study is to substantiate the place and role of institutional capacity in socio-economic development (SED), taking into account the regional context.   Theoretical framework: To conduct the study, it was highlighted that the SED of society and the state is a process, as a result of which new opportunities are created for the subjects of public relations in obtaining income from the use of the potential of the resource base in the field of rental relations. The effectiveness of such a process is directly related to the process of managing the development of economic potential, which determines its role and place in the SED of society and the state.   Design/methodology/approach: In the study, the following components are classified as structural elements of economic potential: resource and institutional potential. To clarify the methodological approach to assessing the institutional potential of SED, as a category of social relations, the terminological basis of this concept was considered. Institutional potential, as a scientific concept that expresses the development of the most general institutional ties in socially significant relations between subjects of public relations, is studied in the system of socio-economic transformation "resource-potential-capital", in which the institution is a resource. The place of institutional potential is determined by the direction of evolutionary changes in SED aimed at meeting the diverse needs of society. At the same time, the institutional transformation of its resource potential creates opportunities for the subjects of this process to receive income in various areas of social relations.   Findings: As a result of the study of the role of institutional capacity, a scientific rationale was obtained for managing the effectiveness of SED, which is associated with the result of its development. As a result of the process of transformation of institutional potential, it is an institutional rent, that is, the possibility of extracting monopoly income by the subjects of rent relations in the SED process.   Research, Practical & Social implications: The study of the terminological basis of the concept of "institutional potential", as a category of SED, allows us to expand the methodology of exploratory and fundamental research in the field of the influence of institutions on the evolution of social relations in relation to the problems of managing the processes of development of a competitive environment.   Originality/value: Clarification of the institutional potential concept, as well as substantiation of its role and place in the assessment and implementation of SED processes, allows us to propose mechanisms for adjusting institutions operating in society in order to increase the effectiveness of the SED institutional model

Diagnostics of Regions Resource Potential in the Context of Socio-Economic Development

Purpose: The purpose of the study is to study the possibilities for diagnosing the resource potential of the regions, taking into account the indicators of their socio-economic development.   Theoretical framework: To conduct the study, the indicators characterizing the socio-economic development of the regions were analyzed; Based on the selected indicators, indices of sub-potentials and integral estimates of the resource potential of the regions were calculated.   Design/methodology/approach: The diagnostics of the resource potential of the regions is carried out by means of an integral assessment of sub-potentials through an indicative analysis, where the average values for the country are the standard. The obtained indicative estimates (indices) for the sub-potentials of the resource potential make it possible to identify rent-forming conditions in the regions. It is proposed to use a “simplified” diagnostic model for the study, which contains the main indicators for analysis; in the "enlarged" model, it is planned to use an expanded range of indicators to identify dependencies, taking into account their dynamic changes. Approbation was carried out in the Russian region - Novgorod region.   Findings: As a result of the study, indicative estimates (indices) of the subpotentials of the resource potential of the analyzed regions were obtained, and their integral estimates of the resource potential were determined. The diagnostics of the resource potential made it possible to rank the regions according to the factor conditions of socio-economic development, as well as to lay the basis for assessing the effectiveness of the use of regional resource opportunities.   Research, Practical & Social implications: The study expands scientific knowledge in the field of formation and use of the resource potential of the regions. Improving the assessment system within the proposed approach for conducting diagnostics for specific regional tasks will allow for a competent regional policy with a focus on the strengths and weaknesses of the socio-economic development of the region.   Originality/value: The value of the study lies in the ranking of regions depending on resource conditions, which can help determine rent-forming factors and build an assessment of the efficiency of using resource potential

Possibilities for creating Russian high-tech bottomhole assembly

Development of high-tech well electronic measuring systems is aimed at creating modern equipment: telemetry, well geophysical measurement equipment, the architecture of which is divided into basic (with measurement channels for gamma logging and inductive resistance) and advanced (with radioactive, acoustic, magnetic resonance and thermobarometric measurement channels, including azimuthal methods of investigation). Over-the-bit measurement modules, rotary steerable systems are being developed and channels for transmitting data to the surface are being improved. Vice versa, specialized surface equipment with highly integrated software is being created. Different measurement modules are manufactured by different companies, which creates uncertainties in the possibility of interfacing the manufacturers' measurement modules into a single well measurement system. The article presents an analysis of the readiness of Russian oil service companies to produce well and surface equipment for drilling Russian directional oil and gas wells, meeting modern requirements for accuracy, lifetime and operating conditions. The possibility of creating a fully Russian well high-tech equipment and the required resources, risks and measures to mitigate them when creating a modern well measurement system are considered

Helicobacter pylori Diagnostic Tests Used in Europe : Results of over 34,000 Patients from the European Registry on Helicobacter pylori Management

Funding Information: This study was funded by Richen; however, clinical data were not accessible and the company was not involved in any stage of the Hp-EuReg study (design, data collection, statistical analysis, or manuscript writing). We want to thank Richen for their support. This project was promoted and funded by the European Helicobacter and Microbiota Study Group (EHMSG), the Spanish Association of Gastroenterology (AEG) and the Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd). The Hp-EuReg was co-funded by the European Union programme HORIZON (grant agreement number 101095359) and supported by the UK Research and Innovation (grant agreement number 10058099). The Hp-EuReg was co-funded by the European Union programme EU4Health (grant agreement number 101101252). Acknowledgments We want to especially thank Sylva-Astrik Torossian for her assistance in language editing. Natalia García Morales is the first author who is acting as the submission’s guarantor. All authors approved the final version of the manuscript.Peer reviewedPublisher PD

Effectiveness of empirical <i>Helicobacter pylori</i> eradication therapy with furazolidone in Russia: results from the European Registry on <i>Helicobacter pylori</i> Management (Hp-EuReg)

Background. First-line therapy does not always provide a high level of Helicobacter pylori eradication due to the increase of H. pylori resistance to antibiotics; therefore, it remains necessary to identify the most effective rescue treatments. The purpose of this study was to evaluate the efficacy and safety of empirical H. pylori furazolidone-containing regimens. Materials and methods. Adult H. pylori infected patients empirically treated with furazolidone-containing eradication regimens were registered in an international, prospective, multicenter non-intervention European registry on H. pylori management (Hp-EuReg). Data were collected at AEG-REDCap e-CRF from 2013 to 2021 and the quality was reviewed. Modified intention-to-treat (mITT) effectiveness analyses were performed. Results. Overall 106 patients received empirical furazolidone-containing therapy in Russia. Furazolidone was prescribed in a sequential scheme along with amoxicillin, clarithromycin and a proton pump inhibitor in 68 (64%) cases, triple regimens were prescribed in 28 (26%) patients and quadruple regimens in 10 (9.4%). Treatment duration of 7 days was assigned to 2 (1.9%) patients, 10-day eradication therapy in case of 80 (75%) and 14 days in 24 (23%) patients. Furazolidone was mainly used in first- (79%) and second-line (21%) regimens. The methods used to diagnose H. pylori infection were: histology (81%), stool antigen test (64%), 13C-urea breath test (6.6%), and rapid urease test (1.9%). The mITT effectiveness of sequential therapy was 100%; 93% with the triple therapy and 75.5% with quadruple therapy. Compliance was reported in 98% of cases. Adverse events were revealed in 5.7% of patients, mostly nausea (3.8%). No serious adverse events were reported. Conclusion. Furazolidone containing eradication regimens appear to be an effective and safe empirical therapy in Russia

On closure of the pre-images of families of mappings

summary:The closures of the pre-images associated with families of mappings in different topologies of normed spaces are considered. The question of finding a description of these closures by means of families of the same kind as original ones is studied. It is shown that for the case of the weak topology this question may be reduced to finding an appropriate closure of a given family. There are discussed various situations when the description may be obtained for the case of the strong topology. An example of a family is constructed which shows that it is, in general, impossible to find such a description for this case