Boxplot of the number of CD34-stained vessels/mm² in preatheromas (AHA III) and advanced atheromas (AHA IV-VI).

<p>Boxplot of the number of CD34-stained vessels/mm² in preatheromas (AHA III) and advanced atheromas (AHA IV-VI).</p

Histological plaque features and immunostaining in upstream and downstream regions.

<p>Histological plaque features and immunostaining in upstream and downstream regions.</p

Increased Vascularization in the Vulnerable Upstream Regions of Both Early and Advanced Human Carotid Atherosclerosis - Fig 1

<p>CEUS image of the carotid artery (A) with a plaque in the near wall. The plaque border is marked with orange and the upstream/downstream divider as a purple line (lines have been enhanced for clarification). B: CQP image with the mean pixel intensity. Automatically excluded areas marked green. C: CQP image with pixels with mean intensity above threshold level marked white.</p

Patient characteristics.

<p>Patient characteristics.</p

Example of immunostaining of different antibodies.

<p>A: Overview. B: CD34 stained vessels. C: CD68 positive macrophages. D: HIF1α. E: VEGFR2. F: VEGF. G: NOTCH1. H: Dll4. Black bars represent 1000 μm (A) and 200 μm (B-H).</p

Boxplot of vascularization, measured as CQP values in upstream and downstream parts of early stage plaques.

<p>Boxplot of vascularization, measured as CQP values in upstream and downstream parts of early stage plaques.</p